IL31RA ELISA Kit for Human(Homo sapiens) | EIAab.comIL31RA ELISA Kit for Human(Homo sapiens)

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IL31RA (Gene name),

Interleukin-31 receptor subunit alpha (Protein name ), IL31R_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

IL31RA(UNQ6368/PRO21073/PRO21384;CRL3;GPL);

Protein name:

Interleukin-31 receptor subunit alpha(IL-31 receptor subunit alpha;IL-31R subunit alpha;IL-31R-alpha;IL-31RA);

Alternative:

GLM-R(hGLM-R);Cytokine receptor-like 3;ZcytoR17;Gp130-like monocyte receptor(Gp130-like receptor);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Heterodimer with OSMR. Interacts with JAK1 and STAT3.

Function:

Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity.

Subcellular Location:

Cell membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

732

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

732:

EEGAPNPYLK | NSVTAREFLV | SEKLPEHTKG | EV

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

hsa:133396

UniGene:

Hs.55378

String:

Q8NI17

SMR:

Q8NI17

MIM:

609510

Pfam:

PF00041

Uniprot:

Q8NI17

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ELISA Kit for Human IL-31 receptor subunit alpha

Cat.:

E0331h

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96T

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ELISA Kit for Human IL-31 receptor subunit alpha

Cat.:

E0331m

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Human IL-31 receptor subunit alpha

Cat.:

U0331h

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Manual:

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MSDS:

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96T

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CLIA Kit for Human IL-31 receptor subunit alpha

Cat.:

U0331m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human IL-31 receptor subunit alpha

Cat.:

P0331Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human IL-31 receptor subunit alpha

Cat.:

P0331Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human IL-31 receptor subunit alpha

Protein for Human IL-31 receptor subunit alpha

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"A novel type I cytokine receptor is expressed on monocytes, signals proliferation, and activates STAT-3 and STAT-5."
Ghilardi N. , Li J. , Hongo J.-A. , Yi S. , Gurney A. , De Sauvage F.J.
J. Biol. Chem.277:16831-16836(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;TISSUE SPECIFICITY;INDUCTION
2.

"Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice."
Dillon S.R. , Sprecher C. , Hammond A. , Bilsborough J. , Rosenfeld-Franklin M. , Presnell S.R. , Haugen H.S. , Maurer M. , Harder B. , Johnston J. , Bort S. , Mudri S. , Kuijper J.L. , Bukowski T. , Shea P. , Dong D.L. , Dasovich M. , Grant F.J. , more...
Nat. Immunol.5:752-760(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2; 3; 4 AND 5);FUNCTION;OLIGOMERIZATION;TISSUE SPECIFICITY;INDUCTION
3.

"A novel soluble type 1 cytokine receptor."
Zhang W. , Wan T. , He L. , Yuan Z. , Cao X.
Submitted (1998-11) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 7)
4.

"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Clark H.F. , Gurney A.L. , Abaya E. , Baker K. , Baldwin D.T. , Brush J. , Chen J. , Chow B. , Chui C. , Crowley C. , Currell B. , Deuel B. , Dowd P. , Eaton D. , Foster J.S. , Grimaldi C. , Gu Q. , Hass P.E. , more...
Genome Res.13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 8)
5.

"The DNA sequence and comparative analysis of human chromosome 5."
Schmutz J. , Martin J. , Terry A. , Couronne O. , Grimwood J. , Lowry S. , Gordon L.A. , Scott D. , Xie G. , Huang W. , Hellsten U. , Tran-Gyamfi M. , She X. , Prabhakar S. , Aerts A. , Altherr M. , Bajorek E. , Black S. , more...
Nature431:268-274(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 6)
7.

"Signal peptide prediction based on analysis of experimentally verified cleavage sites."
Zhang Z. , Henzel W.J.
Protein Sci.13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 20-34
8.

"GPL, a novel cytokine receptor related to GP130 and leukemia inhibitory factor receptor."
Diveu C. , Lelievre E. , Perret D. , Lagrue Lak-Hal A.-H. , Froger J. , Guillet C. , Chevalier S. , Rousseau F. , Wesa A. , Preisser L. , Chabbert M. , Gauchat J.-F. , Galy A. , Gascan H. , Morel A.
J. Biol. Chem.278:49850-49859(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ALTERNATIVE SPLICING (ISOFORMS 9; 10; 11 AND 12);FUNCTION;TISSUE SPECIFICITY;INDUCTION;GLYCOSYLATION
9.

"Predominant expression of the long isoform of GP130-like (GPL) receptor is required for interleukin-31 signaling."
Diveu C. , Lagrue Lak-Hal A.-H. , Froger J. , Ravon E. , Grimaud L. , Barbier F. , Hermann J. , Gascan H. , Chevalier S.
Eur. Cytokine Netw.15:291-302(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;MUTAGENESIS OF TYR-639; TYR-670 AND TYR-708
10.

"Characterization of the signaling capacities of the novel gp130-like cytokine receptor."
Dreuw A. , Radtke S. , Pflanz S. , Lippok B.E. , Heinrich P.C. , Hermanns H.M.
J. Biol. Chem.279:36112-36120(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH JAK1 AND STAT3;MUTAGENESIS OF TYR-639; TYR-670 AND TYR-708
11.

"IL-31 is associated with cutaneous lymphocyte antigen-positive skin homing T cells in patients with atopic dermatitis."
Bilsborough J. , Leung D.Y.M. , Maurer M. , Howell M. , Boguniewicz M. , Yao L. , Storey H. , LeCiel C. , Harder B. , Gross J.A.
J. Allergy Clin. Immunol.117:418-425(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION;TISSUE SPECIFICITY
12.

"Novel IL31RA gene mutation and ancestral OSMR mutant allele in familial primary cutaneous amyloidosis."
Lin M.W. , Lee D.D. , Liu T.T. , Lin Y.F. , Chen S.Y. , Huang C.C. , Weng H.Y. , Liu Y.F. , Tanaka A. , Arita K. , Lai-Cheong J. , Palisson F. , Chang Y.T. , Wong C.K. , Matsuura I. , McGrath J.A. , Tsai S.F.
Eur. J. Hum. Genet.18:26-32(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT PLCA2 PHE-489

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