Gene name:
HNRNPF (HNRPF) ;
Protein name:
Heterogeneous nuclear ribonucleoprotein F (hnRNP F) ;
Alternative:
Nucleolin-like protein mcs94-1 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Identified in the spliceosome C complex. Interacts with EIF2C1, EIF2C2, TBP and TXNL4/DIM1.
Function:
Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Plays a role in the regulation of alternative splicing events. Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state.
Subcellular Location:
Nucleus
nucleoplasm
Protein Attributes:
50:
MMLGPEGGEG | FVVKLRGLPW | SCSVEDVQNF | LSDCTIHDGA | AGVHFIYTRE |
100:
GRQSGEAFVE | LGSEDDVKMA | LKKDRESMGH | RYIEVFKSHR | TEMDWVLKHS |
150:
GPNSADSAND | GFVRLRGLPF | GCTKEEIVQF | FSGLEIVPNG | ITLPVDPEGK |
200:
ITGEAFVQFA | SQELAEKALG | KHKERIGHRY | IEVFKSSQEE | VRSYSDPPLK |
250:
FMSVQRPGPY | DRPGTARRYI | GIVKQAGLER | MRPGAYSTGY | GGYEEYSGLS |
300:
DGYGFTTDLF | GRDLSYCLSG | MYDHRYGDSE | FTVQSTTGHC | VHMRGLPYKA |
350:
TENDIYNFFS | PLNPVRVHIE | IGPDGRVTGE | ADVEFATHEE | AVAAMSKDRA |
400:
NMQHRYIELF | LNSTTGASNG | AYSSQVMQGM | GVSAAQATYS | GLESQSVSGC |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Human
Mouse
Rat
ELISA Kit for Human hnRNP F
ELISA Kit for Human hnRNP F
ELISA Kit for Human hnRNP F
ELISA Kit for Human hnRNP F
CLIA Kit for Human hnRNP F
CLIA Kit for Human hnRNP F
CLIA Kit for Human hnRNP F
CLIA Kit for Human hnRNP F
Polyclonal Antibody for Human hnRNP F
Polyclonal Antibody for Human hnRNP F
Polyclonal Antibody for Human hnRNP F
Polyclonal Antibody for Human hnRNP F
Monoclonal Antibody for Human hnRNP F
Monoclonal Antibody for Human hnRNP F
Monoclonal Antibody for Human hnRNP F
Monoclonal Antibody for Human hnRNP F
Protein for Human hnRNP F
Protein for Human hnRNP F
Protein for Human hnRNP F
Protein for Human hnRNP F
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 52-61; 78-83 AND 128-136
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
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more...
Nat. Genet.36:40-45(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
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Nature429:375-381(2004)
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[
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[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.
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more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT ARG-87
tissue :
Bone marrow .
tissue :
Lung .
tissue :
Ovary .
tissue :
Placenta .
tissue :
Uterus .
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 1-14; 53-68; 82-87; 99-114; 151-167; 180-185 AND 300-347;CLEAVAGE OF INITIATOR METHIONINE;ACETYLATION AT MET-1 AND MET-2;IDENTIFICATION BY MASS SPECTROMETRY
tissue :
B-cell lymphoma .
tissue :
Colon carcinoma .
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH TXNL4
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY;IDENTIFICATION IN THE SPLICEOSOMAL C COMPLEX
11.
"Sumoylation of heterogeneous nuclear ribonucleoproteins, zinc finger proteins, and nuclear pore complex proteins: a proteomic analysis."
Li T.
,
Evdokimov E.
,
Shen R.F.
,
Chao C.C.
,
Tekle E.
,
Wang T.
,
Stadtman E.R.
,
Yang D.C.
,
Chock P.B.
Proc. Natl. Acad. Sci. U.S.A.101:8551-8556(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUMOYLATION AT LYS-72
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
13.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH AGO1 AND AGO2
14.
"ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."
Matsuoka S.
,
Ballif B.A.
,
Smogorzewska A.
,
McDonald E.R. III
,
Hurov K.E.
,
Luo J.
,
Bakalarski C.E.
,
Zhao Z.
,
Solimini N.
,
Lerenthal Y.
,
Shiloh Y.
,
Gygi S.P.
,
Elledge S.J.
Science316:1160-1166(2007)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-161;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Embryonic kidney .
15.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
16.
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Cited for : ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1 AND MET-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
17.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-104;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
18.
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Cited for : ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-224;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
19.
"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V.
,
Vermeulen M.
,
Santamaria A.
,
Kumar C.
,
Miller M.L.
,
Jensen L.J.
,
Gnad F.
,
Cox J.
,
Jensen T.S.
,
Nigg E.A.
,
Brunak S.
,
Mann M.
Sci. Signal.3:RA3-RA3(2010)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
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Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-104 AND SER-187;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
20.
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Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
21.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-104;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
22.
"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Van Damme P.
,
Lasa M.
,
Polevoda B.
,
Gazquez C.
,
Elosegui-Artola A.
,
Kim D.S.
,
De Juan-Pardo E.
,
Demeyer K.
,
Hole K.
,
Larrea E.
,
Timmerman E.
,
Prieto J.
,
Arnesen T.
,
Sherman F.
,
Gevaert K.
,
Aldabe R.
Proc. Natl. Acad. Sci. U.S.A.109:12449-12454(2012)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1 AND MET-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
23.
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Cited for : STRUCTURE BY NMR OF 1-102; 103-194 AND 277-381 IN COMPLEX WITH BCL-X RNA;MUTAGENESIS OF PHE-120; PHE-156; HIS-178 AND TYR-180
24.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : STRUCTURE BY NMR OF 1-194 AND 277-381 IN COMPLEXES WITH AGGGAU RNA OLIGONUCLEOTIDE;FUNCTION;MUTAGENESIS OF TRP-20; GLU-84; ARG-116; PHE-120; LYS-150; LYS-173; ARG-179; TYR-180; GLU-182 AND PHE-184