HPN ELISA Kit for Human(Homo sapiens) | EIAab.comHPN ELISA Kit for Human(Homo sapiens)

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Index > Protein center > HPN(Gene name) > Human

HPN (Gene name),

Serine protease hepsin (Protein name ), HEPS_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Citations (1)

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Gene name:

HPN(TMPRSS1);

Protein name:

Serine protease hepsin;

Alternative:

Transmembrane protease serine 1;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Plays an essential role in cell growth and maintenance of cell morphology.

Subcellular Location:

Membrane Single-pass type II membrane protein

Protein Attributes:

Sequence length:

417

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

417:

FQAIKTHSEA | SGMVTQL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P05981

STRING:

9606.ENSP00000262626

MIM:

142440

Pfam:

PF09272

KEGG:

hsa:3249

String:

P05981

UniGene:

Hs.182385

Uniprot:

P05981

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ELISA Kit for Human Serine protease hepsin

Cat.:

E1856h

Price:

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Manual:

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MSDS:

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Packing:

96T

Range:

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ELISA Kit for Human Serine protease hepsin

Cat.:

E1856m

Price:

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MSDS:

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Packing:

96T

ELISA Kit for Human Serine protease hepsin

Cat.:

E1856r

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MSDS:

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Packing:

96T

CLIA Kit for Human Serine protease hepsin

Cat.:

U1856h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Serine protease hepsin

Cat.:

U1856m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Serine protease hepsin

Cat.:

U1856r

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Serine protease hepsin

Cat.:

P1856Rb-r

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Serine protease hepsin

Cat.:

P1856Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Serine protease hepsin

Cat.:

P1856Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Serine protease hepsin

Protein for Human Serine protease hepsin

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Citations

[1].

"Alpha-methylacyl-CoA racemase and hepsin as urinary prostate cancer markers"

W D Sroka, M Adamowski, P Słupski, et al.

From:Int J Biol Markers

References

1.

"A novel trypsin-like serine protease (hepsin) with a putative transmembrane domain expressed by human liver and hepatoma cells."
Leytus S.P. , Loeb K.R. , Hagen F.S. , Kurachi K. , Davie E.W.
Biochemistry27:1067-1074(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Liver.
2.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Mammary gland.
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Pancreas.
tissue: Spleen.
4.

"Hepsin, a cell membrane-associated protease. Characterization, tissue distribution, and gene localization."
Tsuji A. , Torres-Rosado A. , Arai T. , le Beau M.M. , Lemons R.S. , Chou S.H. , Kurachi K.
J. Biol. Chem.266:16948-16953(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION
5.

"Hepsin, a putative cell-surface serine protease, is required for mammalian cell growth."
Torres-Rosado A. , O'Shea K.S. , Tsuji A. , Chou S.-H. , Kurachi K.
Proc. Natl. Acad. Sci. U.S.A.90:7181-7185(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION
6.

"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-112
tissue: Liver.
7.

"Proteolytic activation of pro-macrophage-stimulating protein by hepsin."
Ganesan R. , Kolumam G.A. , Lin S.J. , Xie M.H. , Santell L. , Wu T.D. , Lazarus R.A. , Chaudhuri A. , Kirchhofer D.
Mol. Cancer Res.9:1175-1186(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
8.

"TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike protein."
Heurich A. , Hofmann-Winkler H. , Gierer S. , Liepold T. , Jahn O. , Poehlmann S.
J. Virol.88:1293-1307(2014) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
9.

"Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancers."
Herter S. , Piper D.E. , Aaron W. , Gabriele T. , Cutler G. , Cao P. , Bhatt A.S. , Choe Y. , Craik C.S. , Walker N. , Meininger D. , Hoey T. , Austin R.J.
Biochem. J.390:125-136(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.55 ANGSTROMS) OF 46-417;DISULFIDE BONDS;FUNCTION

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