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Index > Protein center > CKM(Gene name) > Human
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  • CKM (Gene name),
  • Creatine kinase M-type (Protein name ),  KCRM_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    CKM(CKMM);
    Protein name:
    Creatine kinase M-type;
    Alternative:
    M-CK;Creatine kinase M chain;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Dimer of identical or non-identical chains. With MM being the major form in skeletal muscle and myocardium, MB existing in myocardium, and BB existing in many tissues, especially brain.
    Function:
    Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    381
    Sequence:
    50:
    MPFGNTHNKF | KLNYKPEEEY | PDLSKHNNHM | AKVLTLELYK | KLRDKETPSG | 
    100:
    FTVDDVIQTG | VDNPGHPFIM | TVGCVAGDEE | SYEVFKELFD | PIISDRHGGY | 
    150:
    KPTDKHKTDL | NHENLKGGDD | LDPNYVLSSR | VRTGRSIKGY | TLPPHCSRGE | 
    200:
    RRAVEKLSVE | ALNSLTGEFK | GKYYPLKSMT | EKEQQQLIDD | HFLFDKPVSP | 
    250:
    LLLASGMARD | WPDARGIWHN | DNKSFLVWVN | EEDHLRVISM | EKGGNMKEVF | 
    300:
    RRFCVGLQKI | EEIFKKAGHP | FMWNQHLGYV | LTCPSNLGTG | LRGGVHVKLA | 
    350:
    HLSKHPKFEE | ILTRLRLQKR | GTGGVDTAAV | GSVFDVSNAD | RLGSSEVEQV | 
    381:
    QLVVDGVKLM | VEMEKKLEKG | QSIDDMIPAQ | K
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    MIM:
    UniGene:
    KEGG:
    SMR:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human Creatine kinase M-type
    Cat.:
    E0479m
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    96T
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    ELISA Kit for Human Creatine kinase M-type
    Cat.:
    E0479r
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    MSDS:
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    96T
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    ELISA Kit for Human Creatine kinase M-type
    Cat.:
    E0479h
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    96T
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    ELISA Kit for Human Creatine kinase M-type
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    E0479p
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    ELISA Kit for Human Creatine kinase M-type
    MSDS:
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    ELISA Kit for Human Creatine kinase M-type
    Cat.:
    E0479d
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    MSDS:
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    96T
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    ELISA Kit for Human Creatine kinase M-type
    Cat.:
    E0479c
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human Creatine kinase M-type
    Cat.:
    E0479b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Creatine kinase M-type
    Cat.:
    U0479c
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Creatine kinase M-type
    Cat.:
    U0479r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Creatine kinase M-type
    Cat.:
    U0479d
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Creatine kinase M-type
    Cat.:
    U0479m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Creatine kinase M-type
    Cat.:
    U0479p
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Creatine kinase M-type
    Cat.:
    U0479h
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    CLIA Kit for Human Creatine kinase M-type
    Cat.:
    U0479b
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Creatine kinase M-type
    MSDS:
    Please sign in first.
    Polyclonal Antibody for Human Creatine kinase M-type
    Polyclonal Antibody for Human Creatine kinase M-type
    Polyclonal Antibody for Human Creatine kinase M-type
    Cat.:
    P0479Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Creatine kinase M-type
    Cat.:
    P0479Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Creatine kinase M-type
    Polyclonal Antibody for Human Creatine kinase M-type
    Polyclonal Antibody for Human Creatine kinase M-type
    Cat.:
    P0479Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Creatine kinase M-type
    Monoclonal Antibody for Human Creatine kinase M-type
    Monoclonal Antibody for Human Creatine kinase M-type
    Monoclonal Antibody for Human Creatine kinase M-type
    Monoclonal Antibody for Human Creatine kinase M-type
    Monoclonal Antibody for Human Creatine kinase M-type
    Monoclonal Antibody for Human Creatine kinase M-type
    Monoclonal Antibody for Human Creatine kinase M-type
    Monoclonal Antibody for Human Creatine kinase M-type
    Protein for Human Creatine kinase M-type
    Protein for Human Creatine kinase M-type
    Protein for Human Creatine kinase M-type
    Protein for Human Creatine kinase M-type
    Cat.:
    R0479h
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%
    Protein for Human Creatine kinase M-type
    Protein for Human Creatine kinase M-type
    Protein for Human Creatine kinase M-type
    Protein for Human Creatine kinase M-type

    R&D Technical Data
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    12% SDS-PAGE analysis

                   12% SDS-PAGE analysis


    wb1wb2

        Western blot - Anti-CKM antibody

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Isolation and sequence analysis of a full-length cDNA for human M creatine kinase."
      Perryman M.B. , Kerner S.A. , Bohlmeyer T.J. , Roberts R.
      Biochem. Biophys. Res. Commun.140:981-989(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Developmental regulation and tissue-specific expression of the human muscle creatine kinase gene."
      Trask R.V. , Strauss A.W. , Billadello J.J.
      J. Biol. Chem.263:17142-17149(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    4. 4.
      SeattleSNPs variation discovery resource
      Submitted (2004-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS GLY-83; VAL-127 AND ALA-243
    5. 5.
      "The DNA sequence and biology of human chromosome 19."
      Grimwood J. , Gordon L.A. , Olsen A.S. , Terry A. , Schmutz J. , Lamerdin J.E. , Hellsten U. , Goodstein D. , Couronne O. , Tran-Gyamfi M. , Aerts A. , Altherr M. , Ashworth L. , Bajorek E. , Black S. , Branscomb E. , Caenepeel S. , Carrano A.V. , more...
      Nature428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Liver.
    7. 7.
      "Muscle creatine kinase isoenzyme expression in adult human brain."
      Hamburg R.J. , Friedman D.L. , Olson E.N. , Ma T.S. , Cortez M.D. , Goodman C. , Puleo P.R. , Perryman M.B.
      J. Biol. Chem.265:6403-6409(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1-30
      tissue: Brain.
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 257-327
    9. 9.
      "Crystallization and preliminary X-ray analysis of human muscle creatine kinase."
      Tang L. , Zhou H.M. , Lin Z.J.
      Acta Crystallogr. D55:669-670(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.5 ANGSTROMS)
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