Protein name:
Lymphocyte function-associated antigen 3(Ag3);
Alternative:
Surface glycoprotein LFA-3;
CD:
CD58;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.
Subcellular Location:
Isoform 2
Cell membrane
Lipid-anchor
GPI-anchor
Protein Attributes:
50:
MVAGSDAGRA | LGVLSVVCLL | HCFGFISCFS | QQIYGVVYGN | VTFHVPSNVP |
100:
LKEVLWKKQK | DKVAELENSE | FRAFSSFKNR | VYLDTVSGSL | TIYNLTSSDE |
150:
DEYEMESPNI | TDTMKFFLYV | LESLPSPTLT | CALTNGSIEV | QCMIPEHYNS |
200:
HRGLIMYSWD | CPMEQCKRNS | TSIYFKMEND | LPQKIQCTLS | NPLFNTTSSI |
Vaild Sequence:
Related Databases
Uniprot: