Protein name:
Lysosome-associated membrane glycoprotein 2 (LAMP-2;Lysosome-associated membrane protein 2) ;
Alternative:
CD107 antigen-like family member B ;
CD:
CD107b ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter-and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens.
Subcellular Location:
Cell membrane
Single-pass type I membrane protein
Endosome membrane
Single-pass type I membrane protein
Lysosome membrane
Single-pass type I membrane protein
This protein shuttles between lysosomes, endosomes, and the plasma membrane.
Protein Attributes:
50:
MVCFRLFPVP | GSGLVLVCLV | LGAVRSYALE | LNLTDSENAT | CLYAKWQMNF |
100:
TVRYETTNKT | YKTVTISDHG | TVTYNGSICG | DDQNGPKIAV | QFGPGFSWIA |
150:
NFTKAASTYS | IDSVSFSYNT | GDNTTFPDAE | DKGILTVDEL | LAIRIPLNDL |
200:
FRCNSLSTLE | KNDVVQHYWD | VLVQAFVQNG | TVSTNEFLCD | KDKTSTVAPT |
250:
IHTTVPSPTT | TPTPKEKPEA | GTYSVNNGND | TCLLATMGLQ | LNITQDKVAS |
300:
VININPNTTH | STGSCRSHTA | LLRLNSSTIK | YLDFVFAVKN | ENRFYLKEVN |
350:
ISMYLVNGSV | FSIANNNLSY | WDAPLGSSYM | CNKEQTVSVS | GAFQINTFDL |
400:
RVQPFNVTQG | KYSTAQDCSA | DDDNFLVPIA | VGAALAGVLI | LVLLAYFIGL |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Chicken
Mouse
ELISA Kit for Human LAMP-2
ELISA Kit for Human LAMP-2
ELISA Kit for Human LAMP-2
ELISA Kit for Human LAMP-2
CLIA Kit for Human LAMP-2
CLIA Kit for Human LAMP-2
CLIA Kit for Human LAMP-2
CLIA Kit for Human LAMP-2
Polyclonal Antibody for Human LAMP-2
Polyclonal Antibody for Human LAMP-2
Polyclonal Antibody for Human LAMP-2
Polyclonal Antibody for Human LAMP-2
Monoclonal Antibody for Human LAMP-2
Monoclonal Antibody for Human LAMP-2
Monoclonal Antibody for Human LAMP-2
Monoclonal Antibody for Human LAMP-2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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Flanigan M.J.
,
Edwards N.J.
,
Bolanos R.
,
Fasulo D.
,
Halldorsson B.V.
,
Hannenhalli S.
,
Turner R.
,
Yooseph S.
,
Lu F.
,
Nusskern D.R.
,
Shue B.C.
,
Zheng X.H.
,
Zhong F.
,
Delcher A.L.
,
Huson D.H.
,
Kravitz S.A.
,
Mouchard L.
,
Reinert K.
,
Remington K.A.
,
Clark A.G.
,
Waterman M.S.
,
Eichler E.E.
,
Adams M.D.
,
Hunkapiller M.W.
,
Myers E.W.
,
Venter J.C.
more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
10.
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM LAMP-2B)
tissue :
Lymph .
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 29-66
12.
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Cited for : PROTEIN SEQUENCE OF 29-43
13.
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Cited for : POLYLACTOSAMINOGLYCANS
14.
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Cited for : GLYCOSYLATION OF HINGE REGION;PROTEIN SEQUENCE OF 187-215
15.
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Cited for : GLYCOSYLATION AT ASN-49 AND ASN-101
16.
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Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-32; ASN-38; ASN-49; ASN-101; ASN-123 AND ASN-257
tissue :
Plasma .
17.
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Cited for : NOMENCLATURE
18.
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Cited for : SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS]
tissue :
Placenta .
19.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-101; ASN-123; ASN-257 AND ASN-356
tissue :
Liver .
20.
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Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
21.
"Glycogen storage diseases presenting as hypertrophic cardiomyopathy."
Arad M.
,
Maron B.J.
,
Gorham J.M.
,
Johnson W.H. Jr.
,
Saul J.P.
,
Perez-Atayde A.R.
,
Spirito P.
,
Wright G.B.
,
Kanter R.J.
,
Seidman C.E.
,
Seidman J.G.
N. Engl. J. Med.352:362-372(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
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Cited for : VARIANT DAND ARG-321
22.
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Cited for : VARIANT DAND ARG-321