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Index > Protein center > IDH2(Gene name) > Human
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  • IDH2 (Gene name),
  • Isocitrate dehydrogenase [NADP], mitochondrial (Protein name ),  IDHP_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    IDH2;
    Protein name:
    Isocitrate dehydrogenase [NADP], mitochondrial(IDH);
    Alternative:
    IDP;ICD-M;Oxalosuccinate decarboxylase;NADP(+)-specific ICDH;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodimer.
    Function:
    Plays a role in intermediary metabolism and energy production. It may tightly associate or interact with the pyruvate dehydrogenase complex.
    Subcellular Location:
    Mitochondrion
    Protein Attributes:
    Sequence length:
    452
    Sequence:
    50:
    MAGYLRVVRS | LCRASGSRPA | WAPAALTAPT | SQEQPRRHYA | DKRIKVAKPV | 
    100:
    VEMDGDEMTR | IIWQFIKEKL | ILPHVDIQLK | YFDLGLPNRD | QTDDQVTIDS | 
    150:
    ALATQKYSVA | VKCATITPDE | ARVEEFKLKK | MWKSPNGTIR | NILGGTVFRE | 
    200:
    PIICKNIPRL | VPGWTKPITI | GRHAHGDQYK | ATDFVADRAG | TFKMVFTPKD | 
    250:
    GSGVKEWEVY | NFPAGGVGMG | MYNTDESISG | FAHSCFQYAI | QKKWPLYMST | 
    300:
    KNTILKAYDG | RFKDIFQEIF | DKHYKTDFDK | NKIWYEHRLI | DDMVAQVLKS | 
    350:
    SGGFVWACKN | YDGDVQSDIL | AQGFGSLGLM | TSVLVCPDGK | TIEAEAAHGT | 
    400:
    VTRHYREHQK | GRPTSTNPIA | SIFAWTRGLE | HRGKLDGNQD | LIRFAQMLEK | 
    450:
    VCVETVESGA | MTKDLAGCIH | GLSNVKLNEH | FLNTTDFLDT | IKSNLDRALG | 
    452:
    RQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    KEGG:
    Pfam:
    SMR:
    MIM:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human IDH
    Cat.:
    E1170h
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    96T
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    ELISA Kit for Human IDH
    Cat.:
    E1170p
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    Packing:
    96T
    ELISA Kit for Human IDH
    Cat.:
    E1170r
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    96T
    ELISA Kit for Human IDH
    Cat.:
    E1170b
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    96T
    ELISA Kit for Human IDH
    Cat.:
    E1170m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human IDH
    Cat.:
    U1170b
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    Packing:
    96T
    CLIA Kit for Human IDH
    Cat.:
    U1170p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human IDH
    Cat.:
    U1170m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human IDH
    Cat.:
    U1170r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human IDH
    Cat.:
    U1170h
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    Please sign in first.
    MSDS:
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    96T
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    Polyclonal Antibody for Human IDH
    Cat.:
    P1170Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human IDH
    Cat.:
    P1170Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human IDH
    Polyclonal Antibody for Human IDH
    Cat.:
    P1170Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human IDH
    Monoclonal Antibody for Human IDH
    Monoclonal Antibody for Human IDH
    Monoclonal Antibody for Human IDH
    Monoclonal Antibody for Human IDH
    Monoclonal Antibody for Human IDH
    Protein for Human IDH
    Protein for Human IDH
    Protein for Human IDH
    Protein for Human IDH
    Protein for Human IDH

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    References
    1. 1.
      Huh T.-L. , Oh I.-U. , Kim Y.O. , Huh J.-W. , Song B.J.
      Submitted (1992-11) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Heart.
    2. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Brain cortex.
      tissue: Heart.
      tissue: Testis.
    3. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Colon.
      tissue: Skin.
    5. 6.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-67; LYS-106; LYS-155; LYS-166; LYS-180; LYS-256; LYS-263; LYS-272; LYS-275; LYS-282 AND LYS-442;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    6. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    7. 8.
      "SIRT3 protein deacetylates isocitrate dehydrogenase 2 (IDH2) and regulates mitochondrial redox status."
      Yu W. , Dittenhafer-Reed K.E. , Denu J.M.
      J. Biol. Chem.287:14078-14086(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION AT LYS-413;MUTAGENESIS OF LYS-413
    8. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS D2HGA2 GLN-140 AND GLY-140
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