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Index > Protein center > LAMB1(Gene name) > Human
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  • LAMB1 (Gene name),
  • Laminin subunit beta-1 (Protein name ),  LAMB1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    LAMB1;
    Protein name:
    Laminin subunit beta-1;
    Alternative:
    Laminin-1 subunit beta;Laminin B1 chain;Laminin-12 subunit beta;Laminin-10 subunit beta;Laminin-6 subunit beta;Laminin-2 subunit beta;Laminin-8 subunit beta;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Laminin is a complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma), which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long and three short arms with globules at each end. Beta-1 is a subunit of laminin-1 (laminin-111 or EHS laminin), laminin-2 (laminin-211 or merosin), laminin-6 (laminin-311 or K-laminin), laminin-8 (laminin-411), laminin-10 (laminin-511) and laminin-12 (laminin-213).
    Function:
    Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
    Subcellular Location:
    Secreted extracellular space extracellular matrix basement membrane Major component.
    Protein Attributes:
    Sequence length:
    1786
    Sequence:
    50:
    MGLLQLLAFS | FLALCRARVR | AQEPEFSYGC | AEGSCYPATG | DLLIGRAQKL | 
    100:
    SVTSTCGLHK | PEPYCIVSHL | QEDKKCFICN | SQDPYHETLN | PDSHLIENVV | 
    150:
    TTFAPNRLKI | WWQSENGVEN | VTIQLDLEAE | FHFTHLIMTF | KTFRPAAMLI | 
    200:
    ERSSDFGKTW | GVYRYFAYDC | EASFPGISTG | PMKKVDDIIC | DSRYSDIEPS | 
    250:
    TEGEVIFRAL | DPAFKIEDPY | SPRIQNLLKI | TNLRIKFVKL | HTLGDNLLDS | 
    300:
    RMEIREKYYY | AVYDMVVRGN | CFCYGHASEC | APVDGFNEEV | EGMVHGHCMC | 
    350:
    RHNTKGLNCE | LCMDFYHDLP | WRPAEGRNSN | ACKKCNCNEH | SISCHFDMAV | 
    400:
    YLATGNVSGG | VCDDCQHNTM | GRNCEQCKPF | YYQHPERDIR | DPNFCERCTC | 
    450:
    DPAGSQNEGI | CDSYTDFSTG | LIAGQCRCKL | NVEGEHCDVC | KEGFYDLSSE | 
    500:
    DPFGCKSCAC | NPLGTIPGGN | PCDSETGHCY | CKRLVTGQHC | DQCLPEHWGL | 
    550:
    SNDLDGCRPC | DCDLGGALNN | SCFAESGQCS | CRPHMIGRQC | NEVEPGYYFA | 
    600:
    TLDHYLYEAE | EANLGPGVSI | VERQYIQDRI | PSWTGAGFVR | VPEGAYLEFF | 
    650:
    IDNIPYSMEY | DILIRYEPQL | PDHWEKAVIT | VQRPGRIPTS | SRCGNTIPDD | 
    700:
    DNQVVSLSPG | SRYVVLPRPV | CFEKGTNYTV | RLELPQYTSS | DSDVESPYTL | 
    750:
    IDSLVLMPYC | KSLDIFTVGG | SGDGVVTNSA | WETFQRYRCL | ENSRSVVKTP | 
    800:
    MTDVCRNIIF | SISALLHQTG | LACECDPQGS | LSSVCDPNGG | QCQCRPNVVG | 
    850:
    RTCNRCAPGT | FGFGPSGCKP | CECHLQGSVN | AFCNPVTGQC | HCFQGVYARQ | 
    900:
    CDRCLPGHWG | FPSCQPCQCN | GHADDCDPVT | GECLNCQDYT | MGHNCERCLA | 
    950:
    GYYGDPIIGS | GDHCRPCPCP | DGPDSGRQFA | RSCYQDPVTL | QLACVCDPGY | 
    1000:
    IGSRCDDCAS | GYFGNPSEVG | GSCQPCQCHN | NIDTTDPEAC | DKETGRCLKC | 
    1050:
    LYHTEGEHCQ | FCRFGYYGDA | LQQDCRKCVC | NYLGTVQEHC | NGSDCQCDKA | 
    1100:
    TGQCLCLPNV | IGQNCDRCAP | NTWQLASGTG | CDPCNCNAAH | SFGPSCNEFT | 
    1150:
    GQCQCMPGFG | GRTCSECQEL | FWGDPDVECR | ACDCDPRGIE | TPQCDQSTGQ | 
    1200:
    CVCVEGVEGP | RCDKCTRGYS | GVFPDCTPCH | QCFALWDVII | AELTNRTHRF | 
    1250:
    LEKAKALKIS | GVIGPYRETV | DSVERKVSEI | KDILAQSPAA | EPLKNIGNLF | 
    1300:
    EEAEKLIKDV | TEMMAQVEVK | LSDTTSQSNS | TAKELDSLQT | EAESLDNTVK | 
    1350:
    ELAEQLEFIK | NSDIRGALDS | ITKYFQMSLE | AEERVNASTT | EPNSTVEQSA | 
    1400:
    LMRDRVEDVM | MERESQFKEK | QEEQARLLDE | LAGKLQSLDL | SAAAEMTCGT | 
    1450:
    PPGASCSETE | CGGPNCRTDE | GERKCGGPGC | GGLVTVAHNA | WQKAMDLDQD | 
    1500:
    VLSALAEVEQ | LSKMVSEAKL | RADEAKQSAE | DILLKTNATK | EKMDKSNEEL | 
    1550:
    RNLIKQIRNF | LTQDSADLDS | IEAVANEVLK | MEMPSTPQQL | QNLTEDIRER | 
    1600:
    VESLSQVEVI | LQHSAADIAR | AEMLLEEAKR | ASKSATDVKV | TADMVKEALE | 
    1650:
    EAEKAQVAAE | KAIKQADEDI | QGTQNLLTSI | ESETAASEET | LFNASQRISE | 
    1700:
    LERNVEELKR | KAAQNSGEAE | YIEKVVYTVK | QSAEDVKKTL | DGELDEKYKK | 
    1750:
    VENLIAKKTE | ESADARRKAE | MLQNEAKTLL | AQANSKLQLL | KDLERKYEDN | 
    1786:
    QRYLEDKAQE | LARLEGEVRS | LLKDISQKVA | VYSTCL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    MIM:
    UniGene:
    String:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Laminin subunit beta-1
    Cat.:
    E8728h
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human Laminin subunit beta-1
    MSDS:
    Please sign in first.
    ELISA Kit for Human Laminin subunit beta-1
    Cat.:
    E8728m
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Laminin subunit beta-1
    MSDS:
    Please sign in first.
    CLIA Kit for Human Laminin subunit beta-1
    Cat.:
    U8728m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Laminin subunit beta-1
    Cat.:
    U8728h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Laminin subunit beta-1
    Cat.:
    P8728Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Laminin subunit beta-1
    Cat.:
    P8728Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Laminin subunit beta-1
    Monoclonal Antibody for Human Laminin subunit beta-1
    Monoclonal Antibody for Human Laminin subunit beta-1
    Monoclonal Antibody for Human Laminin subunit beta-1
    Protein for Human Laminin subunit beta-1
    Protein for Human Laminin subunit beta-1
    Protein for Human Laminin subunit beta-1

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    Linearity
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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT ARG-1022
    2. 2.
      "Human laminin B1 chain. A multidomain protein with gene (LAMB1) locus in the q22 region of chromosome 7."
      Pikkarainen T. , Eddy R. , Fukushima Y. , Byers M. , Shows T. , Pihlajaniemi T. , Saraste M. , Tryggvason K.
      J. Biol. Chem.262:10454-10462(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT ARG-1022
    3. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Colon.
    4. 5.
      "Isolation of a cDNA clone for the human laminin-B1 chain and its gene localization."
      Jaye M. , Modi W.S. , Ricca G.A. , Mudd R. , Chiu I.M. , O'Brien S.J. , Drohan W.N.
      Am. J. Hum. Genet.41:605-615(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1276-1709
    5. 6.
      "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
      Liu T. , Qian W.-J. , Gritsenko M.A. , Camp D.G. II , Monroe M.E. , Moore R.J. , Smith R.D.
      J. Proteome Res.4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-1279
      tissue: Plasma.
    6. 7.
      "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
      Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
      J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-1279
      tissue: Liver.
    7. 8.
      "Mutations in LAMB1 cause cobblestone brain malformation without muscular or ocular abnormalities."
      Radmanesh F. , Caglayan A.O. , Silhavy J.L. , Yilmaz C. , Cantagrel V. , Omar T. , Rosti B. , Kaymakcalan H. , Gabriel S. , Li M. , Sestan N. , Bilguvar K. , Dobyns W.B. , Zaki M.S. , Gunel M. , Gleeson J.G.
      Am. J. Hum. Genet.92:468-474(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN LIS5;FUNCTION
    8. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] ARG-1022;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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