Camk2a ELISA Kit for Rat(Rattus norvegicus) | EIAab.comCamk2a ELISA Kit for Rat(Rattus norvegicus)

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Camk2a (Gene name),

Calcium/calmodulin-dependent protein kinase type II subunit alpha (Protein name ), KCC2A_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Camk2a;

Protein name:

Calcium/calmodulin-dependent protein kinase type II subunit alpha(CaM kinase II subunit alpha;CaMK-II subunit alpha);

Alternative:

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. Interacts with BAALC, MPDZ, SYN1, CAMK2N2 and SYNGAP1.

Function:

CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity.

Subcellular Location:

Cell junction synapse presynaptic cell membrane Cell junction synapse Postsynaptic lipid rafts.

Protein Attributes:

Sequence length:

478

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

478:

ETRVWHRRDG | KWQIVHFHRS | GAPSVLPH

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P11275

UniGene:

Rn.107499

SMR:

P11275

KEGG:

rno:25400

STRING:

10116.ENSRNOP00000025283

Pfam:

PF08332

Uniprot:

P11275

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ELISA Kit for Rat CaM kinase II subunit alpha

Cat.:

E0655h

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96T

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ELISA Kit for Rat CaM kinase II subunit alpha

Cat.:

E0655r

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96T

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ELISA Kit for Rat CaM kinase II subunit alpha

Cat.:

E0655m

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96T

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CLIA Kit for Rat CaM kinase II subunit alpha

Cat.:

U0655r

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Packing:

96T

CLIA Kit for Rat CaM kinase II subunit alpha

Cat.:

U0655h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Rat CaM kinase II subunit alpha

Cat.:

U0655m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Rat CaM kinase II subunit alpha

Cat.:

P0655Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat CaM kinase II subunit alpha

Cat.:

P0655Rb-h

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40ug/0.2ml

Polyclonal Antibody for Rat CaM kinase II subunit alpha

Cat.:

P0655Rb-r

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat CaM kinase II subunit alpha

Protein for Rat CaM kinase II subunit alpha

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Molecular cloning of a brain-specific calcium/calmodulin-dependent protein kinase."
Lin C.R. , Kapiloff M.S. , Durgerian S. , Tatemoto K. , Russo A.F. , Hanson P. , Schulman H. , Rosenfeld M.G.
Proc. Natl. Acad. Sci. U.S.A.84:5962-5966(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"Conserved and variable regions in the subunits of brain type II Ca2+/calmodulin-dependent protein kinase."
Bulleit R.F. , Bennett M.K. , Molloy S.S. , Hurley J.B. , Kennedy M.B.
Neuron1:63-72(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
3.

"Functional analysis of a complementary DNA for the 50-kilodalton subunit of calmodulin kinase II."
Hanley R.M. , Means A.R. , Ono T. , Kemp B.E. , Burgin K.E. , Waxham N. , Kelly P.T.
Science237:293-297(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 132-327
4.

"Sequence analysis and DNA-protein interactions within the 5' flanking region of the Ca2+/calmodulin-dependent protein kinase II alpha-subunit gene."
Sunyer T. , Sahyoun N.
Proc. Natl. Acad. Sci. U.S.A.87:278-282(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-6
5.

"Synaptic vesicle-associated Ca2+/calmodulin-dependent protein kinase II is a binding protein for synapsin I."
Benfenati F. , Valtorta F. , Rubenstein J.L. , Gorelick F.S. , Greengard P. , Czernik A.J.
Nature359:417-420(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 231-236; 238-246 AND 461-476;INTERACTION WITH SYN1
6.

"Ca2+/calmodulin-dependent protein kinase II: identification of threonine-286 as the autophosphorylation site in the alpha subunit associated with the generation of Ca2+-independent activity."
Thiel G. , Czernik A.J. , Gorelick F. , Nairn A.C. , Greengard P.
Proc. Natl. Acad. Sci. U.S.A.85:6337-6341(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 282-299;ENZYME REGULATION;PHOSPHORYLATION AT THR-286
7.

"Characterization of a calmodulin kinase II inhibitor protein in brain."
Chang B.H. , Mukherji S. , Soderling T.R.
Proc. Natl. Acad. Sci. U.S.A.95:10890-10895(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CAMK2N2
8.

"SynGAP-MUPP1-CaMKII synaptic complexes regulate p38 MAP kinase activity and NMDA receptor-dependent synaptic AMPA receptor potentiation."
Krapivinsky G. , Medina I. , Krapivinsky L. , Gapon S. , Clapham D.E.
Neuron43:563-574(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SYNGAP1 AND MPDZ;MUTAGENESIS OF 432-ILE--THR-435;FUNCTION
9.

"BAALC 1-6-8 protein is targeted to postsynaptic lipid rafts by its N-terminal miristoylation and palmitoylation, and interacts with a, but not b, subunit of Ca2+/calmodulin-dependent protein kinase II."
Wang X. , Tian Q.-B. , Okano A. , Sakagami H. , Moon I.S. , Kondo H. , Endo S. , Suzuki T.
J. Neurochem.92:647-659(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH BAALC;SUBCELLULAR LOCATION

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