Protein name:
Kynurenine--oxoglutarate transaminase 1 ;
Alternative:
Glutamine transaminase K (GTK) ;4.4.1.13;Cysteine-S-conjugate beta-lyase ) ;Kynurenine aminotransferase I (KATI) ;2.6.1.64;Glutamine--phenylpyruvate transaminase ) ;Kynurenine--oxoglutarate transaminase I ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Metabolizes the cysteine conjugates of certain halogenated alkenes and alkanes to form reactive metabolites. Catalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond.
Subcellular Location:
Cytoplasm
Protein Attributes:
50:
MAKQLQARRL | DGIDYNPWVE | FVKLASEHDV | VNLGQGFPDF | PPPDFAVEAF |
100:
QHAVSGDFML | NQYTKTFGYP | PLTKILASFF | GELLGQEIDP | LRNVLVTVGG |
150:
YGALFTAFQA | LVDEGDEVII | IEPFFDCYEP | MTMMAGGRPV | FVSLKPGPIQ |
200:
NGELGSSSNW | QLDPMELAGK | FTSRTKALVL | NTPNNPLGKV | FSREELELVA |
250:
SLCQQHDVVC | ITDEVYQWMV | YDGHQHISIA | SLPGMWERTL | TIGSAGKTFS |
300:
ATGWKVGWVL | GPDHIMKHLR | TVHQNSVFHC | PTQSQAAVAE | SFEREQLLFR |
350:
QPSSYFVQFP | QAMQRCRDHM | IRSLQSVGLK | PIIPQGSYFL | ITDISDFKRK |
400:
MPDLPGAVDE | PYDRRFVKWM | IKNKGLVAIP | VSIFYSVPHQ | KHFDHYIRFC |
422:
FVKDEATLQA | MDEKLRKWKV | EL
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
ELISA Kit for Human Kynurenine--oxoglutarate transaminase 1
ELISA Kit for Human Kynurenine--oxoglutarate transaminase 1
ELISA Kit for Human Kynurenine--oxoglutarate transaminase 1
CLIA Kit for Human Kynurenine--oxoglutarate transaminase 1
CLIA Kit for Human Kynurenine--oxoglutarate transaminase 1
CLIA Kit for Human Kynurenine--oxoglutarate transaminase 1
Polyclonal Antibody for Human Kynurenine--oxoglutarate transaminase 1
Polyclonal Antibody for Human Kynurenine--oxoglutarate transaminase 1
Polyclonal Antibody for Human Kynurenine--oxoglutarate transaminase 1
Monoclonal Antibody for Human Kynurenine--oxoglutarate transaminase 1
Monoclonal Antibody for Human Kynurenine--oxoglutarate transaminase 1
Monoclonal Antibody for Human Kynurenine--oxoglutarate transaminase 1
Protein for Human Kynurenine--oxoglutarate transaminase 1
Protein for Human Kynurenine--oxoglutarate transaminase 1
Protein for Human Kynurenine--oxoglutarate transaminase 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue :
Kidney .
2.
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 3)
tissue :
Brain .
tissue :
Muscle .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) IN COMPLEX WITH PYRIDOXAL PHOSPHATE AND PHENYLALANINE;SUBUNIT;COFACTOR
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (1.5 ANGSTROMS) IN COMPLEXES WITH PYRIDOXAL PHOSPHATE AND THE INHIBITORS INDOLEACETIC ACID AND TRIS;FUNCTION;CATALYTIC ACTIVITY;ENZYME REGULATION;COFACTOR