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Index > Protein center > IVL(Gene name) > Human
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  • IVL (Gene name),
  • Involucrin (Protein name ),  INVO_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    IVL;
    Protein name:
    Involucrin;
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Directly or indirectly cross-linked to cornifelin (CNFN).
    Function:
    Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia.
    Subcellular Location:
    Cytoplasm Constituent of the scaffolding of the cornified envelope.
    Protein Attributes:
    Sequence length:
    585
    Sequence:
    50:
    MSQQHTLPVT | LSPALSQELL | KTVPPPVNTH | QEQMKQPTPL | PPPCQKVPVE | 
    100:
    LPVEVPSKQE | EKHMTAVKGL | PEQECEQQQK | EPQEQELQQQ | HWEQHEEYQK | 
    150:
    AENPEQQLKQ | EKTQRDQQLN | KQLEEEKKLL | DQQLDQELVK | RDEQLGMKKE | 
    200:
    QLLELPEQQE | GHLKHLEQQE | GQLKHPEQQE | GQLELPEQQE | GQLELPEQQE | 
    250:
    GQLELPEQQE | GQLELPEQQE | GQLELPEQQE | GQLELPQQQE | GQLELSEQQE | 
    300:
    GQLELSEQQE | GQLKHLEHQE | GQLEVPEEQM | GQLKYLEQQE | GQLKHLDQQE | 
    350:
    KQPELPEQQM | GQLKHLEQQE | GQPKHLEQQE | GQLEQLEEQE | GQLKHLEQQE | 
    400:
    GQLEHLEHQE | GQLGLPEQQV | LQLKQLEKQQ | GQPKHLEEEE | GQLKHLVQQE | 
    450:
    GQLKHLVQQE | GQLEQQERQV | EHLEQQVGQL | KHLEEQEGQL | KHLEQQQGQL | 
    500:
    EVPEQQVGQP | KNLEQEEKQL | ELPEQQEGQV | KHLEKQEAQL | ELPEQQVGQP | 
    550:
    KHLEQQEKHL | EHPEQQDGQL | KHLEQQEGQL | KDLEQQKGQL | EQPVFAPAPG | 
    585:
    QVQDIQPALP | TKGEVLLPVE | HQQQKQEVQW | PPKHK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    KEGG:
    String:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Involucrin
    Cat.:
    E1331h
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Involucrin
    MSDS:
    Please sign in first.
    ELISA Kit for Human Involucrin
    MSDS:
    Please sign in first.
    ELISA Kit for Human Involucrin
    Cat.:
    E1331r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human Involucrin
    Cat.:
    E1331m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Involucrin
    Cat.:
    U1331r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Involucrin
    Cat.:
    U1331m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Involucrin
    MSDS:
    Please sign in first.
    CLIA Kit for Human Involucrin
    MSDS:
    Please sign in first.
    CLIA Kit for Human Involucrin
    Cat.:
    U1331h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Human Involucrin
    Cat.:
    P1331Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Involucrin
    Cat.:
    P1331Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Involucrin
    Polyclonal Antibody for Human Involucrin
    Polyclonal Antibody for Human Involucrin
    Cat.:
    P1331Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Involucrin
    Monoclonal Antibody for Human Involucrin
    Monoclonal Antibody for Human Involucrin
    Monoclonal Antibody for Human Involucrin
    Monoclonal Antibody for Human Involucrin
    Protein for Human Involucrin
    Protein for Human Involucrin
    Protein for Human Involucrin
    Protein for Human Involucrin
    Protein for Human Involucrin

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    References
    1. 1.
      "Structure and evolution of the human involucrin gene."
      Eckert R.L. , Green H.
      Cell46:583-589(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS GLN-227; SER-236 AND GLU-237
    2. 2.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANTS GLN-227; SER-236 AND GLU-237
      tissue: Skin.
    4. 4.
      "S100A11, S100A10, annexin I, desmosomal proteins, small proline-rich proteins, plasminogen activator inhibitor-2, and involucrin are components of the cornified envelope of cultured human epidermal keratinocytes."
      Robinson N.A. , Lapic S. , Welter J.F. , Eckert R.L.
      J. Biol. Chem.272:12035-12046(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 281-290
      tissue: Keratinocyte.
    5. 5.
      "Biophysical characterization of involucrin reveals a molecule ideally suited to function as an intermolecular cross-bridge of the keratinocyte cornified envelope."
      Yaffe M.B. , Beegen H. , Eckert R.L.
      J. Biol. Chem.267:12233-12238(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURAL STUDIES
    6. 6.
      "The glutamine residues reactive in transglutaminase-catalyzed cross-linking of involucrin."
      Simon M. , Green H.
      J. Biol. Chem.263:18093-18098(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLN-LYS CROSS-LINK
    7. 7.
      "Ceramides are bound to structural proteins of the human foreskin epidermal cornified cell envelope."
      Marekov L.N. , Steinert P.M.
      J. Biol. Chem.273:17763-17770(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: LIPIDATION
    8. 8.
      "Identification and characterization of a novel component of the cornified envelope, cornifelin."
      Michibata H. , Chiba H. , Wakimoto K. , Seishima M. , Kawasaki S. , Okubo K. , Mitsui H. , Torii H. , Imai Y.
      Biochem. Biophys. Res. Commun.318:803-813(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH INVOLUCRIN
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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