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Index > Protein center > IL1RL1(Gene name) > Human
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  • IL1RL1 (Gene name),
  • Interleukin-1 receptor-like 1 (Protein name ),  ILRL1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    IL1RL1(DER4;ST2;T1);
    Protein name:
    Interleukin-1 receptor-like 1;
    Alternative:
    Protein ST2;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with MYD88, IRAK1, IRAK4, and TRAF6.
    Function:
    Receptor for interleukin-33 (IL-33), its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Possibly involved in helper T-cell function.
    Subcellular Location:
    Cell membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    556
    Sequence:
    50:
    MGFWILAILT | ILMYSTAAKF | SKQSWGLENE | ALIVRCPRQG | KPSYTVDWYY | 
    100:
    SQTNKSIPTQ | ERNRVFASGQ | LLKFLPAAVA | DSGIYTCIVR | SPTFNRTGYA | 
    150:
    NVTIYKKQSD | CNVPDYLMYS | TVSGSEKNSK | IYCPTIDLYN | WTAPLEWFKN | 
    200:
    CQALQGSRYR | AHKSFLVIDN | VMTEDAGDYT | CKFIHNENGA | NYSVTATRSF | 
    250:
    TVKDEQGFSL | FPVIGAPAQN | EIKEVEIGKN | ANLTCSACFG | KGTQFLAAVL | 
    300:
    WQLNGTKITD | FGEPRIQQEE | GQNQSFSNGL | ACLDMVLRIA | DVKEEDLLLQ | 
    350:
    YDCLALNLHG | LRRHTVRLSR | KNPIDHHSIY | CIIAVCSVFL | MLINVLVIIL | 
    400:
    KMFWIEATLL | WRDIAKPYKT | RNDGKLYDAY | VVYPRNYKSS | TDGASRVEHF | 
    450:
    VHQILPDVLE | NKCGYTLCIY | GRDMLPGEDV | VTAVETNIRK | SRRHIFILTP | 
    500:
    QITHNKEFAY | EQEVALHCAL | IQNDAKVILI | EMEALSELDM | LQAEALQDSL | 
    550:
    QHLMKVQGTI | KWREDHIANK | RSLNSKFWKH | VRYQMPVPSK | IPRKASSLTP | 
    556:
    LAAQKQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    MIM:
    KEGG:
    String:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Interleukin-1 receptor-like 1
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    E13584h
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    ELISA Kit for Human Interleukin-1 receptor-like 1
    Cat.:
    E13584r
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    ELISA Kit for Human Interleukin-1 receptor-like 1
    Cat.:
    E13584m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Interleukin-1 receptor-like 1
    MSDS:
    Please sign in first.
    CLIA Kit for Human Interleukin-1 receptor-like 1
    Cat.:
    U13584h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Interleukin-1 receptor-like 1
    Cat.:
    U13584m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Interleukin-1 receptor-like 1
    Polyclonal Antibody for Human Interleukin-1 receptor-like 1
    Polyclonal Antibody for Human Interleukin-1 receptor-like 1
    Monoclonal Antibody for Human Interleukin-1 receptor-like 1
    Monoclonal Antibody for Human Interleukin-1 receptor-like 1
    Monoclonal Antibody for Human Interleukin-1 receptor-like 1
    Protein for Human Interleukin-1 receptor-like 1
    Protein for Human Interleukin-1 receptor-like 1
    Protein for Human Interleukin-1 receptor-like 1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM B);VARIANT GLU-78
      tissue: Lymphocyte.
    2. 2.
      "Presence and expression of a novel variant form of ST2 gene product in human leukemic cell line UT-7/GM."
      Tominaga S. , Kuroiwa K. , Tago K. , Iwahana H. , Yanagisawa K. , Komatsu N.
      Biochem. Biophys. Res. Commun.264:14-18(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM C);VARIANT GLU-78
    3. 3.
      "The cloning and nucleotide sequence of human ST2L cDNA."
      Li H. , Tago K. , Io K. , Kuroiwa K. , Arai T. , Iwahana H. , Tominaga S. , Yanagisawa K.
      Genomics67:284-290(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM A);VARIANTS GLU-78 AND THR-433
      tissue: Megakaryoblast.
    4. 4.
      Yanagisawa K.
      Submitted (2001-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION TO 433
    5. 5.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS B AND 4)
      tissue: Placenta.
      tissue: Thymus.
    6. 6.
      "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
      Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 8.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM B)
      tissue: Placenta.
    9. 9.
      "Signal peptide prediction based on analysis of experimentally verified cleavage sites."
      Zhang Z. , Henzel W.J.
      Protein Sci.13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 19-33
    10. 10.
      "Tissue distribution and subcellular localization of a variant form of the human ST2 gene product, ST2V."
      Tago K. , Noda T. , Hayakawa M. , Iwahana H. , Yanagisawa K. , Yashiro T. , Tominaga S.
      Biochem. Biophys. Res. Commun.285:1377-1383(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    11. 11.
      "IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST 2 and induces T helper type 2-associated cytokines."
      Schmitz J. , Owyang A. , Oldham E. , Song Y. , Murphy E. , McClanahan T.K. , Zurawski G. , Moshrefi M. , Qin J. , Li X. , Gorman D.M. , Bazan J.F. , Kastelein R.A.
      Immunity23:479-490(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBUNIT
    12. 12.
      "An unappreciated role for RNA surveillance."
      Hillman R.T. , Green R.E. , Brenner S.E.
      Genome Biol.5:R8.1-R8.16(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SPLICE ISOFORM(S) THAT ARE POTENTIAL NMD TARGET(S)
    13. 13.
      "Structural insights into the interaction of IL-33 with its receptors."
      Liu X. , Hammel M. , He Y. , Tainer J.A. , Jeng U.S. , Zhang L. , Wang S. , Wang X.
      Proc. Natl. Acad. Sci. U.S.A.110:14918-14923(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.27 ANGSTROMS) OF 19-321 IN COMPLEX WITH IL33;GLYCOSYLATION AT ASN-95; ASN-140 AND ASN-191;DISULFIDE BONDS
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