ITIH1 ELISA Kit for Human(Homo sapiens) | EIAab.comITIH1 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > ITIH1(Gene name) > Human

ITIH1 (Gene name),

Inter-alpha-trypsin inhibitor heavy chain H1 (Protein name ), ITIH1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

ITIH1(IGHEP1);

Protein name:

Inter-alpha-trypsin inhibitor heavy chain H1(ITI heavy chain H1;ITI-HC1;Inter-alpha-inhibitor heavy chain 1);

Alternative:

Serum-derived hyaluronan-associated protein(SHAP);Inter-alpha-trypsin inhibitor complex component III;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

I-alpha-I plasma protease inhibitors are assembled from one or two heavy chains (H1, H2 or H3) and one light chain, bikunin. Inter-alpha-inhibitor (I-alpha-I) is composed of H1, H2 and bikunin, inter-alpha-like inhibitor (I-alpha-LI) of H2 and bikunin, and pre-alpha-inhibitor (P-alpha-I) of H3 and bikunin.

Function:

Contains a potential peptide which could stimulate a broad spectrum of phagocytotic cells.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

911

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

900:

911:

AYTDYIVPDI | F

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.420257

MIM:

147270

String:

P19827

Pfam:

PF06668

SMR:

P19827

KEGG:

hsa:3697

STRING:

9606.ENSP00000273283

Uniprot:

P19827

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ELISA Kit for Human ITI heavy chain H1

Cat.:

E1141h

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Manual:

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Packing:

96T

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ELISA Kit for Human ITI heavy chain H1

Cat.:

E1141m

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MSDS:

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Packing:

96T

ELISA Kit for Human ITI heavy chain H1

Cat.:

E1141p

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Packing:

96T

ELISA Kit for Human ITI heavy chain H1

Cat.:

E1141b

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MSDS:

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Packing:

96T

CLIA Kit for Human ITI heavy chain H1

Cat.:

U1141p

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MSDS:

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Packing:

96T

CLIA Kit for Human ITI heavy chain H1

Cat.:

U1141h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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CLIA Kit for Human ITI heavy chain H1

Cat.:

U1141b

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human ITI heavy chain H1

Cat.:

U1141m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human ITI heavy chain H1

Cat.:

P1141Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human ITI heavy chain H1

Cat.:

P1141Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human ITI heavy chain H1

Monoclonal Antibody for Human ITI heavy chain H1

Protein for Human ITI heavy chain H1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Human inter-alpha-trypsin inhibitor: full-length cDNA sequence of the heavy chain H1."
Diarra-Mehrpour M. , Bourguignon J. , Bost F. , Sesboue R. , Muschio F. , Sarafan N. , Martin J.-P.
Biochim. Biophys. Acta1132:114-118(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANTS THR-263; VAL-585 AND ARG-595
tissue: Blood.
tissue: Liver.
2.

"Isolation and characterization of the human inter-alpha-trypsin inhibitor heavy-chain H1 gene."
Bost F. , Bourguignon J. , Martin J.-P. , Sesboue R. , Thiberville L. , Diarra-Mehrpour M.
Eur. J. Biochem.218:283-291(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 2 AND 3);VARIANTS VAL-585 AND ARG-595
tissue: Liver.
tissue: Thymus.
4.

"The DNA sequence, annotation and analysis of human chromosome 3."
Muzny D.M. , Scherer S.E. , Kaul R. , Wang J. , Yu J. , Sudbrak R. , Buhay C.J. , Chen R. , Cree A. , Ding Y. , Dugan-Rocha S. , Gill R. , Gunaratne P. , Harris R.A. , Hawes A.C. , Hernandez J. , Hodgson A.V. , Hume J. , more...
Nature440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
7.

"The heavy chains of human plasma inter-alpha-trypsin inhibitor: their isolation, their identification by electrophoresis and partial sequencing. Differential reactivity with concanavalin A."
Malki N. , Balduyck M. , Maes P. , Capon C. , Mizon C. , Han K.K. , Tartar A. , Fournet B. , Mizon J.
Biol. Chem. Hoppe-Seyler373:1009-1018(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 30-34; 117-119; 126-137; 318-329; 342-355 AND 478-501
tissue: Plasma.
8.

"Analysis of inter-alpha-trypsin inhibitor and a novel trypsin inhibitor, pre-alpha-trypsin inhibitor, from human plasma. Polypeptide chain stoichiometry and assembly by glycan."
Enghild J.J. , Thoegersen I.B. , Pizzo S.V. , Salvesen G.
J. Biol. Chem.264:15975-15981(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 35-54; 110-124; 333-347 AND 399-435
tissue: Plasma.
9.

"Two out of the three kinds of subunits of inter-alpha-trypsin inhibitor are structurally related."
Gebhard W. , Schreitmueller T. , Hochstrasser K. , Wachter E.
Eur. J. Biochem.181:571-576(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 75-911 (ISOFORM 1);PARTIAL PROTEIN SEQUENCE
tissue: Liver.
10.

"A serum-derived hyaluronan-associated protein (SHAP) is the heavy chain of the inter alpha-trypsin inhibitor."
Huang L. , Yoneda M. , Kimata K.
J. Biol. Chem.268:26725-26730(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 177-211 AND 387-428;HYALURONAN BINDING
tissue: Serum.
11.

"Isolation and characterization of cDNAs encoding the heavy chain of human inter-alpha-trypsin inhibitor (I alpha TI): unambiguous evidence for multipolypeptide chain structure of I alpha TI."
Salier J.-P. , Diarra-Mehrpour M. , Sesboue R. , Bourguignon J. , Benarous R. , Ohkubo I. , Kurachi S. , Kurachi K. , Martin J.-P.
Proc. Natl. Acad. Sci. U.S.A.84:8272-8276(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 399-723 (ISOFORM 1/2/3)
12.

"cDNA cloning of human inter-alpha-trypsin inhibitor discloses three different proteins."
Schreitmueller T. , Hochstrasser K. , Resinger P.W.M. , Wachter E. , Gebhard W.
Biol. Chem. Hoppe-Seyler368:963-970(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 535-685 (ISOFORM 1/2/3)
13.

"Chondroitin sulphate covalently cross-links the three polypeptide chains of inter-alpha-trypsin inhibitor."
Morelle W. , Capon C. , Balduyck M. , Sautiere P. , Kouach M. , Michalski C. , Fournet B. , Mizon J.
Eur. J. Biochem.221:881-888(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 669-672;COVALENT LINKAGE WITH CHONDROITIN SULFATE
tissue: Plasma.
14.

"Tandem orientation of the inter-alpha-trypsin inhibitor heavy chain H1 and H3 genes."
Diarra-Mehrpour M. , Bourguignon J. , Sarafan N. , Bost F. , Sesbouee R. , Muschio-Bonnet F. , Martin J.-P.
Biochim. Biophys. Acta1219:551-554(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 870-911
15.

"Glycosylation pattern of human inter-alpha-inhibitor heavy chains."
Flahaut C. , Capon C. , Balduyck M. , Ricart G. , Sautiere P. , Mizon J.
Biochem. J.333:749-756(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT ASN-285 AND ASN-588;MASS SPECTROMETRY
16.

"Posttranslational modifications of human inter-alpha-inhibitor: identification of glycans and disulfide bridges in heavy chains 1 and 2."
Olsen E.H.N. , Rahbek-Nielsen H. , Thoegersen I.B. , Roepstorff P. , Enghild J.J.
Biochemistry37:408-416(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT CYS-60; ASN-285; ASN-588 AND THR-653;DISULFIDE BONDS;IDENTIFICATION BY MASS SPECTROMETRY
17.

"Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry."
Zhang H. , Li X.-J. , Martin D.B. , Aebersold R.
Nat. Biotechnol.21:660-666(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT ASN-285
18.

"Screening for N-glycosylated proteins by liquid chromatography mass spectrometry."
Bunkenborg J. , Pilch B.J. , Podtelejnikov A.V. , Wisniewski J.R.
Proteomics4:454-465(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-588
tissue: Plasma.
19.

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-402 AND THR-407;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
20.

"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-750
tissue: Liver.
21.

"A strategy for precise and large scale identification of core fucosylated glycoproteins."
Jia W. , Lu Z. , Fu Y. , Wang H.P. , Wang L.H. , Chi H. , Yuan Z.F. , Zheng Z.B. , Song L.N. , Han H.H. , Liang Y.M. , Wang J.L. , Cai Y. , Zhang Y.K. , Deng Y.L. , Ying W.T. , He S.M. , Qian X.H.
Mol. Cell. Proteomics8:913-923(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT ASN-285
22.

"Molecular basis of inter-alpha-trypsin inhibitor heavy chain H1 (ITIH1) polymorphism."
Ding M. , Umetsu K. , Yuasa I. , Sato M. , Harada A. , Suzuki T.
Hum. Genet.95:435-436(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS VAL-585 AND ARG-595

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