Jun ELISA Kit for Mouse(Mus musculus) | EIAab.comJun ELISA Kit for Mouse(Mus musculus)

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Jun (Gene name),

Transcription factor AP-1 (Protein name ), JUN_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Jun;

Protein name:

Transcription factor AP-1;

Alternative:

Activator protein 1(AP1);AH119;V-jun avian sarcoma virus 17 oncogene homolog(Jun A);Proto-oncogene c-Jun;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Heterodimer with either FOS or BATF3 or ATF7 (By similarity). The ATF7/JUN heterodimer is essential for ATF7 transactivation activity. Interacts with SP1, SPIB and TCF20. Interacts with COPS5; the interaction leads indirectly to its phosphorylation. Component of the SMAD3/SMAD4/JUN/FOS/complex which forms at the AP1 promoter site. The SMAD3/SMAD4 heterodimer acts syngernistically with the JUN/FOS heterodimer to activate transcription in response to TGF-beta (By similarity). Interacts (via its basic DNA binding and leucine zipper domains) with SMAD3 (via an N-terminal domain); the interaction is required for TGF-beta-mediated transactivation of the SMAD3/SMAD4/JUN/FOS/complex (By similarity). Interacts with DSIPI; the interaction inhibits the binding of active AP1 to its target DNA. Interacts with HIVEP3 and MYBBP1A. Interacts with RNF187. Binds to HIPK3.

Function:

Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

334

Sequence:

50:

100:

150:

200:

250:

300:

334:

ANMLREQVAQ | LKQKVMNHVN | SGCQLMLTQQ | LQTF

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00170

UniGene:

Mm.275071

String:

P05627

KEGG:

mmu:16476

SMR:

P05627

Uniprot:

P05627

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ELISA Kit for Mouse Transcription factor AP-1

Cat.:

E1292m

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ELISA Kit for Mouse Transcription factor AP-1

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E1292r

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96T

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ELISA Kit for Mouse Transcription factor AP-1

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E1292h

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ELISA Kit for Mouse Transcription factor AP-1

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E1292b

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96T

ELISA Kit for Mouse Transcription factor AP-1

Cat.:

E1292c

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ELISA Kit for Mouse Transcription factor AP-1

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E1292p

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96T

CLIA Kit for Mouse Transcription factor AP-1

Cat.:

U1292c

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96T

CLIA Kit for Mouse Transcription factor AP-1

Cat.:

U1292p

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96T

CLIA Kit for Mouse Transcription factor AP-1

Cat.:

U1292b

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Packing:

96T

CLIA Kit for Mouse Transcription factor AP-1

Cat.:

U1292h

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Mouse Transcription factor AP-1

Cat.:

U1292r

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Looking for manual.

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96T

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CLIA Kit for Mouse Transcription factor AP-1

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U1292m

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96T

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Polyclonal Antibody for Mouse Transcription factor AP-1

Cat.:

P1292Rb-m

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40ug/0.2ml

Polyclonal Antibody for Mouse Transcription factor AP-1

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P1292Rb-h

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Polyclonal Antibody for Mouse Transcription factor AP-1

Cat.:

P1292Rb-r

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Monoclonal Antibody for Mouse Transcription factor AP-1

Protein for Mouse Transcription factor AP-1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"Transcriptional activation of c-jun during the G0/G1 transition in mouse fibroblasts."
Ryseck R.-P. , Hirai S. , Yaniv M. , Bravo R.
Nature334:535-537(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"Induction of proto-oncogene JUN/AP-1 by serum and TPA."
Lamph W.W. , Wamsley P. , Sassone-Corsi P. , Verma I.M.
Nature334:629-631(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
3.

"Induction of protooncogene c-jun by serum growth factors."
Ryder K. , Nathans D.
Proc. Natl. Acad. Sci. U.S.A.85:8464-8467(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Mammary tumor.
5.

"Molecular cloning reveals that the p160 Myb-binding protein is a novel, predominantly nucleolar protein which may play a role in transactivation by Myb."
Tavner F.J. , Simpson R. , Tashiro S. , Favier D. , Jenkins N.A. , Gilbert D.J. , Copeland N.G. , Macmillan E.M. , Lutwyche J. , Keough R.A. , Ishii S. , Gonda T.J.
Mol. Cell. Biol.18:989-1002(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MYBBP1A
6.

"Inhibition of AP-1 by the glucocorticoid-inducible protein GILZ."
Mittelstadt P.R. , Ashwell J.D.
J. Biol. Chem.276:29603-29610(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DSIPI
7.

"Schnurri-3 (KRC) interacts with c-Jun to regulate the IL-2 gene in T cells."
Oukka M. , Wein M.N. , Glimcher L.H.
J. Exp. Med.199:15-24(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HIVEP3;FUNCTION
8.

"Cyclic AMP stimulates SF-1-dependent CYP11A1 expression through homeodomain-interacting protein kinase 3-mediated Jun N-terminal kinase and c-Jun phosphorylation."
Lan H.-C. , Li H.-J. , Lin G. , Lai P.-Y. , Chung B.-C.
Mol. Cell. Biol.27:2027-2036(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;PHOSPHORYLATION BY HIPK3
9.

"The phagosomal proteome in interferon-gamma-activated macrophages."
Trost M. , English L. , Lemieux S. , Courcelles M. , Desjardins M. , Thibault P.
Immunity30:143-154(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-63;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
10.

"Identification of a co-activator that links growth factor signalling to c-Jun/AP-1 activation."
Davies C.C. , Chakraborty A. , Cipriani F. , Haigh K. , Haigh J.J. , Behrens A.
Nat. Cell Biol.12:963-972(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RNF187
11.

"SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
Park J. , Chen Y. , Tishkoff D.X. , Peng C. , Tan M. , Dai L. , Xie Z. , Zhang Y. , Zwaans B.M. , Skinner M.E. , Lombard D.B. , Zhao Y.
Mol. Cell50:919-930(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-56;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Embryonic fibroblast.

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