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Index > Protein center > HEPH(Gene name) > Human
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  • HEPH (Gene name),
  • Hephaestin (Protein name ),  HEPH_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    HEPH(UNQ2562/PRO6242;KIAA0698);
    Protein name:
    Hephaestin;
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    May function as a ferroxidase for ferrous (II) to ferric ion (III) conversion and may be involved in copper transport and homeostasis. Implicated in iron homeostasis and may mediate iron efflux associated to ferroportin 1.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    1158
    Sequence:
    50:
    MESGHLLWAL | LFMQSLWPQL | TDGATRVYYL | GIRDVQWNYA | PKGRNVITNQ | 
    100:
    PLDSDIVASS | FLKSDKNRIG | GTYKKTIYKE | YKDDSYTDEV | AQPAWLGFLG | 
    150:
    PVLQAEVGDV | ILIHLKNFAT | RPYTIHPHGV | FYEKDSEGSL | YPDGSSGPLK | 
    200:
    ADDSVPPGGS | HIYNWTIPEG | HAPTDADPAC | LTWIYHSHVD | APRDIATGLI | 
    250:
    GPLITCKRGA | LDGNSPPQRQ | DVDHDFFLLF | SVVDENLSWH | LNENIATYCS | 
    300:
    DPASVDKEDE | TFQESNRMHA | INGFVFGNLP | ELNMCAQKRV | AWHLFGMGNE | 
    350:
    IDVHTAFFHG | QMLTTRGHHT | DVANIFPATF | VTAEMVPWEP | GTWLISCQVN | 
    400:
    SHFRDGMQAL | YKVKSCSMAP | PVDLLTGKVR | QYFIEAHEIQ | WDYGPMGHDG | 
    450:
    STGKNLREPG | SISDKFFQKS | SSRIGGTYWK | VRYEAFQDET | FQEKMHLEED | 
    500:
    RHLGILGPVI | RAEVGDTIQV | VFYNRASQPF | SMQPHGVFYE | KDYEGTVYND | 
    550:
    GSSYPGLVAK | PFEKVTYRWT | VPPHAGPTAQ | DPACLTWMYF | SAADPIRDTN | 
    600:
    SGLVGPLLVC | RAGALGADGK | QKGVDKEFFL | LFTVLDENKS | WYSNANQAAA | 
    650:
    MLDFRLLSED | IEGFQDSNRM | HAINGFLFSN | LPRLDMCKGD | TVAWHLLGLG | 
    700:
    TETDVHGVMF | QGNTVQLQGM | RKGAAMLFPH | TFVMAIMQPD | NLGTFEIYCQ | 
    750:
    AGSHREAGMR | AIYNVSQCPG | HQATPRQRYQ | AARIYYIMAE | EVEWDYCPDR | 
    800:
    SWEREWHNQS | EKDSYGYIFL | SNKDGLLGSR | YKKAVFREYT | DGTFRIPRPR | 
    850:
    TGPEEHLGIL | GPLIKGEVGD | ILTVVFKNNA | SRPYSVHAHG | VLESTTVWPL | 
    900:
    AAEPGEVVTY | QWNIPERSGP | GPNDSACVSW | IYYSAVDPIK | DMYSGLVGPL | 
    950:
    AICQKGILEP | HGGRSDMDRE | FALLFLIFDE | NKSWYLEENV | ATHGSQDPGS | 
    1000:
    INLQDETFLE | SNKMHAINGK | LYANLRGLTM | YQGERVAWYM | LAMGQDVDLH | 
    1050:
    TIHFHAESFL | YRNGENYRAD | VVDLFPGTFE | VVEMVASNPG | TWLMHCHVTD | 
    1100:
    HVHAGMETLF | TVFSRTEHLS | PLTVITKETE | KAVPPRDIEE | GNVKMLGMQI | 
    1150:
    PIKNVEMLAS | VLVAISVTLL | LVVLALGGVV | WYQHRQRKLR | RNRRSILDDS | 
    1158:
    FKLLSFKQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    UniGene:
    MIM:
    SMR:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Hephaestin
    Cat.:
    E0338h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Hephaestin
    Cat.:
    E0338r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Hephaestin
    Cat.:
    E0338m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Hephaestin
    Cat.:
    U0338r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Hephaestin
    Cat.:
    U0338h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Hephaestin
    Cat.:
    U0338m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Hephaestin
    Cat.:
    P0338Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Hephaestin
    Cat.:
    P0338Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Hephaestin
    Cat.:
    P0338Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Hephaestin
    Monoclonal Antibody for Human Hephaestin
    Monoclonal Antibody for Human Hephaestin
    Protein for Human Hephaestin
    Protein for Human Hephaestin
    Protein for Human Hephaestin

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Analysis of the human hephaestin gene and protein: comparative modelling of the N-terminus ecto-domain based upon ceruloplasmin."
      Syed B.A. , Beaumont N.J. , Patel A. , Naylor C.E. , Bayele H.K. , Joannou C.L. , Rowe P.S.N. , Evans R.W. , Srai S.K.S.
      Protein Eng.15:205-214(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    2. 2.
      Zhao K.W.
      Submitted (1999-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    3. 3.
      "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
      Clark H.F. , Gurney A.L. , Abaya E. , Baker K. , Baldwin D.T. , Brush J. , Chen J. , Chow B. , Chui C. , Crowley C. , Currell B. , Deuel B. , Dowd P. , Eaton D. , Foster J.S. , Grimaldi C. , Gu Q. , Hass P.E. , more...
      Genome Res.13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
    4. 4.
      "The DNA sequence of the human X chromosome."
      Ross M.T. , Grafham D.V. , Coffey A.J. , Scherer S. , McLay K. , Muzny D. , Platzer M. , Howell G.R. , Burrows C. , Bird C.P. , Frankish A. , Lovell F.L. , Howe K.L. , Ashurst J.L. , Fulton R.S. , Sudbrak R. , Wen G. , Jones M.C. , more...
      Nature434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Colon.
    7. 7.
      "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."
      Ishikawa K. , Nagase T. , Suyama M. , Miyajima N. , Tanaka A. , Kotani H. , Nomura N. , Ohara O.
      DNA Res.5:169-176(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 55-1158 (ISOFORM 1)
      tissue: Brain.
    8. 8.
      "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."
      Nakajima D. , Okazaki N. , Yamakawa H. , Kikuno R. , Ohara O. , Nagase T.
      DNA Res.9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
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