SERPIND1 ELISA Kit for Human(Homo sapiens) | EIAab.comSERPIND1 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > SERPIND1(Gene name) > Human

SERPIND1 (Gene name),

Heparin cofactor 2 (Protein name ), HEP2_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

SERPIND1(HCF2);

Protein name:

Heparin cofactor 2;

Alternative:

Protease inhibitor leuserpin-2(HLS2);Heparin cofactor II(HC-II);Serpin D1;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Peptides at the N-terminal of HC-II have chemotactic activity for both monocytes and neutrophils.

Subcellular Location:

N/A

Protein Attributes:

Sequence length:

499

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

499:

QATTVTTVGF | MPLSTQVRFT | VDRPFLFLIY | EHRTSCLLFM | GRVANPSRS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P05546

STRING:

9606.ENSP00000215727

UniGene:

Hs.474270

KEGG:

hsa:3053

MIM:

142360

Pfam:

PF00079

SMR:

P05546

Uniprot:

P05546

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ELISA Kit for Human Heparin cofactor 2

Cat.:

E0284h

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Manual:

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Packing:

96T

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ELISA Kit for Human Heparin cofactor 2

Cat.:

E0284r

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MSDS:

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Packing:

96T

ELISA Kit for Human Heparin cofactor 2

Cat.:

E0284m

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MSDS:

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Packing:

96T

ELISA Kit for Human Heparin cofactor 2

MSDS:

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CLIA Kit for Human Heparin cofactor 2

Cat.:

U0284m

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MSDS:

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Packing:

96T

CLIA Kit for Human Heparin cofactor 2

Cat.:

U0284r

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Heparin cofactor 2

Cat.:

U0284h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Human Heparin cofactor 2

MSDS:

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Polyclonal Antibody for Human Heparin cofactor 2

Cat.:

P0284Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Heparin cofactor 2

Cat.:

P0284Rb-m

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40ug/0.2ml

Polyclonal Antibody for Human Heparin cofactor 2

Cat.:

P0284Rb-r

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Heparin cofactor 2

Protein for Human Heparin cofactor 2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Heparin cofactor II: cDNA sequence, chromosome localization, restriction fragment length polymorphism, and expression in Escherichia coli."
Blinder M.A. , Marasa J.C. , Reynolds C.H. , Deaven L.L. , Tollefsen D.M.
Biochemistry27:752-759(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"Complete nucleotide sequence of the gene for human heparin cofactor II and mapping to chromosomal band 22q11."
Herzog R. , Lutz S. , Blin N. , Marasa J.C. , Blinder M.A. , Tollefsen D.M.
Biochemistry30:1350-1357(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.

"A genome annotation-driven approach to cloning the human ORFeome."
Collins J.E. , Wright C.L. , Edwards C.A. , Davis M.P. , Grinham J.A. , Cole C.G. , Goward M.E. , Aguado B. , Mallya M. , Mokrab Y. , Huckle E.J. , Beare D.M. , Dunham I.
Genome Biol.5:R84.1-R84.11(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
4.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Liver.
5.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"A new member of the plasma protease inhibitor gene family."
Ragg H.
Nucleic Acids Res.14:1073-1088(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 19-499
7.

"Isolation and characterization of a partial cDNA clone for heparin cofactor II1."
Inhorn R.C. , Tollefsen D.M.
Biochem. Biophys. Res. Commun.137:431-436(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 333-499
8.

"Structural evidence for leucine at the reactive site of heparin cofactor II."
Griffith M.J. , Noyes C.M. , Tyndall J.A. , Church F.C.
Biochemistry24:6777-6782(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 20-52 AND 464-499
9.

"Structure and expression of the gene coding for the human serpin hLS2."
Ragg H. , Preibisch G.
J. Biol. Chem.263:12129-12134(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-119
10.

"Leukocyte chemoattractant peptides from the serpin heparin cofactor II."
Church F.C. , Pratt C.W. , Hoffman M.
J. Biol. Chem.266:704-709(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 58-85
11.

"The N-terminal acidic domain of heparin cofactor II mediates the inhibition of alpha-thrombin in the presence of glycosaminoglycans."
van Deerlin V.M.D. , Tollefsen D.M.
J. Biol. Chem.266:20223-20231(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION OF N-TERMINAL ACIDIC DOMAIN
12.

"Site-directed mutagenesis of arginine 103 and lysine 185 in the proposed glycosaminoglycan-binding site of heparin cofactor II."
Blinder M.A. , Tollefsen D.M.
J. Biol. Chem.265:286-291(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS OF ARG-122 AND LYS-204
13.

"Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
Liu T. , Qian W.-J. , Gritsenko M.A. , Camp D.G. II , Monroe M.E. , Moore R.J. , Smith R.D.
J. Proteome Res.4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-49 AND ASN-188
tissue: Plasma.
14.

"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-49 AND ASN-188
tissue: Liver.
15.

"A strategy for precise and large scale identification of core fucosylated glycoproteins."
Jia W. , Lu Z. , Fu Y. , Wang H.P. , Wang L.H. , Chi H. , Yuan Z.F. , Zheng Z.B. , Song L.N. , Han H.H. , Liang Y.M. , Wang J.L. , Cai Y. , Zhang Y.K. , Deng Y.L. , Ying W.T. , He S.M. , Qian X.H.
Mol. Cell. Proteomics8:913-923(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT ASN-49
16.

"Crystal structures of native and thrombin-complexed heparin cofactor II reveal a multistep allosteric mechanism."
Baglin T.P. , Carrell R.W. , Church F.C. , Esmon C.T. , Huntington J.A.
Proc. Natl. Acad. Sci. U.S.A.99:11079-11084(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS) OF 20-499;GLYCOSYLATION AT ASN-188 AND ASN-387;SULFATION AT TYR-79 AND TYR-92
17.

"Heparin cofactor IIOslo. Mutation of Arg-189 to His decreases the affinity for dermatan sulfate."
Blinder M.A. , Andersson T.R. , Abildgaard U. , Tollefsen D.M.
J. Biol. Chem.264:5128-5133(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT THPH10 HIS-208
18.

"Characterization of single-nucleotide polymorphisms in coding regions of human genes."
Cargill M. , Altshuler D. , Ireland J. , Sklar P. , Ardlie K. , Patil N. , Shaw N. , Lane C.R. , Lim E.P. , Kalyanaraman N. , Nemesh J. , Ziaugra L. , Friedland L. , Rolfe A. , Warrington J. , Lipshutz R. , Daley G.Q. , Lander E.S.
Nat. Genet.22:231-238(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT THPH10 HIS-208;VARIANTS THR-7 AND MET-442
19.

Cargill M. , Altshuler D. , Ireland J. , Sklar P. , Ardlie K. , Patil N. , Shaw N. , Lane C.R. , Lim E.P. , Kalyanaraman N. , Nemesh J. , Ziaugra L. , Friedland L. , Rolfe A. , Warrington J. , Lipshutz R. , Daley G.Q. , Lander E.S.
Nat. Genet.23:373-373(1999)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
20.

"Molecular mechanism of type I congenital heparin cofactor (HC) II deficiency caused by a missense mutation at reactive P2 site: HC II Tokushima."
Kanagawa Y. , Shigekiyo T. , Aihara K. , Akaike M. , Azuma H. , Matsumoto T.
Thromb. Haemost.85:101-107(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT THPH10 LEU-462;CHARACTERIZATION OF VARIANT THPH10 LEU-462
21.

"Homozygous deficiency of heparin cofactor II: relevance of P17 glutamate residue in serpins, relationship with conformational diseases, and role in thrombosis."
Corral J. , Aznar J. , Gonzalez-Conejero R. , Villa P. , Minano A. , Vaya A. , Carrell R.W. , Huntington J.A. , Vicente V.
Circulation110:1303-1307(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT THPH10 LYS-447

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