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Index > Protein center > IGFBP5(Gene name) > Human
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  • IGFBP5 (Gene name),
  • Insulin-like growth factor-binding protein 5 (Protein name ),  IBP5_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    IGFBP5(IBP5);
    Protein name:
    Insulin-like growth factor-binding protein 5(IBP-5;IGF-binding protein 5;IGFBP-5);
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    272
    Sequence:
    50:
    MVLLTAVLLL | LAAYAGPAQS | LGSFVHCEPC | DEKALSMCPP | SPLGCELVKE | 
    100:
    PGCGCCMTCA | LAEGQSCGVY | TERCAQGLRC | LPRQDEEKPL | HALLHGRGVC | 
    150:
    LNEKSYREQV | KIERDSREHE | EPTTSEMAEE | TYSPKIFRPK | HTRISELKAE | 
    200:
    AVKKDRRKKL | TQSKFVGGAE | NTAHPRIISA | PEMRQESEQG | PCRRHMEASL | 
    250:
    QELKASPRMV | PRAVYLPNCD | RKGFYKRKQC | KPSRGRKRGI | CWCVDKYGMK | 
    272:
    LPGMEYVDGD | FQCHTFDSSN | VE
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    MIM:
    Pfam:
    UniGene:
    SMR:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human IBP-5
    Cat.:
    E1441h
    Price:
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human IBP-5
    Cat.:
    E1441b
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human IBP-5
    Cat.:
    E1441r
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    ELISA Kit for Human IBP-5
    Cat.:
    E1441m
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    ELISA Kit for Human IBP-5
    Cat.:
    E1441p
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human IBP-5
    Cat.:
    U1441b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human IBP-5
    Cat.:
    U1441h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human IBP-5
    Cat.:
    U1441m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human IBP-5
    Cat.:
    U1441r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human IBP-5
    Cat.:
    U1441p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human IBP-5
    Cat.:
    P1441Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human IBP-5
    Cat.:
    P1441Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human IBP-5
    Cat.:
    P1441Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human IBP-5
    Polyclonal Antibody for Human IBP-5
    Monoclonal Antibody for Human IBP-5
    Monoclonal Antibody for Human IBP-5
    Monoclonal Antibody for Human IBP-5
    Monoclonal Antibody for Human IBP-5
    Monoclonal Antibody for Human IBP-5
    Protein for Human IBP-5
    Protein for Human IBP-5
    Protein for Human IBP-5
    Protein for Human IBP-5
    Protein for Human IBP-5

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    References
    1. 1.
      "Molecular cloning of a new human insulin-like growth factor binding protein."
      Kiefer M.C. , Ioh R.S. , Bauer D.M. , Zapf J.
      Biochem. Biophys. Res. Commun.176:219-225(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Osteosarcoma.
    2. 2.
      "Identification of five different insulin-like growth factor binding proteins (IGFBPs) from adult rat serum and molecular cloning of a novel IGFBP-5 in rat and human."
      Shimasaki S. , Shimonaka M. , Zhang H.-P. , Ling N.
      J. Biol. Chem.266:10646-10653(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Placenta.
    3. 3.
      "Characterization of the chromosomal gene and promoter for human insulin-like growth factor binding protein-5."
      Allander S.V. , Larsson C. , Ehrenborg E. , Suwanichkul A. , Weber G. , Morris S.L. , Bajalica S. , Kiefer M.C. , Luthman H. , Powell D.R.
      J. Biol. Chem.269:10891-10898(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    4. 4.
      Yu W. , Gibbs R.A.
      Submitted (1998-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
    5. 5.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2004-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    6. 6.
      NIEHS SNPs program
      Submitted (2004-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT TRP-138
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
    8. 8.
      "A novel human insulin-like growth factor binding protein secreted by osteoblast-like cells."
      Andress D.L. , Birnbaum R.S.
      Biochem. Biophys. Res. Commun.176:213-218(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 24-43
    9. 9.
      "Isolation and characterization of circulating 13-kDa C-terminal fragments of human insulin-like growth factor binding protein-5."
      Standker L. , Wobst P. , Mark S. , Forssmann W.-G.
      FEBS Lett.441:281-286(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 141-178 AND 209-223;GLYCOSYLATION AT THR-172
      tissue: Plasma.
    10. 10.
      "Defining the disulfide bonds of insulin-like growth factor-binding protein-5 by tandem mass spectrometry with electron transfer dissociation and collision-induced dissociation."
      Nili M. , Mukherjee A. , Shinde U. , David L. , Rotwein P.
      J. Biol. Chem.287:1510-1519(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISULFIDE BONDS;IDENTIFICATION BY MASS SPECTROMETRY
    11. 11.
      "Structure of the IGF-binding domain of the insulin-like growth factor-binding protein-5 (IGFBP-5): implications for IGF and IGF-I receptor interactions."
      Kalus W. , Zweckstetter M. , Renner C. , Sanchez Y. , Georgescu J. , Grol M. , Demuth D. , Schumacher R. , Dony C. , Lang K. , Holak T.A.
      EMBO J.17:6558-6572(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 60-106
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