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Index > Protein center > HSPA8(Gene name) > Human
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  • HSPA8 (Gene name),
  • Heat shock cognate 71 kDa protein (Protein name ),  HSP7C_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    HSPA8(HSC70;HSP73;HSPA10);
    Protein name:
    Heat shock cognate 71 kDa protein;
    Alternative:
    Heat shock 70 kDa protein 8;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with HSPH1/HSP105. Interacts with IRAK1BP1 (By similarity). Identified in a mRNP granule complex, at least composed of ACTB, ACTN4, DHX9, ERG, HNRNPA1, HNRNPA2B1, HNRNPAB, HNRNPD, HNRNPL, HNRNPR, HNRNPU, HSPA1, HSPA8, IGF2BP1, ILF2, ILF3, NCBP1, NCL, PABPC1, PABPC4, PABPN1, RPLP0, RPS3, RPS3A, RPS4X, RPS8, RPS9, SYNCRIP, TROVE2, YBX1 and untranslated mRNAs. Interacts with PACRG and TSC2. Interacts with BAG1. Interacts with SV40 VP1. Interacts with DNAJC7 (By similarity). Interacts with HERC5. Interacts with CITED1 (via N-terminus); the interaction suppresses the association of CITED1 to p300/CBP and Smad-mediated transcription transactivation.
    Function:
    Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Isoform 2 may function as an endogenous inhibitory regulator of HSC70 by competing the co-chaperones.
    Subcellular Location:
    Cytoplasm Melanosome Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Translocates rapidly from the cytoplasm to the nuclei, and especially to the nucleoli, upon heat shock. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
    Protein Attributes:
    Sequence length:
    646
    Sequence:
    50:
    MSKGPAVGID | LGTTYSCVGV | FQHGKVEIIA | NDQGNRTTPS | YVAFTDTERL | 
    100:
    IGDAAKNQVA | MNPTNTVFDA | KRLIGRRFDD | AVVQSDMKHW | PFMVVNDAGR | 
    150:
    PKVQVEYKGE | TKSFYPEEVS | SMVLTKMKEI | AEAYLGKTVT | NAVVTVPAYF | 
    200:
    NDSQRQATKD | AGTIAGLNVL | RIINEPTAAA | IAYGLDKKVG | AERNVLIFDL | 
    250:
    GGGTFDVSIL | TIEDGIFEVK | STAGDTHLGG | EDFDNRMVNH | FIAEFKRKHK | 
    300:
    KDISENKRAV | RRLRTACERA | KRTLSSSTQA | SIEIDSLYEG | IDFYTSITRA | 
    350:
    RFEELNADLF | RGTLDPVEKA | LRDAKLDKSQ | IHDIVLVGGS | TRIPKIQKLL | 
    400:
    QDFFNGKELN | KSINPDEAVA | YGAAVQAAIL | SGDKSENVQD | LLLLDVTPLS | 
    450:
    LGIETAGGVM | TVLIKRNTTI | PTKQTQTFTT | YSDNQPGVLI | QVYEGERAMT | 
    500:
    KDNNLLGKFE | LTGIPPAPRG | VPQIEVTFDI | DANGILNVSA | VDKSTGKENK | 
    550:
    ITITNDKGRL | SKEDIERMVQ | EAEKYKAEDE | KQRDKVSSKN | SLESYAFNMK | 
    600:
    ATVEDEKLQG | KINDEDKQKI | LDKCNEIINW | LDKNQTAEKE | EFEHQQKELE | 
    646:
    KVCNPIITKL | YQSAGGMPGG | MPGGFPGGGA | PPSGGASSGP | TIEEVD
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    MIM:
    String:
    SMR:
    UniGene:
    Pfam:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Heat shock cognate 71 kDa protein
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    ELISA Kit for Human Heat shock cognate 71 kDa protein
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    ELISA Kit for Human Heat shock cognate 71 kDa protein
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    E1094h
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    ELISA Kit for Human Heat shock cognate 71 kDa protein
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    E1094m
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    ELISA Kit for Human Heat shock cognate 71 kDa protein
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    E1094b
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    CLIA Kit for Human Heat shock cognate 71 kDa protein
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    U1094c
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Heat shock cognate 71 kDa protein
    Cat.:
    U1094r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Heat shock cognate 71 kDa protein
    Cat.:
    U1094h
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    CLIA Kit for Human Heat shock cognate 71 kDa protein
    Cat.:
    U1094b
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Heat shock cognate 71 kDa protein
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    U1094m
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    MSDS:
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    Packing:
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    Polyclonal Antibody for Human Heat shock cognate 71 kDa protein
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    P1094Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Heat shock cognate 71 kDa protein
    Polyclonal Antibody for Human Heat shock cognate 71 kDa protein
    Cat.:
    P1094Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Heat shock cognate 71 kDa protein
    Cat.:
    P1094Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Heat shock cognate 71 kDa protein
    Monoclonal Antibody for Human Heat shock cognate 71 kDa protein
    Monoclonal Antibody for Human Heat shock cognate 71 kDa protein
    Monoclonal Antibody for Human Heat shock cognate 71 kDa protein
    Monoclonal Antibody for Human Heat shock cognate 71 kDa protein
    Monoclonal Antibody for Human Heat shock cognate 71 kDa protein
    Protein for Human Heat shock cognate 71 kDa protein
    Protein for Human Heat shock cognate 71 kDa protein
    Protein for Human Heat shock cognate 71 kDa protein
    Protein for Human Heat shock cognate 71 kDa protein
    Protein for Human Heat shock cognate 71 kDa protein

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Structure and expression of a human gene coding for a 71 kd heat shock 'cognate' protein."
      Dworniczak B.P. , Mirault M.-E.
      Nucleic Acids Res.15:5181-5197(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 1)
    2. 2.
      "Molecular and functional characterization of HSC54, a novel variant of human heat shock cognate protein 70."
      Tsukahara F. , Yoshioka T. , Muraki T.
      Mol. Pharmacol.58:1257-1263(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
    3. 3.
      "Complete coding sequence of human HSC70."
      Niswonger M.L. , Berk L.R. , Srivastava P.K.
      Submitted (2001-02) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Placenta.
      tissue: Skin.
    5. 5.
      Bienvenut W.V. , Waridel P. , Quadroni M.
      Submitted (2009-03) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-49; 57-71; 77-102; 103-155; 160-188; 221-247; 273-311; 326-342; 349-416; 424-447; 452-493; 510-517; 540-550; 570-597 AND 602-646;CLEAVAGE OF INITIATOR METHIONINE;ACETYLATION AT SER-2;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Embryonic kidney.
    6. 6.
      Bienvenut W.V. , Lilla S. , von Kriegsheim A. , Lempens A. , Kolch W. , Bilsland A.E. , Keith W.N.
      Submitted (2010-01) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-49; 57-72; 78-88; 113-188; 221-247; 300-319; 326-342; 349-357; 362-384; 424-447; 452-469; 510-517; 540-550 AND 584-609;CLEAVAGE OF INITIATOR METHIONINE;ACETYLATION AT SER-2;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Colon carcinoma.
      tissue: Ovarian carcinoma.
    7. 7.
      Lubec G. , Vishwanath V. , Chen W.-Q. , Sun Y.
      Submitted (2008-12) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 4-49; 57-71; 77-88; 113-126; 129-155; 160-187; 221-246; 300-311; 329-342; 362-384; 424-447; 540-550 AND 574-583;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Brain.
      tissue: Cajal-Retzius cell.
      tissue: Fetal brain cortex.
    8. 8.
      "Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes."
      Rasmussen H.H. , van Damme J. , Puype M. , Gesser B. , Celis J.E. , Vandekerckhove J.
      Electrophoresis13:960-969(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 50-55; 103-107 AND 580-596
    9. 9.
      "Identification of the 70kD heat shock cognate protein (Hsc70) and alpha-actinin-1 as novel phosphotyrosine-containing proteins in T lymphocytes."
      Egerton M. , Moritz R.L. , Druker B. , Kelso A. , Simpson R.J.
      Biochem. Biophys. Res. Commun.224:666-674(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 77-86; 221-236 AND 302-311
    10. 10.
      "A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity."
      Cloutier P. , Lavallee-Adam M. , Faubert D. , Blanchette M. , Coulombe B.
      PLoS Genet.9:E1003210-E1003210(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 551-567;METHYLATION AT LYS-561;MUTAGENESIS OF LYS-561;IDENTIFICATION BY MASS SPECTROMETRY
    11. 11.
      "Intracellular localization and partial amino acid sequence of a stress-inducible 40-kDa protein in HeLa cells."
      Hattori H. , Liu Y.-C. , Tohnai I. , Ueda M. , Kaneda T. , Kobayashi T. , Tanabe K. , Ohtsuka K.
      Cell Struct. Funct.17:77-86(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
    12. 12.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH BAG1;DOMAIN
    13. 13.
      "Expression and location of Hsp70/Hsc-binding anti-apoptotic protein BAG-1 and its variants in normal tissues and tumor cell lines."
      Takayama S. , Krajewski S. , Krajewska M. , Kitada S. , Zapata J.M. , Kochel K. , Knee D. , Scudiero D. , Tudor G. , Miller G.J. , Miyashita T. , Yamada M. , Reed J.C.
      Cancer Res.58:3116-3131(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH BAG1
    14. 14.
      "HSC70 interactions with SV40 viral proteins differ between permissive and nonpermissive mammalian cells."
      Sainis L. , Angelidis C. , Pagoulatos G.N. , Lazaridis L.
      Cell Stress Chaperones5:132-138(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SV40 VP1
    15. 15.
      "The MSG1 non-DNA-binding transactivator binds to the p300/CBP coactivators, enhancing their functional link to the Smad transcription factors."
      Yahata T. , de Caestecker M.P. , Lechleider R.J. , Andriole S. , Roberts A.B. , Isselbacher K.J. , Shioda T.
      J. Biol. Chem.275:8825-8834(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH CITED1
    16. 16.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;IDENTIFICATION AS LPS RECEPTOR;INTERACTION WITH CXCR4; GDF5 AND HSP90AA1;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    17. 17.
      "A product of the human gene adjacent to parkin is a component of Lewy bodies and suppresses Pael receptor-induced cell death."
      Imai Y. , Soda M. , Murakami T. , Shoji M. , Abe K. , Takahashi R.
      J. Biol. Chem.278:51901-51910(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PACRG
    18. 18.
      "Proteomic identification of proteins conjugated to ISG15 in mouse and human cells."
      Giannakopoulos N.V. , Luo J.K. , Papov V. , Zou W. , Lenschow D.J. , Jacobs B.S. , Borden E.C. , Li J. , Virgin H.W. , Zhang D.E.
      Biochem. Biophys. Res. Commun.336:496-506(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ISGYLATION
    19. 19.
      "Phosphorylation and binding partner analysis of the TSC1-TSC2 complex."
      Nellist M. , Burgers P.C. , van den Ouweland A.M.W. , Halley D.J.J. , Luider T.M.
      Biochem. Biophys. Res. Commun.333:818-826(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TSC2;IDENTIFICATION BY MASS SPECTROMETRY
    20. 20.
      "Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes."
      Chi A. , Valencia J.C. , Hu Z.-Z. , Watabe H. , Yamaguchi H. , Mangini N.J. , Huang H. , Canfield V.A. , Cheng K.C. , Yang F. , Abe R. , Yamagishi S. , Shabanowitz J. , Hearing V.J. , Wu C. , Appella E. , Hunt D.F.
      J. Proteome Res.5:3135-3144(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS]
      tissue: Melanoma.
    21. 21.
      "HERC5 is an IFN-induced HECT-type E3 protein ligase that mediates type I IFN-induced ISGylation of protein targets."
      Wong J.J. , Pung Y.F. , Sze N.S. , Chin K.C.
      Proc. Natl. Acad. Sci. U.S.A.103:10735-10740(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HERC5;ISGYLATION
    22. 22.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN A MRNP GRANULE COMPLEX;IDENTIFICATION BY MASS SPECTROMETRY;SUBCELLULAR LOCATION
    23. 23.
      "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."
      Matsuoka S. , Ballif B.A. , Smogorzewska A. , McDonald E.R. III , Hurov K.E. , Luo J. , Bakalarski C.E. , Zhao Z. , Solimini N. , Lerenthal Y. , Shiloh Y. , Gygi S.P. , Elledge S.J.
      Science316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-153;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic kidney.
    24. 24.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    25. 25.
      "Identification and characterization of a novel nuclear protein complex involved in nuclear hormone receptor-mediated gene regulation."
      Garapaty S. , Xu C.F. , Trojer P. , Mahajan M.A. , Neubert T.A. , Samuels H.H.
      J. Biol. Chem.284:7542-7552(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN A COMPLEX WITH HCFC1; MKI67; C11ORF30; MATR3; ZNF335; TUBB2A; CCAR2; ASCL2; RBBP5 AND WDR5
    26. 26.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    27. 27.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-246; LYS-319; LYS-589; LYS-597 AND LYS-601;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    28. 28.
      "Hsp70 interacts with the retroviral restriction factor TRIM5alpha and assists the folding of TRIM5alpha."
      Hwang C.Y. , Holl J. , Rajan D. , Lee Y. , Kim S. , Um M. , Kwon K.S. , Song B.
      J. Biol. Chem.285:7827-7837(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TRIM5
    29. 29.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION AS A COMPONENT OF THE PRP19-CDC5L COMPLEX;SUBCELLULAR LOCATION
    30. 30.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-362;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    31. 31.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    32. 32.
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    33. 33.
      "The E3 ubiquitin ligase CHIP and the molecular chaperone Hsc70 form a dynamic, tethered complex."
      Smith M.C. , Scaglione K.M. , Assimon V.A. , Patury S. , Thompson A.D. , Dickey C.A. , Southworth D.R. , Paulson H.L. , Gestwicki J.E. , Zuiderweg E.R.
      Biochemistry52:5354-5364(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT;INTERACTION WITH CHIP
    34. 34.
      "Identification and characterization of a novel human methyltransferase modulating Hsp70 function through lysine methylation."
      Jakobsson M.E. , Moen A. , Bousset L. , Egge-Jacobsen W. , Kernstock S. , Melki R. , Falnes P.O.
      J. Biol. Chem.288:27752-27763(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: METHYLATION AT LYS-561;MUTAGENESIS OF LYS-561;INTERACTION WITH METTL21A
    35. 35.
      "Endoplasmic reticulum protein quality control is determined by cooperative interactions between Hsp/c70 protein and the CHIP E3 ligase."
      Matsumura Y. , Sakai J. , Skach W.R.
      J. Biol. Chem.288:31069-31079(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN ERAD;INTERACTION WITH CHIP
    36. 36.
      "High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy."
      Hasson S.A. , Kane L.A. , Yamano K. , Huang C.H. , Sliter D.A. , Buehler E. , Wang C. , Heman-Ackah S.M. , Hessa T. , Guha R. , Martin S.E. , Youle R.J.
      Nature504:291-295(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PARK2
    37. 37.
      "Electrostatic interactions of Hsp-organizing protein tetratricopeptide domains with Hsp70 and Hsp90: computational analysis and protein engineering."
      Kajander T. , Sachs J.N. , Goldman A. , Regan L.
      J. Biol. Chem.284:25364-25374(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.05 ANGSTROMS) OF 1-634
    38. 38.
      "Novel adenosine-derived inhibitors of 70 kDa heat shock protein, discovered through structure-based design."
      Williamson D.S. , Borgognoni J. , Clay A. , Daniels Z. , Dokurno P. , Drysdale M.J. , Foloppe N. , Francis G.L. , Graham C.J. , Howes R. , Macias A.T. , Murray J.B. , Parsons R. , Shaw T. , Surgenor A.E. , Terry L. , Wang Y. , Wood M. , more...
      J. Med. Chem.52:1510-1513(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 4-381 IN COMPLEXES WITH ATP AND ATP ANALOGS
    39. 39.
      "Adenosine-derived inhibitors of 78 kDa glucose regulated protein (Grp78) ATPase: insights into isoform selectivity."
      Macias A.T. , Williamson D.S. , Allen N. , Borgognoni J. , Clay A. , Daniels Z. , Dokurno P. , Drysdale M.J. , Francis G.L. , Graham C.J. , Howes R. , Matassova N. , Murray J.B. , Parsons R. , Shaw T. , Surgenor A.E. , Terry L. , Wang Y. , more...
      J. Med. Chem.54:4034-4041(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS) OF 4-381 IN COMPLEXES WITH ATP ANALOGS
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