IGFBP4 ELISA Kit for Human(Homo sapiens) | EIAab.comIGFBP4 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > IGFBP4(Gene name) > Human

IGFBP4 (Gene name),

Insulin-like growth factor-binding protein 4 (Protein name ), IBP4_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

IGFBP4(IBP4);

Protein name:

Insulin-like growth factor-binding protein 4(IBP-4;IGF-binding protein 4;IGFBP-4);

Alternative:

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Binds IGF2 more than IGF1.

Function:

IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

258

Sequence:

50:

100:

150:

200:

250:

258:

QLADSFRE

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P22692

Pfam:

PF00219

UniGene:

Hs.462998

MIM:

146733

STRING:

9606.ENSP00000269593

SMR:

P22692

KEGG:

hsa:3487

Uniprot:

P22692

FOR

ELISA Kit for Human IBP-4

Cat.:

E0055h

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Manual:

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MSDS:

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Packing:

96T

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ELISA Kit for Human IBP-4

Cat.:

E0055r

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Manual:

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Packing:

96T

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ELISA Kit for Human IBP-4

Cat.:

E0055m

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MSDS:

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Packing:

96T

ELISA Kit for Human IBP-4

Cat.:

E0055b

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MSDS:

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Packing:

96T

ELISA Kit for Human IBP-4

Cat.:

E0055p

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MSDS:

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Packing:

96T

CLIA Kit for Human IBP-4

Cat.:

U0055m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human IBP-4

Cat.:

U0055b

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MSDS:

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Packing:

96T

CLIA Kit for Human IBP-4

Cat.:

U0055p

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MSDS:

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Packing:

96T

CLIA Kit for Human IBP-4

Cat.:

U0055r

Price:

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Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Human IBP-4

Cat.:

U0055h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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Polyclonal Antibody for Human IBP-4

Cat.:

P0055Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human IBP-4

Cat.:

P0055Rb-r

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human IBP-4

Cat.:

P0055Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human IBP-4

Monoclonal Antibody for Human IBP-4

Protein for Human IBP-4

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Molecular cloning of the cDNAs encoding a novel insulin-like growth factor-binding protein from rat and human."
Shimasaki S. , Uchiyama F. , Shimonaka M. , Ling N.
Mol. Endocrinol.4:1451-1458(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Placenta.
2.

"Inhibitory insulin-like growth factor-binding protein: cloning, complete sequence, and physiological regulation."
Latour D. , Mohan S. , Linkhart T.A. , Baylink D.J. , Strong D.D.
Mol. Endocrinol.4:1806-1814(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
3.

"Identification and molecular cloning of two new 30-kDa insulin-like growth factor binding proteins isolated from adult human serum."
Kiefer M.C. , Masiarz F.R. , Bauer D.M. , Zapf J.
J. Biol. Chem.266:9043-9049(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PROTEIN SEQUENCE OF 22-41
tissue: Osteosarcoma.
4.

"Structural and functional analysis of the 5'-flanking region of the human insulin-like growth factor binding protein (IGFBP)-4 gene."
Qin X. , Morales S. , Lee K.-W. , Boonyaratanakornkit V. , Baylink D.J. , Mohan S. , Strong D.D.
Biochim. Biophys. Acta1350:136-140(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
tissue: Placenta.
5.

"Structure and transcription regulation of the human insulin-like growth factor binding protein 4 gene (IGFBP4)."
Zazzi H. , Nikoshkov A. , Hall K. , Luthman H.
Genomics49:401-410(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
6.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue: Uterus.
7.

"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
Submitted (2004-10) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
8.

NIEHS SNPs program
Submitted (2003-10) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
9.

"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
Zody M.C. , Garber M. , Adams D.J. , Sharpe T. , Harrow J. , Lupski J.R. , Nicholson C. , Searle S.M. , Wilming L. , Young S.K. , Abouelleil A. , Allen N.R. , Bi W. , Bloom T. , Borowsky M.L. , Bugalter B.E. , Butler J. , Chang J.L. , more...
Nature440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
10.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
11.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Colon.
12.

"Purification of a colon cancer cell growth inhibitor and its identification as an insulin-like growth factor binding protein."
Culouscou J.-M. , Shoyab M.
Cancer Res.51:2813-2819(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 22-53
tissue: Colon.
13.

"Evidence that the inhibition of TE85 human bone cell proliferation by agents which stimulate cAMP production may in part be mediated by changes in the IGF-II regulatory system."
Mohan S. , Baylink D.J.
Growth Regul.1:110-118(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 22-42;INDUCTION
tissue: Osteosarcoma.
14.

"Structural basis for the regulation of insulin-like growth factors by IGF binding proteins."
Siwanowicz I. , Popowicz G.M. , Wisniewska M. , Huber R. , Kuenkele K.-P. , Lang K. , Engh R.A. , Holak T.A.
Structure13:155-167(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.6 ANGSTROMS) OF 24-103 IN COMPLEX WITH IGF1;DISULFIDE BONDS
15.

"Structural basis for the inhibition of insulin-like growth factors by insulin-like growth factor-binding proteins."
Sitar T. , Popowicz G.M. , Siwanowicz I. , Huber R. , Holak T.A.
Proc. Natl. Acad. Sci. U.S.A.103:13028-13033(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS) OF 22-253 IN COMPLEX WITH IGF1;DISULFIDE BONDS

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