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Index > Protein center > IL24(Gene name) > Human
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  • IL24 (Gene name),
  • Interleukin-24 (Protein name ),  IL24_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    IL24(MDA7;ST16);
    Protein name:
    Interleukin-24(IL-24);
    Alternative:
    Suppression of tumorigenicity 16 protein;Melanoma differentiation-associated gene 7 protein(MDA-7);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Function:
    Has antiproliferative properties on melanoma cells and may contribute to terminal cell differentiation.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    206
    Sequence:
    50:
    MNFQQRLQSL | WTLARPFCPP | LLATASQMQM | VVLPCLGFTL | LLWSQVSGAQ | 
    100:
    GQEFHFGPCQ | VKGVVPQKLW | EAFWAVKDTM | QAQDNITSAR | LLQQEVLQNV | 
    150:
    SDAESCYLVH | TLLEFYLKTV | FKNYHNRTVE | VRTLKSFSTL | ANNFVLIVSQ | 
    200:
    LQPSQENEMF | SIRDSAHRRF | LLFRRAFKQL | DVEAALTKAL | GEVDILLTWM | 
    206:
    QKFYKL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    KEGG:
    SMR:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human IL-24
    Cat.:
    E2064h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human IL-24
    Cat.:
    E2064m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human IL-24
    Cat.:
    E2064r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human IL-24
    Cat.:
    U2064r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human IL-24
    Cat.:
    U2064m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human IL-24
    Cat.:
    U2064h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Human IL-24
    Cat.:
    P2064Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human IL-24
    Cat.:
    P2064Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human IL-24
    Cat.:
    P2064Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human IL-24
    Monoclonal Antibody for Human IL-24
    Monoclonal Antibody for Human IL-24
    Protein for Human IL-24
    Protein for Human IL-24
    Protein for Human IL-24

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    Precision
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    Linearity
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    References
    1. 1.
      "Subtraction hybridization identifies a novel melanoma differentiation associated gene, mda-7, modulated during human melanoma differentiation, growth and progression."
      Jiang H. , Lin J.J. , Su Z.-Z. , Goldstein N.I. , Fisher P.B.
      Oncogene11:2477-2486(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Melanoma.
    2. 2.
      "The human MDA-7 gene."
      Peat J. , Kube D. , Eskdale J. , Jueliger S. , Gallagher G.
      Submitted (2000-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      "Genomic structure, chromosomal localization and expression profile of a novel melanoma differentiation associated (mda-7) gene with cancer specific growth suppressing and apoptosis inducing properties."
      Huang E.Y. , Madireddi M.T. , Gopalkrishnan R.V. , Leszczyniecka M. , Su Z.-Z. , Lebedeva I.V. , Kang D. , Jiang H. , Lin J.J. , Alexandre D. , Chen Y. , Vozhilla N. , Mei M.X. , Christiansen K.A. , Sivo F. , Goldstein N.I. , Mhashilkar A.B. , Chada S. , more...
      Oncogene20:7051-7063(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT HIS-124
      tissue: Fibroblast.
    4. 4.
      "Loss of novel mda-7 splice variant (mda-7s) expression is associated with metastatic melanoma."
      Allen M. , Pratscher B. , Roka F. , Krepler C. , Wacheck V. , Schofer C. , Pehamberger H. , Muller M. , Lucas T.
      J. Invest. Dermatol.123:583-588(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 4)
    5. 5.
      SeattleSNPs variation discovery resource
      Submitted (2001-11) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS HIS-124; ARG-125 AND LEU-131
    6. 6.
      "Alternative splicing of IL-24 in melanocytes by deletion of exons 3 and 5."
      Allen M. , Pratscher B. , Krepler C. , Frei K. , Schofer C. , Pehamberger H. , Muller M. , Lucas T.
      Int. J. Immunogenet.32:375-378(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3);ALTERNATIVE SPLICING
    7. 7.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
    8. 8.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    9. 9.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Lung.
    10. 10.
      "Signal peptide prediction based on analysis of experimentally verified cleavage sites."
      Zhang Z. , Henzel W.J.
      Protein Sci.13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 52-66
    11. 11.
      "The cancer growth suppressor gene mda-7 selectively induces apoptosis in human breast cancer cells and inhibits tumor growth in nude mice."
      Su Z.-Z. , Madireddi M.T. , Lin J.J. , Young C.S.H. , Kitada S. , Reed J.C. , Goldstein N.I. , Fisher P.B.
      Proc. Natl. Acad. Sci. U.S.A.95:14400-14405(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION
    12. 12.
      "Critical role of lysine 123 in the ubiquitin-mediated degradation of MDA-7/IL-24."
      Tian H. , Li L. , Zhang B. , Di J. , Chen F. , Li H. , Liu J. , Pei D. , Zheng J.
      J. Interferon Cytokine Res.32:575-582(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: UBIQUITINATION AT LYS-122
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