Protein name:
Insulin-like growth factor I (IGF-I) ;
Alternative:
Somatomedin ;
Organism:
Dog (Canis familiarisCanis lupus familiaris).
General Annotation
Function:
The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake.
Subcellular Location:
Secreted
Protein Attributes:
50:
MGKISSLPTQ | LFKCCFCDFL | KVKMHTVSSS | HLFYLALCLL | TFPSPATAGP |
100:
ETLCGAELVD | ALQFVCGDRG | FYFNKPTGYG | SSSRRAPQTG | IVDECCFRSC |
150:
DLRRLEMYCA | PLKPAKSARS | VRAQRHTDMP | KAQKEVHLKN | ASRGSAGNKN |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Rabbit
Pig
Mouse
Human
Dog
Chicken
Bovine
Polyclonal Antibody for Dog IGF-I
Polyclonal Antibody for Dog IGF-I
Polyclonal Antibody for Dog IGF-I
Polyclonal Antibody for Dog IGF-I
Polyclonal Antibody for Dog IGF-I
Polyclonal Antibody for Dog IGF-I
Polyclonal Antibody for Dog IGF-I
Polyclonal Antibody for Dog IGF-I
Monoclonal Antibody for Dog IGF-I
Monoclonal Antibody for Dog IGF-I
Monoclonal Antibody for Dog IGF-I
Monoclonal Antibody for Dog IGF-I
Monoclonal Antibody for Dog IGF-I
Monoclonal Antibody for Dog IGF-I
Monoclonal Antibody for Dog IGF-I
Monoclonal Antibody for Dog IGF-I
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
Staten N.R.
Submitted (2005-03) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Synovium .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 30-151
3.
"A single IGF1 allele is a major determinant of small size in dogs."
Sutter N.B.
,
Bustamante C.D.
,
Chase K.
,
Gray M.M.
,
Zhao K.
,
Zhu L.
,
Padhukasahasram B.
,
Karlins E.
,
Davis S.
,
Jones P.G.
,
Quignon P.
,
Johnson G.S.
,
Parker H.G.
,
Fretwell N.
,
Mosher D.S.
,
Lawler D.F.
,
Satyaraj E.
,
Nordborg M.
,
Lark K.G.
,
Wayne R.K.
,
Ostrander E.A.
more...
Science316:112-115(2007)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : POLYMORPHISM