HLA-G ELISA Kit for Human(Homo sapiens) | EIAab.comHLA-G ELISA Kit for Human(Homo sapiens)

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HLA-G (Gene name),

HLA class I histocompatibility antigen, alpha chain G (Protein name ), HLAG_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

HLA-G(HLA-6.0;HLAG);

Protein name:

HLA class I histocompatibility antigen, alpha chain G;

Alternative:

MHC class I antigen G;HLA G antigen;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Heterodimer of an alpha chain and a beta chain (beta-2-microglobulin). Homodimer; disulfide-linked. Binds to LILRB1 and LILRB2.

Function:

Involved in the presentation of foreign antigens to the immune system. Plays a role in maternal tolerance of the fetus by mediating protection from the deleterious effects of natural killer cells, cytotoxic T lymphocytes, macrophages and mononuclear cells.

Subcellular Location:

Membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

338

Sequence:

50:

100:

150:

200:

250:

300:

338:

SSLPTIPIMG | IVAGLVVLAA | VVTGAAVAAV | LWRKKSSD

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.512152

Pfam:

PF07654

SMR:

P17693

MIM:

142871

KEGG:

hsa:3135

STRING:

9606.ENSP00000387624

String:

P17693

Uniprot:

P17693

FOR

ELISA Kit for Human HLA class I histocompatibility antigen, alpha chain G

Cat.:

E1386h

Price:

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Manual:

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MSDS:

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Packing:

96T

Range:

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CLIA Kit for Human HLA class I histocompatibility antigen, alpha chain G

Cat.:

U1386h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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Polyclonal Antibody for Human HLA class I histocompatibility antigen, alpha chain G

Cat.:

P1386Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human HLA class I histocompatibility antigen, alpha chain G

Protein for Human HLA class I histocompatibility antigen, alpha chain G

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The mRNA of a human class I gene HLA G/HLA 6.0 exhibits a restricted pattern of expression."
Shukla H. , Swaroop A. , Srivastava R. , Weissman S.M.
Nucleic Acids Res.18:2189-2189(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Fetal eye.
2.

"A human major histocompatibility complex class I gene that encodes a protein with a shortened cytoplasmic segment."
Geraghty D.E. , Koller B.H. , Orr H.T.
Proc. Natl. Acad. Sci. U.S.A.84:9145-9149(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.

Ishitani A. , Geraghty D.E.
Submitted (1992-04) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Placenta.
4.

"A 356-Kb sequence of the subtelomeric part of the MHC class I region."
Hampe A. , Coriton O. , Andrieux N. , Carn G. , Lepourcelet M. , Mottier S. , Dreano S. , Gatius M.T. , Hitte C. , Soriano N. , Galibert F.
DNA Seq.10:263-299(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
5.

"Homo sapiens 2,229,817bp genomic DNA of 6p21.3 HLA class I region."
Shiina S. , Tamiya G. , Oka A. , Inoko H.
Submitted (1999-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"Disulfide bond-mediated dimerization of HLA-G on the cell surface."
Boyson J.E. , Erskine R. , Whitman M.C. , Chiu M. , Lau J.M. , Koopman L.A. , Valter M.M. , Angelisova P. , Horejsi V. , Strominger J.L.
Proc. Natl. Acad. Sci. U.S.A.99:16180-16185(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT;MUTAGENESIS OF CYS-66;DISULFIDE BOND AT CYS-66
7.

"Crystal structure of HLA-G: a nonclassical MHC class I molecule expressed at the fetal-maternal interface."
Clements C.S. , Kjer-Nielsen L. , Kostenko L. , Hoare H.L. , Dunstone M.A. , Moses E. , Freed K. , Brooks A.G. , Rossjohn J. , McCluskey J.
Proc. Natl. Acad. Sci. U.S.A.102:3360-3365(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF 26-300
8.

"Efficient leukocyte Ig-like receptor signaling and crystal structure of disulfide-linked HLA-G dimer."
Shiroishi M. , Kuroki K. , Ose T. , Rasubala L. , Shiratori I. , Arase H. , Tsumoto K. , Kumagai I. , Kohda D. , Maenaka K.
J. Biol. Chem.281:10439-10447(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.2 ANGSTROMS) OF 25-300;DISULFIDE BONDS

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