HBG1 ELISA Kit for Human(Homo sapiens) | EIAab.comHBG1 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > HBG1(Gene name) > Human

HBG1 (Gene name),

Hemoglobin subunit gamma-1 (Protein name ), HBG1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

HBG1(PRO2979);

Protein name:

Hemoglobin subunit gamma-1;

Alternative:

Hb F Agamma;Gamma-1-globin;Hemoglobin gamma-A chain;Hemoglobin gamma-1 chain;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Heterotetramer of two alpha chains and two gamma chains in fetal hemoglobin (Hb F). In the case of deletions affecting one or more of the alpha chains the excess gamma chains form homotetramers that exhibit neither Bohr effect nor heme-heme cooperativity (hemoglobin Bart's).

Function:

Gamma chains make up the fetal hemoglobin F, in combination with alpha chains.

Subcellular Location:

N/A

Protein Attributes:

Sequence length:

147

Sequence:

50:

100:

147:

PENFKLLGNV | LVTVLAIHFG | KEFTPEVQAS | WQKMVTAVAS | ALSSRYH

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P69891

UniGene:

Hs.712539

MIM:

142200

KEGG:

hsa:3047

SMR:

P69891

Pfam:

PF00042

UniGene:

Hs.702189

STRING:

9606.ENSP00000327431

Uniprot:

P69891

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ELISA Kit for Human Hemoglobin subunit gamma-1

Cat.:

E0996h

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96T

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CLIA Kit for Human Hemoglobin subunit gamma-1

Cat.:

U0996h

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96T

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Polyclonal Antibody for Human Hemoglobin subunit gamma-1

Cat.:

P0996Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Hemoglobin subunit gamma-1

Protein for Human Hemoglobin subunit gamma-1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Human fetal G gamma- and A gamma-globin genes: complete nucleotide sequences suggest that DNA can be exchanged between these duplicated genes."
Slightom J.L. , Blechl A.E. , Smithies O.
Cell21:627-638(1980) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
2.

"A history of the human fetal globin gene duplication."
Shen S. , Slightom J.L. , Smithies O.
Cell26:191-203(1981) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.

"Functional prediction of the coding sequences of 75 new genes deduced by analysis of cDNA clones from human fetal liver."
Zhang C. , Yu Y. , Zhang S. , Wei H. , Bi J. , Zhou G. , Dong C. , Zai Y. , Xu W. , Gao F. , Liu M. , He F.
Submitted (1999-02) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Fetal liver.
4.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT THR-76
tissue: Lung.
tissue: Placenta.
6.

"Homo sapiens HBG1 gene with a 4 bp deletion upstream of the promoter region."
Seelig H.-P. , Vogel M. , Wiemann C. , Renz M.
Submitted (2002-02) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-30
7.

Lubec G. , Afjehi-Sadat L. , Chen W.-Q. , Sun Y.
Submitted (2008-12) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-60; 67-77 AND 84-145;IDENTIFICATION BY MASS SPECTROMETRY
tissue: Brain.
tissue: Cajal-Retzius cell.
tissue: Fetal brain cortex.
8.

"The M gamma chain of human fetal hemoglobin is an A gamma chain with an in vitro modification of gamma 141 leucine to hydroxyleucine."
Wilson J.B. , Brennan S.O. , Allen J. , Shaw J.G. , Gu L.H. , Huisman T.H.
J. Chromatogr. A617:37-42(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MODIFICATION AT LEU-142
9.

"Haemoglobin level, proportion of haemoglobin Bart's and haemoglobin Portland in fetuses affected by homozygous alpha0-thalassemia from 12 to 40 weeks' gestation."
Li T.K. , Leung K.Y. , Lam Y.H. , Tang M.H. , Chan V.
Prenat. Diagn.30:1126-1130(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT;DEVELOPMENTAL STAGE
10.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
11.

"Hemoglobin F level in different hemoglobin variants."
Olufemi A.E. , Sola O.B. , Oluwaseyi B.E. , Ajani R.A. , Olusoji M.O. , Olubunmi H.R.
Korean J. Hematol.46:118-122(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT;DEVELOPMENTAL STAGE
12.

"Fetal hemoglobin levels and morbidity in untransfused patients with beta-thalassemia intermedia."
Musallam K.M. , Sankaran V.G. , Cappellini M.D. , Duca L. , Nathan D.G. , Taher A.T.
Blood119:364-367(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT;DEVELOPMENTAL STAGE
13.

"Oligomerization and ligand binding in a homotetrameric hemoglobin: two high-resolution crystal structures of hemoglobin Bart's (gamma(4)), a marker for alpha-thalassemia."
Kidd R.D. , Baker H.M. , Mathews A.J. , Brittain T. , Baker E.N.
Protein Sci.10:1739-1749(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.7 ANGSTROMS) OF HOMOTETRAMER;SUBUNIT
14.

"Human fetal hemoglobin F 1. Acetylation status."
Stegink L.D. , Meyer P.D. , Brummel M.C.
J. Biol. Chem.246:3001-3007(1971) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION AT GLY-2
15.

"Hb F-Baskent or alpha 2A gamma 128(H6)Ala-->Thr."
Altay C. , Gurgey A. , Wilson J.B. , Hu H. , Webber B.B. , Kutlar F. , Huisman T.H.J.
Hemoglobin12:87-89(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT BASKENT THR-129
16.

"Hb F-Beech Island or alpha 2A gamma 2(53)(D4)Ala-->Asp."
Chen S.S. , Wilson J.B. , Webber B.B. , Huisman T.H.J.
Hemoglobin9:525-529(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT BEECH ISLAND ASP-54
17.

"Hb F-Bonaire-Ga or alpha 2 A gamma 2 39(C5) Gln replaced by Arg, characterized by high pressure liquid chromatographic and microsequencing procedures."
Nakatsuji T. , Headlee M. , Lam H. , Wilson J.B. , Huisman T.H.J.
Hemoglobin6:599-606(1982) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT BONAIRE ARG-40
18.

"Hb F-Calluna or alpha 2 gamma 2(12 Thr replaced by Arg; 75Ile; 136Ala) in a Caucasian baby."
Nakatsuji T. , Lam H. , Huisman T.H.J.
Hemoglobin7:563-566(1983) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CALLUNA ARG-13
19.

"Hb F-Cobb or alpha(2)A gamma(2)37(C3)Trp-->Gly."
Chen S.S. , Webber B.B. , Kutlar A. , Wilson J.B. , Huisman T.H.J.
Hemoglobin9:617-619(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT COBB GLY-38
20.

"Hb F-Dammam or alpha 2A gamma 2(79) (EF3) Asp-->Asn."
Al-Awamy B.H. , Niazi G.A. , Al-Mouzan M.I. , Wilson J.B. , Chen S.S. , Webber B.B. , Huisman T.H.J.
Hemoglobin9:171-173(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT DAMMAM ASN-80
21.

"Genetic haemoglobin abnormalities in about 9000 Black and 7000 White newborns; haemoglobin F Dickinson (Agamma97His-Arg), a new variant."
Schneider R.G. , Haggard M.E. , Gustavson L.P. , Brimhall B. , Jones R.T.
Br. J. Haematol.28:515-524(1974) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT DICKINSON ARG-98
22.

"Hb F-Fukuyama or A gamma T43(CD2)Asp-->Asn."
Hidaka K. , Iuchi I. , Nakahara H. , Iwakawa G.
Hemoglobin13:93-96(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT FUKUYAMA ASN-44
23.

"Haemoglobin F Hull (gamma-121 glutamic acid-->lysine), homologous with haemoglobins O Arab and O Indonesia."
Sacker L.S. , Beale D. , Black A.J. , Huntsman R.G. , Lehmann H. , Lorkin P.A.
BMJ3:531-533(1967) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HULL LYS-122
24.

"Survey of cord blood hemoglobin in Japan and identification of two new gamma chain variants."
Fuyuno K. , Torigoe T. , Ohba Y. , Matsuoka M. , Miyaji T.
Hemoglobin5:139-151(1981) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT IWATA ARG-73
25.

"Characterization of a new fetal hemoglobin variant, Hb F Izumi A gamma 6Glu replaced by Gly, by molecular secondary ion mass spectrometry."
Wada Y. , Hayashi A. , Masanori F. , Katakuse I. , Ichihara T. , Nakabushi H. , Matsuo T. , Sakurai T. , Matsuda H.
Biochim. Biophys. Acta749:244-248(1983) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT IZUMI GLY-7
26.

"Haemoglobin F Jamaica (alpha-2 gamma-2 61 Lys leads to Glu; 136 Ala)."
Ahern E.J. , Jones R.T. , Brimhall B. , Gray R.H.
Br. J. Haematol.18:369-375(1970) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT JAMAICA GLU-62
27.

"Hb F-Jiangsu, the first gamma chain variant with a valine->methionine substitution: alpha 2A gamma 2 134(H12)Val->Met."
Plaseska D. , Kutlar F. , Wilson J.B. , Webber B.B. , Zeng Y.-T. , Huisman T.H.J.
Hemoglobin14:177-183(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT JIANGSU MET-135
28.

"A new gamma chain variant, HB F Kotobuki or AI gamma 6 (A3) Glu leads to Gly."
Yoshinaka H. , Ohba Y. , Hattori Y. , Matsuoka M. , Miyaji T. , Fuyuno K.
Hemoglobin6:37-42(1982) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT KOTOBUKI GLY-7
29.

"Structural identification of haemoglobin F Kuala Lumpur: alpha2 gamma2 22(B4)Asp leads to Gly; 136 Ala."
Lie-Injo L.E. , Wiltshire B.B. , Lehmann H.
Biochim. Biophys. Acta322:224-230(1973) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT KUALA LUMPUR GLY-23
30.

"Hb F-Macedonia-I or alpha 2A gamma (2)2(NA2)His-->Gln."
Plaseska D. , Cepreganova-Krstik B. , Momirovska A. , Efremov G.D.
Hemoglobin18:241-245(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT MACEDONIA-I GLN-3
31.

"Hb F-Pendergrass, an A gamma I variant with a Pro-->Arg substitution at position gamma 36(C2)."
Chen S.S. , Wilson J.B. , Huisman T.H.J.
Hemoglobin9:73-77(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT PENDERGRASS ARG-37
32.

"A new gamma chain variant: Hb F-Pordenone [gamma 6(A3) Glu replaced by Gln: 75ILE: 136ALA]."
Nakatsuji T. , Webber B. , Lam H. , Wilson J.B. , Huisman T.H.J. , Sciarratta G.V. , Sansone G. , Molaro G.L.
Hemoglobin6:397-401(1982) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT PORDENONE GLN-7
33.

"A new Hb variant: Hb F Sardinia gamma75(E19) isoleucine leads to threonine found in a family with Hb G Philadelphia, beta-chain deficiency and a Lepore-like haemoglobin indistinguishable from Hb A2."
Grifone V. , Kamuzora H. , Lehmann H. , Charlesworth D.
Acta Haematol.53:347-355(1975) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT SARDINIA THR-76
34.

"Hb F-Siena (alpha 2 a gamma t2 121 (GH4) Glu leads to Lys). A new fetal hemoglobin variant."
Care A. , Marinucci M. , Massa A. , Maffi D. , Sposi N.M. , Improta T. , Tentori L.
Hemoglobin7:79-83(1983) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT SIENA LYS-122
35.

"Haemoglobin F Texas I(alpha-2,gamma-2-5glu-lys): a variant of haemoglobin F."
Jenkins G.C. , Beale D. , Black A.J. , Huntsman R.G. , Lehmann H.
Br. J. Haematol.13:252-255(1967) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT TEXAS-1 LYS-6
36.

"Haemoglobin F Victoria Jubilee (alpha 2 A gamma 2 80 Asp-Try)."
Ahern E. , Holder W. , Ahern V. , Serjeant G.R. , Serjeant B. , Forbes M. , Brimhall B. , Jones R.T.
Biochim. Biophys. Acta393:188-194(1975) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT VICTORIA JUBILEE TYR-81
37.

"Gamma chain abnormalities and gamma-globin gene rearrangements in newborn babies of various populations."
Huisman T.H.J. , Kutlar F. , Gu L.H.
Hemoglobin15:349-379(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT WOODSTOCK LYS-41
38.

"Hb F-Xin-Su or A gamma I73(E17)Asp-->His: a new slow-moving fetal hemoglobin variant."
Ma M. , Hu H. , Kutlar F. , Wilson J.B. , Huisman T.H.J.
Hemoglobin11:473-479(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT XIN-SU HIS-74
39.

"Hb F-Xinjiang or A gamma T25(B7)Gly-->Arg: a new slow-moving unstable fetal hemoglobin variant."
Hu H. , Ma M.
Hemoglobin11:465-472(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT XINJIANG ARG-26
40.

"HB F-Yamaguchi (gamma 75Thr, gamma 80Asn, gamma 136Ala) is associated with G gamma-thalassemia."
Nakatsuji T. , Ohba Y. , Huisman T.H.J.
Am. J. Hematol.16:189-192(1984) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT YAMAGUCHI ASN-81

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