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Index > Protein center > Ide(Gene name) > Mouse
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  • Ide (Gene name),
  • Insulin-degrading enzyme (Protein name ),  IDE_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Ide;
    Protein name:
    Insulin-degrading enzyme;
    Alternative:
    Insulysin;Insulin protease(Insulinase);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homodimer. Can form higher oligomers.
    Function:
    Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    1019
    Sequence:
    50:
    MRNGLVWLLH | PALPGTLRSI | LGARPPPAKR | LCGFPKQTYS | TMSNPAIQRI | 
    100:
    EDQIVKSPED | KREYRGLELA | NGIKVLLISD | PTTDKSSAAL | DVHIGSLSDP | 
    150:
    PNIPGLSHFC | EHMLFLGTKK | YPKENEYSQF | LSEHAGSSNA | FTSGEHTNYY | 
    200:
    FDVSHEHLEG | ALDRFAQFFL | CPLLDASCKD | REVNAVDSEH | EKNVMNDAWR | 
    250:
    LFQLEKATGN | PKHPFSKFGT | GNKYTLETRP | NQEGIDVREE | LLKFHSTYYS | 
    300:
    SNLMAICVLG | RESLDDLTNL | VVKLFSEVEN | KNVPLPEFPE | HPFQEEHLRQ | 
    350:
    LYKIVPIKDI | RNLYVTFPIP | DLQQYYKSNP | GYYLGHLIGH | EGPGSLLSEL | 
    400:
    KSKGWVNTLV | GGQKEGARGF | MFFIINVDLT | EEGLLHVEDI | ILHMFQYIQK | 
    450:
    LRAEGPQEWV | FQECKDLNAV | AFRFKDKERP | RGYTSKIAGK | LHYYPLNGVL | 
    500:
    TAEYLLEEFR | PDLIDMVLDK | LRPENVRVAI | VSKSFEGKTD | RTEQWYGTQY | 
    550:
    KQEAIPEDVI | QKWQNADLNG | KFKLPTKNEF | IPTNFEILSL | EKDATPYPAL | 
    600:
    IKDTAMSKLW | FKQDDKFFLP | KACLNFEFFS | PFAYVDPLHC | NMAYLYLELL | 
    650:
    KDSLNEYAYA | AELAGLSYDL | QNTIYGMYLS | VKRYNDKQPI | LLKKITEKMA | 
    700:
    TFEIDKKRFE | IIKEAYMRSL | NNFRAEQPHQ | HAMYYLRLLM | TEVAWTKDEL | 
    750:
    KEALDDVTLP | RLKAFIPQLL | SRLHIEALLH | GNITKQAALG | VMQMVEDTLI | 
    800:
    EHAHTKPLLP | SQLVRYREVQ | LPDRGWFVYQ | QRNEVHNNCG | IEIYYQTDMQ | 
    850:
    STSENMFLEL | FCQIISEPCF | NTLRTKEQLG | YIVFSGPRRA | NGIQGLRFII | 
    900:
    QSEKPPHYLE | SRVEAFLITM | EKAIEDMTEE | AFQKHIQALA | IRRLDKPKKL | 
    950:
    SAECAKYWGE | IISQQYNYDR | DNIEVAYLKT | LTKDDIIRFY | QEMLAVDAPR | 
    1000:
    RHKVSVHVLA | REMDSCPVVG | EFPSQNDINL | SEAPPLPQPE | VIHNMTEFKR | 
    1019:
    GLPLFPLVKP | HINFMAAKL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    String:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Insulin-degrading enzyme
    Cat.:
    E1897m
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Mouse Insulin-degrading enzyme
    Cat.:
    E1897h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Mouse Insulin-degrading enzyme
    Cat.:
    E1897r
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    MSDS:
    Please sign in first.
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    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Insulin-degrading enzyme
    Cat.:
    E1897b
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Insulin-degrading enzyme
    Cat.:
    U1897b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Insulin-degrading enzyme
    Cat.:
    U1897r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Insulin-degrading enzyme
    Cat.:
    U1897h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Insulin-degrading enzyme
    Cat.:
    U1897m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Mouse Insulin-degrading enzyme
    Cat.:
    P1897Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Insulin-degrading enzyme
    Cat.:
    P1897Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Insulin-degrading enzyme
    Cat.:
    P1897Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Insulin-degrading enzyme
    Monoclonal Antibody for Mouse Insulin-degrading enzyme
    Monoclonal Antibody for Mouse Insulin-degrading enzyme
    Monoclonal Antibody for Mouse Insulin-degrading enzyme
    Monoclonal Antibody for Mouse Insulin-degrading enzyme
    Protein for Mouse Insulin-degrading enzyme
    Protein for Mouse Insulin-degrading enzyme
    Protein for Mouse Insulin-degrading enzyme
    Protein for Mouse Insulin-degrading enzyme

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Search for PTS1-containing protein in mammals."
      Van Veldhoven P.P.
      Submitted (2000-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Functional relevance of a novel SlyX motif in non-conventional secretion of insulin-degrading enzyme."
      Glebov K. , Schutze S. , Walter J.
      J. Biol. Chem.286:22711-22715(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;IDENTIFICATION OF SLYX MOTIF;MUTAGENESIS OF 853-GLU--TYR-858
    3. 3.
      "Loss of mPer2 increases plasma insulin levels by enhanced glucose-stimulated insulin secretion and impaired insulin clearance in mice."
      Zhao Y. , Zhang Y. , Zhou M. , Wang S. , Hua Z. , Zhang J.
      FEBS Lett.586:1306-1311(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION
    4. 4.
      "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
      Park J. , Chen Y. , Tishkoff D.X. , Peng C. , Tan M. , Dai L. , Xie Z. , Zhang Y. , Zwaans B.M. , Skinner M.E. , Lombard D.B. , Zhao Y.
      Mol. Cell50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUCCINYLATION [LARGE SCALE ANALYSIS] AT LYS-192 AND LYS-697;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
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