Protein name:
Interferon-stimulated gene 20 kDa protein ;
Alternative:
Estrogen-regulated transcript 45 protein ;Promyelocytic leukemia nuclear body-associated protein ISG20 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Associates with PML and SP100 in the PML NB complex.
Function:
Exonuclease with specificity for single-stranded RNA and, to a lesser extent for DNA. Degrades RNA at a rate that is approximately 35-fold higher than its rate for single-stranded DNA. Involved in the antiviral function of IFN against RNA viruses.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MAGSREVVAM | DCEMVGLGPH | RESGLARCSL | VNVHGAVLYD | KFIRPEGEIT |
100:
DYRTRVSGVT | PQHMVGATPF | AVARLEILQL | LKGKLVVGHD | LKHDFQALKE |
150:
DMSGYTIYDT | STDRLLWREA | KLDHCRRVSL | RVLSERLLHK | SIQNSLLGHS |
181:
SVEDARATME | LYQISQRIRA | RRGLPRLAVS | D
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Pig
ELISA Kit for Human Interferon-stimulated gene 20 kDa protein
ELISA Kit for Human Interferon-stimulated gene 20 kDa protein
ELISA Kit for Human Interferon-stimulated gene 20 kDa protein
CLIA Kit for Human Interferon-stimulated gene 20 kDa protein
CLIA Kit for Human Interferon-stimulated gene 20 kDa protein
CLIA Kit for Human Interferon-stimulated gene 20 kDa protein
Polyclonal Antibody for Human Interferon-stimulated gene 20 kDa protein
Polyclonal Antibody for Human Interferon-stimulated gene 20 kDa protein
Polyclonal Antibody for Human Interferon-stimulated gene 20 kDa protein
Monoclonal Antibody for Human Interferon-stimulated gene 20 kDa protein
Monoclonal Antibody for Human Interferon-stimulated gene 20 kDa protein
Monoclonal Antibody for Human Interferon-stimulated gene 20 kDa protein
Protein for Human Interferon-stimulated gene 20 kDa protein
Protein for Human Interferon-stimulated gene 20 kDa protein
Protein for Human Interferon-stimulated gene 20 kDa protein
R&D Technical Data
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Precision
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Recovery
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);SUBCELLULAR LOCATION;TISSUE SPECIFICITY;IDENTIFICATION IN PML NB COMPLEX;INDUCTION
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY
3.
"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N.
,
Chen X.
,
Rolfs A.
,
Halleck A.
,
Hines L.
,
Eisenstein S.
,
Koundinya M.
,
Raphael J.
,
Moreira D.
,
Kelley T.
,
LaBaer J.
,
Lin Y.
,
Phelan M.
,
Farmer A.
Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
tissue :
B-cell .
tissue :
Brain .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;ENZYME REGULATION
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION;INTERACTION WITH SMN COMPLEX AND SNRNAS
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : REVIEW ON FUNCTION
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
12.
"Antiviral activities of ISG20 in positive-strand RNA virus infections."
Zhou Z.
,
Wang N.
,
Woodson S.E.
,
Dong Q.
,
Wang J.
,
Liang Y.
,
Rijnbrand R.
,
Wei L.
,
Nichols J.E.
,
Guo J.T.
,
Holbrook M.R.
,
Lemon S.M.
,
Li K.
Virology409:175-188(2011)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION IN HCV; HAV AND YFV RESTRICTION;SUBCELLULAR LOCATION
13.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) IN COMPLEX WITH UMP;COFACTOR;MANGANESE-BINDING SITES