Gene name:
LPAR1 (EDG2;LPA1) ;
Protein name:
Lysophosphatidic acid receptor 1 (LPA receptor 1;LPA-1) ;
Alternative:
Lysophosphatidic acid receptor Edg-2 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with RALA and ADRBK1.
Function:
Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Stimulates phospholipase C (PLC) activity in a manner that is dependent on RALA activation.
Subcellular Location:
Cell surface
Cell membrane
Multi-pass membrane protein
Prior to LPA treatment found predominantly at the cell surface but in the presence of LPA co-localizes with RALA in the endocytic vesicles.
Protein Attributes:
50:
MAAISTSIPV | ISQPQFTAMN | EPQCFYNESI | AFFYNRSGKH | LATEWNTVSK |
100:
LVMGLGITVC | IFIMLANLLV | MVAIYVNRRF | HFPIYYLMAN | LAAADFFAGL |
150:
AYFYLMFNTG | PNTRRLTVST | WLLRQGLIDT | SLTASVANLL | AIAIERHITV |
200:
FRMQLHTRMS | NRRVVVVIVV | IWTMAIVMGA | IPSVGWNCIC | DIENCSNMAP |
250:
LYSDSYLVFW | AIFNLVTFVV | MVVLYAHIFG | YVRQRTMRMS | RHSSGPRRNR |
300:
DTMMSLLKTV | VIVLGAFIIC | WTPGLVLLLL | DVCCPQCDVL | AYEKFFLLLA |
350:
EFNSAMNPII | YSYRDKEMSA | TFRQILCCQR | SENPTGPTEG | SDRSASSLNH |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
Bovine
ELISA Kit for Human LPA receptor 1
ELISA Kit for Human LPA receptor 1
ELISA Kit for Human LPA receptor 1
ELISA Kit for Human LPA receptor 1
CLIA Kit for Human LPA receptor 1
CLIA Kit for Human LPA receptor 1
CLIA Kit for Human LPA receptor 1
CLIA Kit for Human LPA receptor 1
Polyclonal Antibody for Human LPA receptor 1
Polyclonal Antibody for Human LPA receptor 1
Polyclonal Antibody for Human LPA receptor 1
Polyclonal Antibody for Human LPA receptor 1
Monoclonal Antibody for Human LPA receptor 1
Monoclonal Antibody for Human LPA receptor 1
Monoclonal Antibody for Human LPA receptor 1
Monoclonal Antibody for Human LPA receptor 1
Protein for Human LPA receptor 1
Protein for Human LPA receptor 1
Protein for Human LPA receptor 1
Protein for Human LPA receptor 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Brain .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue :
Thalamus .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Hippocampus .
tissue :
Testis .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : REVIEW
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH RALA AND ADRBK1