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Index > Protein center > IFIT1(Gene name) > Human
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  • IFIT1 (Gene name),
  • Interferon-induced protein with tetratricopeptide repeats 1 (Protein name ),  IFIT1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    IFIT1(G10P1;IFI56;IFNAI1;ISG56);
    Protein name:
    Interferon-induced protein with tetratricopeptide repeats 1(IFIT-1);
    Alternative:
    Interferon-induced 56 kDa protein(IFI-56K);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    N/A
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    478
    Sequence:
    50:
    MSTNGDDHQV | KDSLEQLRCH | FTWELSIDDD | EMPDLENRVL | DQIEFLDTKY | 
    100:
    SVGIHNLLAY | VKHLKGQNEE | ALKSLKEAEN | LMQEEHDNQA | NVRSLVTWGN | 
    150:
    FAWMYYHMGR | LAEAQTYLDK | VENICKKLSN | PFRYRMECPE | IDCEEGWALL | 
    200:
    KCGGKNYERA | KACFEKVLEV | DPENPESSAG | YAISAYRLDG | FKLATKNHKP | 
    250:
    FSLLPLRQAV | RLNPDNGYIK | VLLALKLQDE | GQEAEGEKYI | EEALANMSSQ | 
    300:
    TYVFRYAAKF | YRRKGSVDKA | LELLKKALQE | TPTSVLLHHQ | IGLCYKAQMI | 
    350:
    QIKEATKGQP | RGQNREKLDK | MIRSAIFHFE | SAVEKKPTFE | VAHLDLARMY | 
    400:
    IEAGNHRKAE | ENFQKLLCMK | PVVEETMQDI | HFHYGRFQEF | QKKSDVNAII | 
    450:
    HYLKAIKIEQ | ASLTRDKSIN | SLKKLVLRKL | RRKALDLESL | SLLGFVYKLE | 
    478:
    GNMNEALEYY | ERALRLAADF | ENSVRQGP
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    MIM:
    String:
    SMR:
    Pfam:
    KEGG:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human IFIT-1
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    E14985h
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    ELISA Kit for Human IFIT-1
    Cat.:
    E14985m
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    MSDS:
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    Packing:
    96T
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    CLIA Kit for Human IFIT-1
    Cat.:
    U14985m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human IFIT-1
    Cat.:
    U14985h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Human IFIT-1
    Polyclonal Antibody for Human IFIT-1
    Monoclonal Antibody for Human IFIT-1
    Monoclonal Antibody for Human IFIT-1
    Protein for Human IFIT-1
    Protein for Human IFIT-1

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    Precision
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Molecular cloning, full-length sequence and preliminary characterization of a 56-kDa protein induced by human interferons."
      Wathelet M. , Moutschen S. , Defilippi P. , Cravador A. , Collet M. , Huez G. , Content J.
      Eur. J. Biochem.155:11-17(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);INDUCTION
    2. 2.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Small intestine.
      tissue: Synovium.
    4. 4.
      "The DNA sequence and comparative analysis of human chromosome 10."
      Deloukas P. , Earthrowl M.E. , Grafham D.V. , Rubenfield M. , French L. , Steward C.A. , Sims S.K. , Jones M.C. , Searle S. , Scott C. , Howe K. , Hunt S.E. , Andrews T.D. , Gilbert J.G.R. , Swarbreck D. , Ashurst J.L. , Taylor A. , Battles J. , more...
      Nature429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Prostate.
    7. 7.
      "Interferon-induced 56,000 Mr protein and its mRNA in human cells: molecular cloning and partial sequence of the cDNA."
      Chebath J. , Merlin G. , Metz R. , Benech P. , Revel M.
      Nucleic Acids Res.11:1213-1226(1983) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 413-478
    8. 8.
      "New inducers revealed by the promoter sequence analysis of two interferon-activated human genes."
      Wathelet M.G. , Clauss I.M. , Nols C.B. , Content J. , Huez G.A.
      Eur. J. Biochem.169:313-321(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-2
    9. 9.
      "The IFI-56K and IFI-54K interferon-inducible human genes belong to the same gene family."
      Wathelet M.G. , Clauss I.M. , Content J. , Huez G.A.
      FEBS Lett.231:164-171(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SIMILARITY TO IFI-54K
    10. 10.
      "Human ISG15 conjugation targets both IFN-induced and constitutively expressed proteins functioning in diverse cellular pathways."
      Zhao C. , Denison C. , Huibregtse J.M. , Gygi S.P. , Krug R.M.
      Proc. Natl. Acad. Sci. U.S.A.102:10200-10205(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ISGYLATION
    11. 11.
      "Induction and mode of action of the viral stress-inducible murine proteins, P56 and P54."
      Terenzi F. , Pal S. , Sen G.C.
      Virology340:116-124(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH EIF3E
    12. 12.
      "Interferon-inducible protein, P56, inhibits HPV DNA replication by binding to the viral protein E1."
      Terenzi F. , Saikia P. , Sen G.C.
      EMBO J.27:3311-3321(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH E1 PROTEINS OF HPV TYPES 11; 18 AND 31
    13. 13.
      "ISG56 is a negative-feedback regulator of virus-triggered signaling and cellular antiviral response."
      Li Y. , Li C. , Xue P. , Zhong B. , Mao A.P. , Ran Y. , Chen H. , Wang Y.Y. , Yang F. , Shu H.B.
      Proc. Natl. Acad. Sci. U.S.A.106:7945-7950(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH TMEM173/MITA;PHOSPHORYLATION
    14. 14.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    15. 15.
      "A novel interaction between interferon-inducible protein p56 and ribosomal protein L15 in gastric cancer cells."
      Hsu Y.A. , Lin H.J. , Sheu J.J. , Shieh F.K. , Chen S.Y. , Lai C.H. , Tsai F.J. , Wan L. , Chen B.H.
      DNA Cell Biol.30:671-679(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RPL15
    16. 16.
      "The interferon stimulated gene 54 promotes apoptosis."
      Stawowczyk M. , Van Scoy S. , Kumar K.P. , Reich N.C.
      J. Biol. Chem.286:7257-7266(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH IFIT2
    17. 17.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
    18. 18.
      "ISG56 and IFITM1 proteins inhibit hepatitis C virus replication."
      Raychoudhuri A. , Shrivastava S. , Steele R. , Kim H. , Ray R. , Ray R.B.
      J. Virol.85:12881-12889(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    19. 19.
      "Where, in antiviral defense, does IFIT1 fit?"
      Ablasser A. , Hornung V.
      Nat. Immunol.12:588-590(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON FUNCTION
    20. 20.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;INTERACTION WITH IFIT2 AND IFIT3;RNA-BINDING
    21. 21.
      "Structural basis for viral 5'-PPP-RNA recognition by human IFIT proteins."
      Abbas Y.M. , Pichlmair A. , Gorna M.W. , Superti-Furga G. , Nagar B.
      Nature494:60-64(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF 7-279;FUNCTION;RNA-BINDING;MUTAGENESIS OF ASP-34; ARG-38; GLN-42; LYS-151; TYR-157; ARG-187 AND ARG-255
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