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Index > Protein center > IFNA1(Gene name) > Human
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  • IFNA1 (Gene name),
  • Interferon alpha-1/13 (Protein name ),  IFNA1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    IFNA1;
    Protein name:
    Interferon alpha-1/13(IFN-alpha-1/13);
    Alternative:
    Interferon alpha-D(LeIF D);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    189
    Sequence:
    50:
    MASPFALLMV | LVVLSCKSSC | SLGCDLPETH | SLDNRRTLML | LAQMSRISPS | 
    100:
    SCLMDRHDFG | FPQEEFDGNQ | FQKAPAISVL | HELIQQIFNL | FTTKDSSAAW | 
    150:
    DEDLLDKFCT | ELYQQLNDLE | ACVMQEERVG | ETPLMNADSI | LAVKKYFRRI | 
    189:
    TLYLTEKKYS | PCAWEVVRAE | IMRSLSLSTN | LQERLRRKE
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    KEGG:
    UniGene:
    MIM:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human IFN-alpha-1/13
    Cat.:
    E0033h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human IFN-alpha-1/13
    Cat.:
    E0033c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human IFN-alpha-1/13
    Cat.:
    E0033m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human IFN-alpha-1/13
    Cat.:
    E0033r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human IFN-alpha-1/13
    Cat.:
    U0033r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human IFN-alpha-1/13
    Cat.:
    U0033m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human IFN-alpha-1/13
    Cat.:
    U0033h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human IFN-alpha-1/13
    Cat.:
    U0033c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Human IFN-alpha-1/13
    Cat.:
    P0033Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human IFN-alpha-1/13
    Cat.:
    P0033Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human IFN-alpha-1/13
    Cat.:
    P0033Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human IFN-alpha-1/13
    Monoclonal Antibody for Human IFN-alpha-1/13
    Monoclonal Antibody for Human IFN-alpha-1/13
    Monoclonal Antibody for Human IFN-alpha-1/13
    Monoclonal Antibody for Human IFN-alpha-1/13
    Protein for Human IFN-alpha-1/13
    Protein for Human IFN-alpha-1/13
    Protein for Human IFN-alpha-1/13
    Protein for Human IFN-alpha-1/13

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "The nucleotide sequence of a cloned human leukocyte interferon cDNA."
      Mantei N. , Schwarzstein M. , Streuli M. , Panem S. , Nagata S. , Weissmann C.
      Gene10:1-10(1980) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Human leukocyte and fibroblast interferons are structurally related."
      Taniguchi T. , Mantei N. , Schwarzstein M. , Nagata S. , Muramatsu M. , Weissmann C.
      Nature285:547-549(1980) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "The structure of eight distinct cloned human leukocyte interferon cDNAs."
      Goeddel D.V. , Leung D.W. , Dull T.J. , Gross M. , Lawn R.M. , McCandliss R. , Seeburg P.H. , Ullrich A. , Yelverton E. , Gray P.W.
      Nature290:20-26(1981) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    4. 4.
      "Two non-allelic human interferon alpha genes with identical coding regions."
      Todokoro K. , Kioussis D. , Weissmann C.
      EMBO J.3:1809-1812(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    6. 6.
      "Two distinct families of human and bovine interferon-alpha genes are coordinately expressed and encode functional polypeptides."
      Capon D.J. , Shepard H.M. , Goeddel D.V.
      Mol. Cell. Biol.5:768-779(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    7. 7.
      "Novel cis-active structures in the coding region mediate CRM1-dependent nuclear export of IFN-alpha 1 mRNA."
      Kimura T. , Hashimoto I. , Nishizawa M. , Ito S. , Yamada H.
      Med. Mol. Morphol.43:145-157(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    8. 8.
      Rostoks N.
      Submitted (1993-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT ALA-10
    9. 9.
      NIEHS SNPs program
      Submitted (2005-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS ALA-10; VAL-137 AND GLY-163
    10. 10.
      "DNA sequence and analysis of human chromosome 9."
      Humphray S.J. , Oliver K. , Hunt A.R. , Plumb R.W. , Loveland J.E. , Howe K.L. , Andrews T.D. , Searle S. , Hunt S.E. , Scott C.E. , Jones M.C. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Ashwell R.I.S. , Babbage A.K. , Babbage S. , Bagguley C.L. , more...
      Nature429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    12. 12.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT ALA-10
      tissue: Cerebellum.
    13. 13.
      "Formation of genes coding for hybrid proteins by recombination between related, cloned genes in E. coli."
      Weber H. , Weissmann C.
      Nucleic Acids Res.11:5661-5669(1983) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 24-189
    14. 14.
      Chen H.H. , Yu X.B.
      Submitted (2001-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 24-189
      tissue: Leukocyte.
    15. 15.
      "Purification and characterization of multiple components of human lymphoblastoid interferon-alpha."
      Zoon K.C. , Miller D. , Bekisz J. , zur Nedden D. , Enterline J.C. , Nguyen N.Y. , Hu R.-Q.
      J. Biol. Chem.267:15210-15216(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 24-59;FUNCTION
    16. 16.
      "Identification of nine interferon-alpha subtypes produced by Sendai virus-induced human peripheral blood leucocytes."
      Nyman T.A. , Toeloe H. , Parkkinen J. , Kalkkinen N.
      Biochem. J.329:295-302(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 24-58
    17. 17.
      "IFN-alpha-1a gene is the major variant in the North American population."
      Hussain M. , Ni D. , Gill D. , Liao M.-J.
      J. Interferon Cytokine Res.20:763-768(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: POLYMORPHISM
    18. 18.
      "Structural insights into a human anti-IFN antibody exerting therapeutic potential for systemic lupus erythematosus."
      Ouyang S. , Gong B. , Li J.Z. , Zhao L.X. , Wu W. , Zhang F.S. , Sun L. , Wang S.J. , Pan M. , Li C. , Liang W. , Shaw N. , Zheng J. , Zhao G.P. , Wang Y. , Liu Z.J. , Liang M.
      J. Mol. Med.90:837-846(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF 24-189 IN COMPLEX WITH ANTIBODY;DISULFIDE BOND
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