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Index > Protein center > ITLN1(Gene name) > Human
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  • ITLN1 (Gene name),
  • Intelectin-1 (Protein name ),  ITLN1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    ITLN1(UNQ640/PRO1270;INTL;ITLN;LFR);
    Protein name:
    Intelectin-1(ITLN-1);
    Alternative:
    Galactofuranose-binding lectin;Endothelial lectin HL-1;Omentin;Intestinal lactoferrin receptor;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homotrimer; disulfide-linked.
    Function:
    Has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. Increases AKT phosphorylation in the absence and presence of insulin. May play a role in the defense system against microorganisms. May specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner. May be involved in iron metabolism.
    Subcellular Location:
    Cell membrane Lipid-anchor GPI-anchor Secreted Enriched in lipid rafts.
    Protein Attributes:
    Sequence length:
    313
    Sequence:
    50:
    MNQLSFLLFL | IATTRGWSTD | EANTYFKEWT | CSSSPSLPRS | CKEIKDECPS | 
    100:
    AFDGLYFLRT | ENGVIYQTFC | DMTSGGGGWT | LVASVHENDM | RGKCTVGDRW | 
    150:
    SSQQGSKAVY | PEGDGNWANY | NTFGSAEAAT | SDDYKNPGYY | DIQAKDLGIW | 
    200:
    HVPNKSPMQH | WRNSSLLRYR | TDTGFLQTLG | HNLFGIYQKY | PVKYGEGKCW | 
    250:
    TDNGPVIPVV | YDFGDAQKTA | SYYSPYGQRE | FTAGFVQFRV | FNNERAANAL | 
    300:
    CAGMRVTGCN | TEHHCIGGGG | YFPEASPQQC | GDFSGFDWSG | YGTHVGYSSS | 
    313:
    REITEAAVLL | FYR
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    SMR:
    KEGG:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human ITLN-1
    Cat.:
    E0933h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human ITLN-1
    Cat.:
    E0933m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human ITLN-1
    Cat.:
    U0933m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human ITLN-1
    Cat.:
    U0933h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Human ITLN-1
    Cat.:
    P0933Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human ITLN-1
    Cat.:
    P0933Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human ITLN-1
    Monoclonal Antibody for Human ITLN-1
    Protein for Human ITLN-1
    Protein for Human ITLN-1

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Molecular cloning and functional expression of a human intestinal lactoferrin receptor."
      Suzuki Y.A. , Shin K. , Loennerdal B.
      Biochemistry40:15771-15779(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];GPI-ANCHOR;TISSUE SPECIFICITY
      tissue: Small intestine.
    2. 2.
      "Human homologs of the Xenopus oocyte cortical granule lectin XL35."
      Lee J.K. , Schnee J. , Pang M. , Wolfert M. , Baum L.G. , Moremen K.W. , Pierce M.
      Glycobiology11:65-73(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
      tissue: Small intestine.
    3. 3.
      "Human intelectin is a novel soluble lectin that recognizes galactofuranose in carbohydrate chains of bacterial cell wall."
      Tsuji S. , Uehori J. , Matsumoto M. , Suzuki Y. , Matsuhisa A. , Toyoshima K. , Seya T.
      J. Biol. Chem.276:23456-23463(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 19-28;FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;SUBUNIT;GLYCOSYLATION;VARIANT ASP-109
      tissue: Placenta.
    4. 4.
      "The Xenopus laevis cortical granule lectin: cDNA cloning, developmental expression, and identification of the eglectin family of lectins."
      Chang B.Y. , Peavy T.R. , Wardrip N.J. , Hedrick J.L.
      Comp. Biochem. Physiol.137A:115-129(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT PRO-313
    5. 5.
      "Identification of omentin as a novel depot-specific adipokine in human adipose tissue: possible role in modulating insulin action."
      Yang R.-Z. , Lee M.-J. , Hu H. , Pray J. , Wu H.-B. , Hansen B.C. , Shuldiner A.R. , Fried S.K. , McLenithan J.C. , Gong D.-W.
      Am. J. Physiol.290:E1253-E1261(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
      tissue: Adipose tissue.
    6. 6.
      "Human homolog of the Xenopus laevis egg cortical granule lectin."
      Peavy T.R. , Hedrick J.L.
      Submitted (2004-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT PRO-313
      tissue: Ovary.
    7. 7.
      "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
      Clark H.F. , Gurney A.L. , Abaya E. , Baker K. , Baldwin D.T. , Brush J. , Chen J. , Chow B. , Chui C. , Crowley C. , Currell B. , Deuel B. , Dowd P. , Eaton D. , Foster J.S. , Grimaldi C. , Gu Q. , Hass P.E. , more...
      Genome Res.13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    8. 8.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Adipose tissue.
    9. 9.
      "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
      Submitted (2004-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    10. 10.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    12. 12.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Lung.
    13. 13.
      "Differential structure and activity between human and mouse intelectin-1: human intelectin-1 is a disulfide-linked trimer, whereas mouse homologue is a monomer."
      Tsuji S. , Yamashita M. , Nishiyama A. , Shinohara T. , Li Z. , Myrvik Q.N. , Hoffman D.R. , Henriksen R.A. , Shibata Y.
      Glycobiology17:1045-1051(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT;MASS SPECTROMETRY;GLYCOSYLATION;DISULFIDE BOND;MUTAGENESIS OF CYS-31 AND CYS-48
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