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Index > Protein center > Lpl(Gene name) > Rat
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  • Lpl (Gene name),
  • Lipoprotein lipase (Protein name ),  LIPL_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Lpl;
    Protein name:
    Lipoprotein lipase(LPL);
    Alternative:

    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Homodimer (By similarity). Interacts with APOC2; the interaction activates LPL activity in the presence of lipids. Interacts with GPIHBP1.
    Function:
    The primary function of this lipase is the hydrolysis of triglycerides of circulating chylomicrons and very low density lipoproteins (VLDL). Binding to heparin sulfate proteogylcans at the cell surface is vital to the function. The apolipoprotein, APOC2, acts as a coactivator of LPL activity in the presence of lipids on the luminal surface of vascular endothelium.
    Subcellular Location:
    Cell membrane Lipid-anchor GPI-anchor Secreted Locates to the plasma membrane of microvilli of hepatocytes with triacyl-glycerol-rich lipoproteins (TRL). Some of the bound LPL is then internalized and located inside non-coated endocytic vesicles.
    Protein Attributes:
    Sequence length:
    474
    Sequence:
    50:
    MESKALLLVA | LGVWLQSLTA | FRGGVAAADG | GRDFSDIESK | FALRTPEDTA | 
    100:
    EDTCHLIPGL | ADSVSNCHFN | HSSKTFVVIH | GWTVTGMYES | WVPKLVAALY | 
    150:
    KREPDSNVIV | VDWLYRAQQH | YPVSAGYTKL | VGNDVARFIN | WLEEEFNYPL | 
    200:
    DNVHLLGYSL | GAHAAGVAGS | LTNKKVNRIT | GLDPAGPNFE | YAEAPSRLSP | 
    250:
    DDADFVDVLH | TFTRGSPGRS | IGIQKPVGHV | DIYPNGGTFQ | PGCNIGEAIR | 
    300:
    VIAEKGLGDV | DQLVKCSHER | SIHLFIDSLL | NEENPSKAYR | CNSKEAFEKG | 
    350:
    LCLSCRKNRC | NNVGYEINKV | RAKRSSKMYL | KTRSQMPYKV | FHYQVKIHFS | 
    400:
    GTENDKQNNQ | AFEISLYGTV | AESENIPFTL | PEVATNKTYS | FLIYTEVDIG | 
    450:
    ELLMMKLKWK | NDSYFRWSDW | WSSPSFVIEK | IRVKAGETQK | KVIFCAREKV | 
    474:
    SHLQKGKDAA | VFVKCHDKSL | KKSG
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    KEGG:
    UniGene:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Rat LPL
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    E0386h
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    96T
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    ELISA Kit for Rat LPL
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    E0386r
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    96T
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    ELISA Kit for Rat LPL
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    E0386p
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    96T
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    ELISA Kit for Rat LPL
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    E0386m
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    96T
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    ELISA Kit for Rat LPL
    Cat.:
    E0386b
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    Packing:
    96T
    ELISA Kit for Rat LPL
    Cat.:
    E0386c
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat LPL
    Cat.:
    U0386m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat LPL
    Cat.:
    U0386p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat LPL
    Cat.:
    U0386r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat LPL
    Cat.:
    U0386b
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat LPL
    Cat.:
    U0386h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat LPL
    Cat.:
    U0386c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat LPL
    Cat.:
    P0386Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat LPL
    Polyclonal Antibody for Rat LPL
    Polyclonal Antibody for Rat LPL
    Polyclonal Antibody for Rat LPL
    Cat.:
    P0386Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat LPL
    Cat.:
    P0386Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat LPL
    Monoclonal Antibody for Rat LPL
    Monoclonal Antibody for Rat LPL
    Monoclonal Antibody for Rat LPL
    Monoclonal Antibody for Rat LPL
    Monoclonal Antibody for Rat LPL
    Protein for Rat LPL
    Protein for Rat LPL
    Protein for Rat LPL
    Protein for Rat LPL
    Protein for Rat LPL
    Protein for Rat LPL

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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Sprague-Dawley.
      tissue: Testis.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Kidney.
    3. 3.
      "Lipoprotein lipase gene expression in rat adipocytes is regulated by isoproterenol and insulin through different mechanisms."
      Raynolds M.V. , Awald P.D. , Gordon D.F. , Gutierrez-Hartmann A. , Rule D.C. , Wood W.M. , Eckel R.H.
      Mol. Endocrinol.4:1416-1422(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 336-474;INDUCTION
      tissue: Heart.
    4. 4.
      "Lipoprotein lipase is nitrated in vivo after lipopolysaccharide challenge."
      Casanovas A. , Carrascal M. , Abian J. , Lopez-Tejero M.D. , Llobera M.
      Free Radic. Biol. Med.47:1553-1560(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NITRATION AT TYR-121; TYR-191 AND TYR-343;IDENTIFICATION BY MASS SPECTROMETRY
    5. 5.
      "Discovery of lipoprotein lipase pI isoforms and contributions to their characterization."
      Casanovas A. , Carrascal M. , Abian J. , Lopez-Tejero M.D. , Llobera M.
      J. Proteomics72:1031-1039(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY;GLYCOSYLATION
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