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Index > Protein center > IL5(Gene name) > Human
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  • IL5 (Gene name),
  • Interleukin-5 (Protein name ),  IL5_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    IL5;
    Protein name:
    Interleukin-5(IL-5);
    Alternative:
    Eosinophil differentiation factor;B-cell differentiation factor I;T-cell replacing factor(TRF);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodimer; disulfide-linked.
    Function:
    Factor that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    134
    Sequence:
    50:
    MRMLLHLSLL | ALGAAYVYAI | PTEIPTSALV | KETLALLSTH | RTLLIANETL | 
    100:
    RIPVPVHKNH | QLCTEEIFQG | IGTLESQTVQ | GGTVERLFKN | LSLIKKYIDG | 
    134:
    QKKKCGEERR | RVNQFLDYLQ | EFLGVMNTEW | IIES
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    MIM:
    Pfam:
    String:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human IL-5
    Cat.:
    E0078h
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    MSDS:
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    96T
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    ELISA Kit for Human IL-5
    Cat.:
    E0078m
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human IL-5
    Cat.:
    E0078p
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human IL-5
    Cat.:
    E0078r
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human IL-5
    Cat.:
    E0078b
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human IL-5
    Cat.:
    E0078d
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human IL-5
    Cat.:
    U0078r
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    CLIA Kit for Human IL-5
    Cat.:
    U0078p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human IL-5
    Cat.:
    U0078m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    CLIA Kit for Human IL-5
    Cat.:
    U0078h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    CLIA Kit for Human IL-5
    Cat.:
    U0078d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human IL-5
    Cat.:
    U0078b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human IL-5
    Cat.:
    P0078Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human IL-5
    Polyclonal Antibody for Human IL-5
    Polyclonal Antibody for Human IL-5
    Cat.:
    P0078Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human IL-5
    Cat.:
    P0078Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human IL-5
    Monoclonal Antibody for Human IL-5
    Monoclonal Antibody for Human IL-5
    Monoclonal Antibody for Human IL-5
    Monoclonal Antibody for Human IL-5
    Monoclonal Antibody for Human IL-5
    Monoclonal Antibody for Human IL-5
    Protein for Human IL-5
    Protein for Human IL-5
    Protein for Human IL-5
    Protein for Human IL-5
    Protein for Human IL-5
    Protein for Human IL-5

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    References
    1. 1.
      "Cloning of cDNA for human T-cell replacing factor (interleukin-5) and comparison with the murine homologue."
      Azuma C. , Tanabe T. , Konishi M. , Kinashi T. , Noma T. , Matsuda F. , Yaoita Y. , Takatsu K. , Hammarstroem L. , Smith C.I.E. , Severinson E. , Honjo T.
      Nucleic Acids Res.14:9149-9158(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Molecular cloning and structure of the human interleukin-5 gene."
      Tanabe T. , Konishi M. , Mizuta T. , Noma T. , Honjo T.
      J. Biol. Chem.262:16580-16584(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      "Molecular cloning, nucleotide sequence, and expression of the gene encoding human eosinophil differentiation factor (interleukin 5)."
      Campbell H.D. , Tucker W.Q.J. , Hort Y. , Martinson M.E. , Mayo G. , Clutterbuck E.J. , Sanderson C.J. , Young I.G.
      Proc. Natl. Acad. Sci. U.S.A.84:6629-6633(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    4. 4.
      "Isolation and characterization of lymphokine cDNA clones encoding mouse and human IgA-enhancing factor and eosinophil colony-stimulating factor activities: relationship to interleukin 5."
      Yokota T. , Coffman R.L. , Hagiwara H. , Rennick D.M. , Takebe Y. , Yokota K. , Gemmell L. , Shrader B. , Yang G. , Meyerson P. , Luh J. , Hoy P. , Pene J. , Briere F. , Spits H. , Banchereau J. , de Vries J. , Lee F.D. , more...
      Proc. Natl. Acad. Sci. U.S.A.84:7388-7392(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    5. 5.
      Honjo T. , Takatsu K. , Severinson E.
      Submitted (1992-02) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
    6. 6.
      SeattleSNPs variation discovery resource
      Submitted (2001-02) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    8. 8.
      "Structure of recombinant human interleukin 5 produced by Chinese hamster ovary cells."
      Minamitake Y. , Kodama S. , Katayama T. , Adachi H. , Tanaka S. , Tsujimoto M.
      J. Biochem.107:292-297(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 20-134;DISULFIDE BONDS;GLYCOSYLATION AT THR-22 AND ASN-47;LACK OF GLYCOSYLATION AT ASN-90
    9. 9.
      "Human interleukin-5 expressed in Escherichia coli: assignment of the disulfide bridges of the purified unglycosylated protein."
      Proudfoot A.E.I. , Davies J.G. , Turcatti G. , Wingfield P.T.
      FEBS Lett.283:61-64(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISULFIDE BONDS
    10. 10.
      "A novel dimer configuration revealed by the crystal structure at 2.4-A resolution of human interleukin-5."
      Milburn M.V. , Hassell A.M. , Lambert M.H. , Jordan S.R. , Proudfoot A.E.I. , Graber P. , Wells T.N.C.
      Nature363:172-176(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS);DISULFIDE BONDS
    11. 11.
      "Structure analysis of the IL-5 ligand-receptor complex reveals a wrench-like architecture for IL-5Ralpha."
      Patino E. , Kotzsch A. , Saremba S. , Nickel J. , Schmitz W. , Sebald W. , Mueller T.D.
      Structure19:1864-1875(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.55 ANGSTROMS) OF 19-134 IN COMPLEX WITH IL5RA;DISULFIDE BONDS
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