Prkca ELISA Kit for Rat(Rattus norvegicus) | EIAab.comPrkca ELISA Kit for Rat(Rattus norvegicus)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > Prkca(Gene name) > Rat

Prkca (Gene name),

Protein kinase C alpha type (Protein name ), KPCA_RAT from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

Prkca(Pkca);

Protein name:

Protein kinase C alpha type(PKC-A;PKC-alpha);

Alternative:

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with ADAP1/CENTA1, CSPG4 and PRKCABP. Binds to SDPR in the presence of phosphatidylserine (By similarity). Interacts with PICK1 (via PDZ domain) (By similarity). Interacts with TRIM41 (By similarity). Recruited in a circadian manner into a nuclear complex which also includes BMAL1 and GNB2L1/RACK1.

Function:

PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.

Subcellular Location:

Cytoplasm Cell membrane Peripheral membrane protein Nucleus

Protein Attributes:

Sequence length:

672

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

672:

SDFEGFSYVN | PQFVHPILQS | AV

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

UniGene:

Rn.207908

SMR:

P05696

UniGene:

Rn.86669

String:

P05696

Pfam:

PF00130

Uniprot:

P05696

FOR

ELISA Kit for Rat PKC-A

Cat.:

E1380m

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Rat PKC-A

Cat.:

E1380b

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Rat PKC-A

Cat.:

E1380r

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Rat PKC-A

Cat.:

E1380h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Rat PKC-A

MSDS:

Please sign in first.

CLIA Kit for Rat PKC-A

Cat.:

U1380b

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat PKC-A

Cat.:

U1380h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Rat PKC-A

MSDS:

Please sign in first.

CLIA Kit for Rat PKC-A

Cat.:

U1380r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat PKC-A

Cat.:

U1380m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Rat PKC-A

Cat.:

P1380Rb-r

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Rat PKC-A

Cat.:

P1380Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Rat PKC-A

Cat.:

P1380Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Rat PKC-A

Protein for Rat PKC-A

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Nucleotide sequences of cDNAs for alpha and gamma subspecies of rat brain protein kinase C."
Ono Y. , Fujii T. , Igarashi K. , Kikkawa U. , Ogita K. , Nishizuka Y.
Nucleic Acids Res.16:5199-5200(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Brain.
2.

"The common structure and activities of four subspecies of rat brain protein kinase C family."
Kikkawa U. , Ogita K. , Ono Y. , Asaoka Y. , Shearman M.S. , Fujii T. , Ase K. , Sekiguchi K. , Igarashi K. , Nishizuka Y.
FEBS Lett.223:212-216(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Brain.
3.

"Targeting of protein kinase Calpha to caveolae."
Mineo C. , Ying Y.-S. , Chapline C. , Jaken S. , Anderson R.G.W.
J. Cell Biol.141:601-610(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SDPR
4.

"Protein kinase C signaling mediates a program of cell cycle withdrawal in the intestinal epithelium."
Frey M.R. , Clark J.A. , Leontieva O. , Uronis J.M. , Black A.R. , Black J.D.
J. Cell Biol.151:763-778(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN CELL CYCLE ARREST
5.

"PKC alpha regulates the hypertrophic growth of cardiomyocytes through extracellular signal-regulated kinase1/2 (ERK1/2)."
Braz J.C. , Bueno O.F. , De Windt L.J. , Molkentin J.D.
J. Cell Biol.156:905-919(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN CARDIAC HYPERTROPHY
6.

"Protein kinase C-alpha-induced hypertrophy of neonatal rat ventricular myocytes."
Vijayan K. , Szotek E.L. , Martin J.L. , Samarel A.M.
Am. J. Physiol.287:H2777-H2789(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN HEART FAILURE;SUBCELLULAR LOCATION
7.

"The molecular heterogeneity of protein kinase C and its implications for cellular regulation."
Nishizuka Y.
Nature334:661-665(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
8.

"Phosphorylation of activation transcription factor-2 at serine 121 by protein kinase c controls c-Jun-mediated activation of transcription."
Yamasaki T. , Takahashi A. , Pan J. , Yamaguchi N. , Yokoyama K.K.
J. Biol. Chem.284:8567-8581(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
9.

"Ca(2+) bridges the C2 membrane-binding domain of protein kinase Calpha directly to phosphatidylserine."
Verdaguer N. , Corbalan-Garcia S. , Ochoa W.F. , Fita I. , Gomez-Fernandez J.C.
EMBO J.18:6329-6338(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.6 ANGSTROMS) OF 155-293 IN COMPLEX WITH PHOSPHATIDYLSERINE
10.

"Structural and mechanistic insights into the association of PKCalpha-C2 domain to PtdIns(4,5)P2."
Guerrero-Valero M. , Ferrer-Orta C. , Querol-Audi J. , Marin-Vicente C. , Fita I. , Gomez-Fernandez J.C. , Verdaguer N. , Corbalan-Garcia S.
Proc. Natl. Acad. Sci. U.S.A.106:6603-6607(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 156-292 IN COMPLEX WITH PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE;MUTAGENESIS OF TYR-195; LYS-209; LYS-211 AND TRP-245;SUBCELLULAR LOCATION

Product Feedback Wall

* Email:
*Comments: