GP9 ELISA Kit for Human(Homo sapiens) | EIAab.comGP9 ELISA Kit for Human(Homo sapiens)

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GP9 (Gene name),

Platelet glycoprotein IX (Protein name ), GPIX_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

GP9;

Protein name:

Platelet glycoprotein IX(GP-IX;GPIX);

Alternative:

Glycoprotein 9;

CD:

CD42a;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

GP-Ib alpha and beta are disulfide linked. GP-IX is complexed with the GP-Ib heterodimer via a non covalent linkage.

Function:

The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib.

Subcellular Location:

Membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

177

Sequence:

50:

100:

150:

177:

DVALVAVAAL | GLALLAGLLC | ATTEALD

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.1144

String:

P14770

KEGG:

hsa:2815

STRING:

9606.ENSP00000303942

SMR:

P14770

MIM:

173515

Pfam:

PF01462

Uniprot:

P14770

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ELISA Kit for Human GP-IX

Cat.:

E1904h

Price:

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Manual:

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MSDS:

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Packing:

96T

Range:

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ELISA Kit for Human GP-IX

Cat.:

E1904m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human GP-IX

Cat.:

U1904m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human GP-IX

Cat.:

U1904h

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human GP-IX

Cat.:

P1904Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human GP-IX

Cat.:

P1904Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human GP-IX

Protein for Human GP-IX

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Human platelet glycoprotein IX. Characterization of cDNA and localization of the gene to chromosome 3."
Hickey M.J. , Deaven L.L. , Roth G.J.
FEBS Lett.274:189-192(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 17-33 AND 98-109
2.

Roth G.J.
Submitted (1997-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION TO 125
3.

"Characterization of the gene encoding human platelet glycoprotein IX."
Hickey M.J. , Roth G.J.
J. Biol. Chem.268:3438-3443(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
tissue: Liver.
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT THR-156
tissue: Pancreas.
5.

"Human platelet glycoprotein IX: an adhesive prototype of leucine-rich glycoproteins with flank-center-flank structures."
Hickey M.J. , Williams S.A. , Roth G.J.
Proc. Natl. Acad. Sci. U.S.A.86:6773-6777(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 12-177;PROTEIN SEQUENCE OF 17-33 AND 98-109
6.

"Corrected DNA sequence of the platelet glycoprotein IX gene."
Hayashi T. , Suzuki K.
Thromb. Haemost.77:1034-1035(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 58-141
7.

"Isolation and characterization of human platelet glycoprotein IX."
Roth G.J. , Ozols J. , Nugent D.J. , Williams S.A.
Biochem. Biophys. Res. Commun.156:931-939(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 17-33
8.

"Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides."
Gevaert K. , Goethals M. , Martens L. , Van Damme J. , Staes A. , Thomas G.R. , Vandekerckhove J.
Nat. Biotechnol.21:566-569(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 17-27
tissue: Platelet.
9.

"Double heterozygosity for mutations in the platelet glycoprotein IX gene in three siblings with Bernard-Soulier syndrome."
Wright S.D. , Michaelides K. , Johnson D.J. , West N.C. , Tuddenham E.G.
Blood81:2339-2347(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS BSS GLY-37 AND SER-61
10.

"A phenylalanine-55 to serine amino-acid substitution in the human glycoprotein IX leucine-rich repeat is associated with Bernard-Soulier syndrome."
Noris P. , Simsek S. , Stibbe J. , von dem Borne A.E.G.K.
Br. J. Haematol.97:312-320(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT BSS SER-71
11.

"A new variant of Bernard-Soulier syndrome characterized by dysfunctional glycoprotein (GP) Ib and severely reduced amounts of GPIX and GPV."
Noris P. , Arbustini E. , Spedini P. , Belletti S. , Balduini C.L.
Br. J. Haematol.103:1004-1013(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT BSS PRO-56
12.

"Cys97-->Tyr mutation in the glycoprotein IX gene associated with Bernard-Soulier syndrome."
Kunishima S. , Tomiyama Y. , Honda S. , Kurata Y. , Kamiya T. , Ozawa K. , Saito H.
Br. J. Haematol.107:539-545(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT BSS TYR-113
13.

"Identification of a new mutation in platelet glycoprotein IX (GPIX) in a patient with Bernard-Soulier syndrome."
Rivera C.E. , Villagra J. , Riordan M. , Williams S. , Lindstrom K.J. , Rick M.E.
Br. J. Haematol.112:105-108(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT BSS ARG-24
14.

"A novel point mutation in the transmembrane domain of platelet glycoprotein IX gene identified in a Bernard-Soulier syndrome patient."
Wang Z. , Shi J. , Han Y.
Zhonghua Xue Ye Xue Za Zhi22:464-466(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT BSS THR-156
15.

"A Leu7-to-Pro mutation in the signal peptide of platelet glycoprotein (GP)IX in a case of Bernard-Soulier syndrome abolishes surface expression of the GPIb-V-IX complex."
Lanza F. , de la Salle C. , Baas M.-J. , Schwartz A. , Boval B. , Cazenave J.-P. , Caen J.P.
Br. J. Haematol.118:260-266(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT BSS PRO-7

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