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Index > Protein center > ITGB1(Gene name) > Human
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  • ITGB1 (Gene name),
  • Integrin beta-1 (Protein name ),  ITB1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    ITGB1(FNRB;MDF2;MSK12);
    Protein name:
    Integrin beta-1;
    Alternative:
    VLA-4 subunit beta(GPIIA);Fibronectin receptor subunit beta;VLA-4 subunit beta;
    CD:
    CD29;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Heterodimer of an alpha and a beta subunit. Beta-1 associates with either alpha-1, alpha-2, alpha-3, alpha-4, alpha-5, alpha-6, alpha-7, alpha-8, alpha-9, alpha-10, alpha-11 or alpha-V. Binds LGALS3BP and ITGB1BP3, when associated with alpha-7, but not with alpha-5. Interacts with FLNA, FLNB and RANBP9. Isoform Beta-1D interacts with ACE2. Isoform Beta-1A interacts with the C-terminal region of FLNC. Interacts with KRT1 in the presence of GNB2L1 and SRC. Interacts with HIV-1 Tat. Binds to human echoviruses 1 and 8 capsid proteins and acts as a receptor for these viruses. Interacts with RAB21. Interacts (via the cytoplasmic region) with RAB25 (via the hypervariable C-terminal region). Interacts with FGR.
    Function:
    Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha-4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha-4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin alpha-1/beta-1, alpha-2/beta-1, alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin. Integrin alpha-4/beta-1 is a receptor for VCAM1. It recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. Integrin alpha-3/beta-1 is a receptor for epiligrin, thrombospondin and CSPG4. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. Isoform beta-1B interferes with isoform beta-1A resulting in a dominant negative effect on cell adhesion and migration (in vitro). In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. When associated with alpha-7/beta-1 integrin, regulates cell adhesion and laminin matrix deposition. Involved in promoting endothelial cell motility and angiogenesis. May be involved in up-regulation of the activity of kinases such as PKC via binding to KRT1. Together with KRT1 and GNB2L1/RACK1, serves as a platform for SRC activation or inactivation. Plays a mechanistic adhesive role during telophase, required for the successful completion of cytokinesis.
    Subcellular Location:
    Cell membrane Single-pass type I membrane protein Melanosome Cleavage furrow Isoform beta-1B does not localize to focal adhesions. Highly enriched in stage I melanosomes. Located on plasma membrane of neuroblastoma NMB7 cells. In a lung cancer cell line, in prometaphase and metaphase, localizes diffusely at the membrane and in afew intracellular vesicles. In early telophase, detected mainly on the matrix-facing side of the cells. By mid-telophase, concentrated to the ingressing cleavage furrow, mainly to the basal side of the furrow. In late telophase, concentrated to the extending protrusions formed at the opposite ends of the spreading daughter cells, in vesicles at the base of the lamellipodia formed by the separating daughter cells.
    Protein Attributes:
    Sequence length:
    798
    Sequence:
    50:
    MNLQPIFWIG | LISSVCCVFA | QTDENRCLKA | NAKSCGECIQ | AGPNCGWCTN | 
    100:
    STFLQEGMPT | SARCDDLEAL | KKKGCPPDDI | ENPRGSKDIK | KNKNVTNRSK | 
    150:
    GTAEKLKPED | ITQIQPQQLV | LRLRSGEPQT | FTLKFKRAED | YPIDLYYLMD | 
    200:
    LSYSMKDDLE | NVKSLGTDLM | NEMRRITSDF | RIGFGSFVEK | TVMPYISTTP | 
    250:
    AKLRNPCTSE | QNCTSPFSYK | NVLSLTNKGE | VFNELVGKQR | ISGNLDSPEG | 
    300:
    GFDAIMQVAV | CGSLIGWRNV | TRLLVFSTDA | GFHFAGDGKL | GGIVLPNDGQ | 
    350:
    CHLENNMYTM | SHYYDYPSIA | HLVQKLSENN | IQTIFAVTEE | FQPVYKELKN | 
    400:
    LIPKSAVGTL | SANSSNVIQL | IIDAYNSLSS | EVILENGKLS | EGVTISYKSY | 
    450:
    CKNGVNGTGE | NGRKCSNISI | GDEVQFEISI | TSNKCPKKDS | DSFKIRPLGF | 
    500:
    TEEVEVILQY | ICECECQSEG | IPESPKCHEG | NGTFECGACR | CNEGRVGRHC | 
    550:
    ECSTDEVNSE | DMDAYCRKEN | SSEICSNNGE | CVCGQCVCRK | RDNTNEIYSG | 
    600:
    KFCECDNFNC | DRSNGLICGG | NGVCKCRVCE | CNPNYTGSAC | DCSLDTSTCE | 
    650:
    ASNGQICNGR | GICECGVCKC | TDPKFQGQTC | EMCQTCLGVC | AEHKECVQCR | 
    700:
    AFNKGEKKDT | CTQECSYFNI | TKVESRDKLP | QPVQPDPVSH | CKEKDVDDCW | 
    750:
    FYFTYSVNGN | NEVMVHVVEN | PECPTGPDII | PIVAGVVAGI | VLIGLALLLI | 
    798:
    WKLLMIIHDR | REFAKFEKEK | MNAKWDTGEN | PIYKSAVTTV | VNPKYEGK
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    MIM:
    SMR:
    UniGene:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Integrin beta-1
    Cat.:
    E2224h
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    96T
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    ELISA Kit for Human Integrin beta-1
    Cat.:
    E2224b
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human Integrin beta-1
    Cat.:
    E2224m
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    96T
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    ELISA Kit for Human Integrin beta-1
    Cat.:
    E2224c
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    96T
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    ELISA Kit for Human Integrin beta-1
    Cat.:
    E2224r
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    96T
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    ELISA Kit for Human Integrin beta-1
    Cat.:
    E2224p
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Integrin beta-1
    Cat.:
    U2224m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Integrin beta-1
    Cat.:
    U2224p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Integrin beta-1
    Cat.:
    U2224r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Integrin beta-1
    Cat.:
    U2224h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Integrin beta-1
    Cat.:
    U2224c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Integrin beta-1
    Cat.:
    U2224b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Integrin beta-1
    Polyclonal Antibody for Human Integrin beta-1
    Polyclonal Antibody for Human Integrin beta-1
    Polyclonal Antibody for Human Integrin beta-1
    Cat.:
    P2224Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Integrin beta-1
    Cat.:
    P2224Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Integrin beta-1
    Cat.:
    P2224Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Integrin beta-1
    Monoclonal Antibody for Human Integrin beta-1
    Monoclonal Antibody for Human Integrin beta-1
    Monoclonal Antibody for Human Integrin beta-1
    Monoclonal Antibody for Human Integrin beta-1
    Monoclonal Antibody for Human Integrin beta-1
    Protein for Human Integrin beta-1
    Protein for Human Integrin beta-1
    Protein for Human Integrin beta-1
    Protein for Human Integrin beta-1
    Protein for Human Integrin beta-1
    Protein for Human Integrin beta-1

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Placenta.
    2. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Placenta.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Endometrium.
    4. 4.
      "The DNA sequence and comparative analysis of human chromosome 10."
      Deloukas P. , Earthrowl M.E. , Grafham D.V. , Rubenfield M. , French L. , Steward C.A. , Sims S.K. , Jones M.C. , Searle S. , Scott C. , Howe K. , Hunt S.E. , Andrews T.D. , Gilbert J.G.R. , Swarbreck D. , Ashurst J.L. , Taylor A. , Battles J. , more...
      Nature429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Skin.
    7. 7.
      "Expression and functional analysis of a cytoplasmic domain variant of the beta 1 integrin subunit."
      Balzac F. , Belkin A.M. , Koteliansky V.E. , Balabanov Y.V. , Altruda F. , Silengo L. , Tarone G.
      J. Cell Biol.121:171-178(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 717-757;CHARACTERIZATION OF BETA-1B;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    8. 8.
      "Expression of beta 1B integrin isoform in CHO cells results in a dominant negative effect on cell adhesion and motility."
      Balzac F. , Retta S.F. , Albini A. , Melchiorri A. , Koteliansky V.E. , Geuna M. , Silengo L. , Tarone G.
      J. Cell Biol.127:557-565(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 717-757;FUNCTION
    9. 9.
      "A human integrin beta 1 subunit with a unique cytoplasmic domain generated by alternative mRNA processing."
      Altruda F. , Cervella P. , Tarone G. , Botta C. , Balzac F. , Stefanuto G. , Silengo L.
      Gene95:261-266(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);TISSUE SPECIFICITY
      tissue: Skeletal muscle.
    10. 10.
      "An alternative form of the integrin beta 1 subunit with a variant cytoplasmic domain."
      Languino L.R. , Ruoslahti E.
      J. Biol. Chem.267:7116-7120(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 3);SUBCELLULAR LOCATION;TISSUE SPECIFICITY
      tissue: Cervix carcinoma.
    11. 11.
      "Novel isoform of beta 1 integrin expressed in skeletal and cardiac muscle."
      Zhidkova N.I. , Belkin A.M. , Mayne R.
      Biochem. Biophys. Res. Commun.214:279-285(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL NUCLEOTIDE SEQUENCE [GENOMIC DNA];TISSUE SPECIFICITY
      tissue: Skeletal muscle.
    12. 12.
      "A novel beta 1 integrin isoform produced by alternative splicing: unique expression in cardiac and skeletal muscle."
      van der Flier A. , Kuikman I. , Baudoin C. , van der Neut R. , Sonnenberg A.
      FEBS Lett.369:340-344(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 5);TISSUE SPECIFICITY
    13. 13.
      "Identification of beta1C-2, a novel variant of the integrin beta1 subunit generated by utilization of an alternative splice acceptor site in exon C."
      Svineng G. , Faessler R. , Johansson S.
      Biochem. J.330:1255-1263(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL NUCLEOTIDE SEQUENCE (ISOFORM 4);TISSUE SPECIFICITY
    14. 14.
      "Interaction of ACE2 and integrin beta1 in failing human heart."
      Lin Q. , Keller R.S. , Weaver B. , Zisman L.S.
      Biochim. Biophys. Acta1689:175-178(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 775-784 (ISOFORM 5);IDENTIFICATION BY MASS SPECTROMETRY;INTERACTION WITH ACE2
    15. 15.
      "Infection by echoviruses 1 and 8 depends on the alpha 2 subunit of human VLA-2."
      Bergelson J.M. , St John N. , Kawaguchi S. , Chan M. , Stubdal H. , Modlin J. , Finberg R.W.
      J. Virol.67:6847-6852(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HUMAN ECHOVIRUS 1 AND HUMAN ECHOVIRUS 8 CAPSID PROTEINS
    16. 16.
      "Beta 1D integrin displaces the beta 1A isoform in striated muscles: localization at junctional structures and signaling potential in nonmuscle cells."
      Belkin A.M. , Zhidkova N.I. , Balzac F. , Altruda F. , Tomatis D. , Maier A. , Tarone G. , Koteliansky V.E. , Burridge K.
      J. Cell Biol.132:211-226(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
    17. 17.
      "Mac-2 binding protein is a cell-adhesive protein of the extracellular matrix which self-assembles into ring-like structures and binds beta1 integrins, collagens and fibronectin."
      Sasaki T. , Brakebusch C. , Engel J. , Timpl R.
      EMBO J.17:1606-1613(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH LGALS3BP
    18. 18.
      "The Tat protein of human immunodeficiency virus type-1 promotes vascular cell growth and locomotion by engaging the alpha5beta1 and alphavbeta3 integrins and by mobilizing sequestered basic fibroblast growth factor."
      Barillari G. , Sgadari C. , Fiorelli V. , Samaniego F. , Colombini S. , Manzari V. , Modesti A. , Nair B.C. , Cafaro A. , Stuerzl M. , Ensoli B.
      Blood94:663-672(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HIV-1 TAT
    19. 19.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBUNIT;INTERACTION WITH FAP;SUBCELLULAR LOCATION
    20. 20.
      "A novel muscle-specific beta 1 integrin binding protein (MIBP) that modulates myogenic differentiation."
      Li J. , Mayne R. , Wu C.
      J. Cell Biol.147:1391-1398(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NMRK2
      tissue: Heart.
    21. 21.
      "Interaction between krit1 and icap1alpha infers perturbation of integrin beta1-mediated angiogenesis in the pathogenesis of cerebral cavernous malformation."
      Zhang J. , Clatterbuck R.E. , Rigamonti D. , Chang D.D. , Dietz H.C.
      Hum. Mol. Genet.10:2953-2960(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ITGB1BP1
    22. 22.
      "Integrin cytoplasmic domain-associated protein 1alpha (ICAP-1alpha) interacts directly with the metastasis suppressor nm23-H2, and both proteins are targeted to newly formed cell adhesion sites upon integrin engagement."
      Fournier H.N. , Dupe-Manet S. , Bouvard D. , Lacombe M.L. , Marie C. , Block M.R. , Albiges-Rizo C.
      J. Biol. Chem.277:20895-20902(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
    23. 23.
      "Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin (beta) subunits."
      van Der Flier A. , Kuikman I. , Kramer D. , Geerts D. , Kreft M. , Takafuta T. , Shapiro S.S. , Sonnenberg A.
      J. Cell Biol.156:361-376(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FLNA AND FLNB;MUTAGENESIS OF GLY-778 AND ALA-786
    24. 24.
      "The integrin cytoplasmic domain-associated protein ICAP-1 binds and regulates Rho family GTPases during cell spreading."
      Degani S. , Balzac F. , Brancaccio M. , Guazzone S. , Retta S.F. , Silengo L. , Eva A. , Tarone G.
      J. Cell Biol.156:377-387(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ITGB1BP1;MUTAGENESIS OF 786-ALA--VAL-791
    25. 25.
      "Disruption of focal adhesions by integrin cytoplasmic domain-associated protein-1 alpha."
      Bouvard D. , Vignoud L. , Dupe-Manet S. , Abed N. , Fournier H.N. , Vincent-Monegat C. , Retta S.F. , Fassler R. , Block M.R.
      J. Biol. Chem.278:6567-6574(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH ITGB1BP1
    26. 26.
      "RanBPM is a phosphoprotein that associates with the plasma membrane and interacts with the integrin LFA-1."
      Denti S. , Sirri A. , Cheli A. , Rogge L. , Innamorati G. , Putignano S. , Fabbri M. , Pardi R. , Bianchi E.
      J. Biol. Chem.279:13027-13034(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RANBP9
    27. 27.
      "NG2 proteoglycan promotes endothelial cell motility and angiogenesis via engagement of galectin-3 and alpha3beta1 integrin."
      Fukushi J. , Makagiansar I.T. , Stallcup W.B.
      Mol. Biol. Cell15:3580-3590(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ITGA3; LGALS3 AND CSPG4
    28. 28.
      "Myosin-X provides a motor-based link between integrins and the cytoskeleton."
      Zhang H. , Berg J.S. , Li Z. , Wang Y. , Lang P. , Sousa A.D. , Bhaskar A. , Cheney R.E. , Stromblad S.
      Nat. Cell Biol.6:523-531(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MYO10
    29. 29.
      "Phosphorylation of ACAP1 by Akt regulates the stimulation-dependent recycling of integrin beta1 to control cell migration."
      Li J. , Ballif B.A. , Powelka A.M. , Dai J. , Gygi S.P. , Hsu V.W.
      Dev. Cell9:663-673(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH ACAP1;SUBCELLULAR LOCATION
    30. 30.
      "The Z-disc proteins myotilin and FATZ-1 interact with each other and are connected to the sarcolemma via muscle-specific filamins."
      Gontier Y. , Taivainen A. , Fontao L. , Sonnenberg A. , van der Flier A. , Carpen O. , Faulkner G. , Borradori L.
      J. Cell Sci.118:3739-3749(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FLNB AND FLNC
    31. 31.
      "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
      Liu T. , Qian W.-J. , Gritsenko M.A. , Camp D.G. II , Monroe M.E. , Moore R.J. , Smith R.D.
      J. Proteome Res.4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-406
      tissue: Plasma.
    32. 32.
      "Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of beta1-integrins."
      Pellinen T. , Arjonen A. , Vuoriluoto K. , Kallio K. , Fransen J.A.M. , Ivaska J.
      J. Cell Biol.173:767-780(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RAB21
    33. 33.
      "JAM-L-mediated leukocyte adhesion to endothelial cells is regulated in cis by alpha4beta1 integrin activation."
      Luissint A.C. , Lutz P.G. , Calderwood D.A. , Couraud P.O. , Bourdoulous S.
      J. Cell Biol.183:1159-1173(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN LEUKOCYTE TO ENDOTHELIAL CELLS ADHESION;INTERACTION WITH AMICA1
    34. 34.
      "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
      Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
      J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-212; ASN-481 AND ASN-669
      tissue: Liver.
    35. 35.
      "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins."
      Wollscheid B. , Bausch-Fluck D. , Henderson C. , O'Brien R. , Bibel M. , Schiess R. , Aebersold R. , Watts J.D.
      Nat. Biotechnol.27:378-386(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-403; ASN-406 AND ASN-411
      tissue: Leukemic T-cell.
    36. 36.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-777;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    37. 37.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-794;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    38. 38.
      "The glycoprotein B disintegrin-like domain binds beta 1 integrin to mediate cytomegalovirus entry."
      Feire A.L. , Roy R.M. , Manley K. , Compton T.
      J. Virol.84:10026-10037(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HHV-5 GB
    39. 39.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    40. 40.
      "ACAP4 protein cooperates with Grb2 protein to orchestrate epidermal growth factor-stimulated integrin beta1 recycling in cell migration."
      Yu X. , Wang F. , Liu H. , Adams G. , Aikhionbare F. , Liu D. , Cao X. , Fan L. , Hu G. , Chen Y. , Frost A. , Partridge E. , Ding X. , Yao X.
      J. Biol. Chem.286:43735-43747(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ASAP3
    41. 41.
      "Osteoblast mineralization requires beta1 integrin/ICAP-1-dependent fibronectin deposition."
      Brunner M. , Millon-Fremillon A. , Chevalier G. , Nakchbandi I.A. , Mosher D. , Block M.R. , Albiges-Rizo C. , Bouvard D.
      J. Cell Biol.194:307-322(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH FERMT2 AND TLN1;MUTAGENESIS OF VAL-787
    42. 42.
      "Kindlin-2 regulates podocyte adhesion and fibronectin matrix deposition through interactions with phosphoinositides and integrins."
      Qu H. , Tu Y. , Shi X. , Larjava H. , Saleem M.A. , Shattil S.J. , Fukuda K. , Qin J. , Kretzler M. , Wu C.
      J. Cell Sci.124:879-891(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FERMT2
    43. 43.
      "Mechanistic insights into regulated cargo binding by ACAP1 protein."
      Bai M. , Pang X. , Lou J. , Zhou Q. , Zhang K. , Ma J. , Li J. , Sun F. , Hsu V.W.
      J. Biol. Chem.287:28675-28685(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS) OF 758-769 IN COMPLEX WITH ACAP1;INTERACTION WITH ACAP1 AND ITGA5;SUBCELLULAR LOCATION;MUTAGENESIS OF 760-ARG-ARG-761; 762-GLU--PHE-767 AND 768-LYS-GLU-769
    44. 44.
      "Crystal structure of alpha5beta1 integrin ectodomain: atomic details of the fibronectin receptor."
      Nagae M. , Re S. , Mihara E. , Nogi T. , Sugita Y. , Takagi J.
      J. Cell Biol.197:131-140(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.9 ANGSTROMS) OF 21-465 IN COMPLEX WITH ANTIBODY; ITGA5 AND RGD PEPTIDE;DISULFIDE BONDS;GLYCOSYLATION AT ASN-269 AND ASN-406;METAL-BINDING SITES;SUBUNIT
    45. 45.
      "Mechanism for KRIT1 release of ICAP1-mediated suppression of integrin activation."
      Liu W. , Draheim K.M. , Zhang R. , Calderwood D.A. , Boggon T.J.
      Mol. Cell49:719-729(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF 784-798 IN COMPLEX WITH ITGB1BP1;INTERACTION WITH ITGB1BP1;MUTAGENESIS OF THR-788; VAL-790; ASN-792 AND TYR-795
    46. 46.
      "Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes."
      Chi A. , Valencia J.C. , Hu Z.-Z. , Watabe H. , Yamaguchi H. , Mangini N.J. , Huang H. , Canfield V.A. , Cheng K.C. , Yang F. , Abe R. , Yamagishi S. , Shabanowitz J. , Hearing V.J. , Wu C. , Appella E. , Hunt D.F.
      J. Proteome Res.5:3135-3144(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS]
      tissue: Melanoma.
    47. 47.
      "Interaction of integrin beta1 with cytokeratin 1 in neuroblastoma NMB7 cells."
      Chuang N.N. , Huang C.C.
      Biochem. Soc. Trans.35:1292-1294(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH KRT1;SUBCELLULAR LOCATION
    48. 48.
      "Rab25 associates with alpha5beta1 integrin to promote invasive migration in 3D microenvironments."
      Caswell P.T. , Spence H.J. , Parsons M. , White D.P. , Clark K. , Cheng K.W. , Mills G.B. , Humphries M.J. , Messent A.J. , Anderson K.I. , McCaffrey M.W. , Ozanne B.W. , Norman J.C.
      Dev. Cell13:496-510(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RAB25
    49. 49.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
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