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Index > Protein center > Hmgb1(Gene name) > Rat
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  • Hmgb1 (Gene name),
  • High mobility group protein B1 (Protein name ),  HMGB1_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    Hmgb1(Hmg-1;Hmg1);
    Protein name:
    High mobility group protein B1;
    Alternative:
    Heparin-binding protein p30;Amphoterin;High mobility group protein 1(HMG-1);
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Component of the RAG complex composed of core components RAG1 and RAG2, and associated component HMGB1 or HMGB2.
    Function:
    DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells.
    Subcellular Location:
    Nucleus Cytoplasm Chromosome Associated with the plasma membrane of filipodia in process-growing cells, and also deposited into the substrate-attached material.
    Protein Attributes:
    Sequence length:
    215
    Sequence:
    50:
    MGKGDPKKPR | GKMSSYAFFV | QTCREEHKKK | HPDASVNFSE | FSKKCSERWK | 
    100:
    TMSAKEKGKF | EDMAKADKAR | YEREMKTYIP | PKGETKKKFK | DPNAPKRPPS | 
    150:
    AFFLFCSEYR | PKIKGEHPGL | SIGDVAKKLG | EMWNNTAADD | KQPYEKKAAK | 
    200:
    LKEKYEKDIA | AYRAKGKPDA | AKKGVVKAEK | SKKKKEEEDD | EEDEEDEEEE | 
    215:
    EEEEDEDEEE | DDDDE
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    String:
    KEGG:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rat High mobility group protein B1
    Cat.:
    E0399m
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Rat High mobility group protein B1
    MSDS:
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    ELISA Kit for Rat High mobility group protein B1
    Cat.:
    E0399p
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    96T
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    ELISA Kit for Rat High mobility group protein B1
    Cat.:
    E0399r
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    MSDS:
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    96T
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    ELISA Kit for Rat High mobility group protein B1
    Cat.:
    E0399h
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    96T
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    ELISA Kit for Rat High mobility group protein B1
    Cat.:
    E0399d
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    Packing:
    96T
    ELISA Kit for Rat High mobility group protein B1
    Cat.:
    E0399b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat High mobility group protein B1
    Cat.:
    U0399c
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    Packing:
    96T
    CLIA Kit for Rat High mobility group protein B1
    Cat.:
    U0399b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat High mobility group protein B1
    Cat.:
    U0399d
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat High mobility group protein B1
    Cat.:
    U0399p
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat High mobility group protein B1
    Cat.:
    U0399r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat High mobility group protein B1
    Cat.:
    U0399h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat High mobility group protein B1
    Cat.:
    U0399m
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    Polyclonal Antibody for Rat High mobility group protein B1
    Polyclonal Antibody for Rat High mobility group protein B1
    Polyclonal Antibody for Rat High mobility group protein B1
    Polyclonal Antibody for Rat High mobility group protein B1
    Cat.:
    P0399Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat High mobility group protein B1
    Cat.:
    P0399Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat High mobility group protein B1
    Polyclonal Antibody for Rat High mobility group protein B1
    Cat.:
    P0399Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat High mobility group protein B1
    Monoclonal Antibody for Rat High mobility group protein B1
    Monoclonal Antibody for Rat High mobility group protein B1
    Monoclonal Antibody for Rat High mobility group protein B1
    Monoclonal Antibody for Rat High mobility group protein B1
    Monoclonal Antibody for Rat High mobility group protein B1
    Monoclonal Antibody for Rat High mobility group protein B1
    Protein for Rat High mobility group protein B1
    Cat.:
    R0399b
    Price:
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    Packing:
    1mg
    Purity:
    >90%
    Protein for Rat High mobility group protein B1
    Cat.:
    R0399d
    Price:
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    Packing:
    1mg
    Purity:
    >90%
    Protein for Rat High mobility group protein B1
    Cat.:
    R0399m
    Price:
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    Packing:
    1mg
    Purity:
    >90%
    Protein for Rat High mobility group protein B1
    Cat.:
    R0399p
    Price:
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    Packing:
    1mg
    Purity:
    >90%
    Protein for Rat High mobility group protein B1
    Cat.:
    R0399r
    Price:
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    Packing:
    1mg
    Purity:
    >90%
    Protein for Rat High mobility group protein B1
    Cat.:
    R0399h
    Price:
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    Packing:
    1mg
    Purity:
    >90%
    Protein for Rat High mobility group protein B1

    R&D Technical Data
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    12% SDS-PAGE analysis

              12% SDS-PAGE analysis

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    Precision
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    Linearity
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    References
    1. 1.
      "Nucleotide sequence of rat liver HMG1 cDNA."
      Paonessa G. , Frank R. , Cortese R.
      Nucleic Acids Res.15:9077-9077(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Sprague-Dawley.
      tissue: Liver.
    2. 2.
      Bianchi M.
      Submitted (1988-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
    3. 3.
      "30-kDa heparin-binding protein of brain (amphoterin) involved in neurite outgrowth. Amino acid sequence and localization in the filopodia of the advancing plasma membrane."
      Merenmies J. , Pihlaskari R. , Laitinen J. , Wartiovaara J. , Rauvala H.
      J. Biol. Chem.266:16722-16729(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE
    4. 4.
      "Amphoterin is associated with the development of the kidney."
      Ito T. , Suzuki A. , Horimoto N. , Imai E. , Hori M.
      Submitted (2000-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Sprague-Dawley.
      tissue: Kidney.
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Kidney.
      tissue: Prostate.
      tissue: Testis.
    6. 6.
      "The adhesive and neurite-promoting molecule p30: analysis of the amino-terminal sequence and production of antipeptide antibodies that detect p30 at the surface of neuroblastoma cells and of brain neurons."
      Rauvala H. , Merenmies J. , Pihlaskari R. , Korkolainen M. , Huhtala M.L. , Panula P.
      J. Cell Biol.107:2293-2305(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-21
    7. 7.
      "Structure of the HMG box motif in the B-domain of HMG1."
      Weir H.M. , Kraulis P.J. , Hill C.S. , Raine A.R.C. , Laue E.D. , Thomas J.O.
      EMBO J.12:1311-1319(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 88-165
    8. 8.
      "Structure of the A-domain of HMG1 and its interaction with DNA as studied by heteronuclear three- and four-dimensional NMR spectroscopy."
      Hardman C.H. , Broadhurst R.W. , Raine A.R.C. , Grasser K.D. , Thomas J.O. , Laue E.D.
      Biochemistry34:16596-16607(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 1-84
      strain: Sprague-Dawley.
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