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Index > Protein center > LPPR4(Gene name) > Human
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  • LPPR4 (Gene name),
  • Lipid phosphate phosphatase-related protein type 4 (Protein name ),  LPPR4_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    LPPR4(KIAA0455;PRG1);
    Protein name:
    Lipid phosphate phosphatase-related protein type 4;
    Alternative:
    Plasticity-related gene 1 protein(PRG-1);Brain-specific phosphatidic acid phosphatase-like protein 1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Hydrolyzes lysophosphatidic acid (LPA). Facilitates axonal outgrowth during development and regenerative sprouting. In the outgrowing axons acts as an ecto-enzyme and attenuates phospholipid-induced axon collapse in neurons and facilitates outgrowth in the hippocampus.
    Subcellular Location:
    Membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    763
    Sequence:
    50:
    MQRAGSSGGR | GECDISGAGR | LGLEEAARLS | CAVHTSPGGG | RRPGQAAGMS | 
    100:
    AKERPKGKVI | KDSVTLLPCF | YFVELPILAS | SVVSLYFLEL | TDVFKPVHSG | 
    150:
    FSCYDRSLSM | PYIEPTQEAI | PFLMLLSLAF | AGPAITIMVG | EGILYCCLSK | 
    200:
    RRNGVGLEPN | INAGGCNFNS | FLRRAVRFVG | VHVFGLCSTA | LITDIIQLST | 
    250:
    GYQAPYFLTV | CKPNYTSLNV | SCKENSYIVE | DICSGSDLTV | INSGRKSFPS | 
    300:
    QHATLAAFAA | VYVSMYFNST | LTDSSKLLKP | LLVFTFIICG | IICGLTRITQ | 
    350:
    YKNHPVDVYC | GFLIGGGIAL | YLGLYAVGNF | LPSDESMFQH | RDALRSLTDL | 
    400:
    NQDPNRLLSA | KNGSSSDGIA | HTEGILNRNH | RDASSLTNLK | RANADVEIIT | 
    450:
    PRSPMGKENM | VTFSNTLPRA | NTPSVEDPVR | RNASIHASMD | SARSKQLLTQ | 
    500:
    WKNKNESRKL | SLQVIEPEPG | QSPPRSIEMR | SSSEPSRVGV | NGDHHGPGNQ | 
    550:
    YLKIQPGAVP | GCNNSMPGGP | RVSIQSRPGS | SQLVHIPEET | QENISTSPKS | 
    600:
    SSARAKWLKA | AEKTVACNRS | NSQPRIMQVI | AMSKQQGVLQ | SSPKNTEGST | 
    650:
    VSCTGSIRYK | TLTDHEPSGI | VRVEAHPENN | RPIIQIPSTE | GEGSGSWKWK | 
    700:
    APEKGSLRQT | YELNDLNRDS | ESCESLKDSF | GSGDRKRSNI | DSNEHHHHGI | 
    750:
    TTIRVTPVEG | SEIGSETLSI | SSSRDSTLRR | KGNIILIPER | SNSPENTRNI | 
    763:
    FYKGTSPTRA | YKD
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    KEGG:
    Pfam:
    UniGene:
    String:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Lipid phosphate phosphatase-related protein type 4
    Cat.:
    E5668h
    Price:
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human Lipid phosphate phosphatase-related protein type 4
    Cat.:
    E5668m
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Lipid phosphate phosphatase-related protein type 4
    Cat.:
    E5668r
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Lipid phosphate phosphatase-related protein type 4
    Cat.:
    U5668h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Lipid phosphate phosphatase-related protein type 4
    Cat.:
    U5668m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Lipid phosphate phosphatase-related protein type 4
    Cat.:
    U5668r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Lipid phosphate phosphatase-related protein type 4
    Cat.:
    P5668Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Lipid phosphate phosphatase-related protein type 4
    Polyclonal Antibody for Human Lipid phosphate phosphatase-related protein type 4
    Cat.:
    P5668Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Lipid phosphate phosphatase-related protein type 4
    Monoclonal Antibody for Human Lipid phosphate phosphatase-related protein type 4
    Monoclonal Antibody for Human Lipid phosphate phosphatase-related protein type 4
    Protein for Human Lipid phosphate phosphatase-related protein type 4
    Protein for Human Lipid phosphate phosphatase-related protein type 4
    Protein for Human Lipid phosphate phosphatase-related protein type 4

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    Linearity
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    References
    1. 1.
      "A new phospholipid phosphatase, PRG-1, is involved in axon growth and regenerative sprouting."
      Braeuer A.U. , Savaskan N.E. , Kuehn H. , Prehn S. , Ninnemann O. , Nitsch R.
      Nat. Neurosci.6:572-578(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;TISSUE SPECIFICITY;MUTAGENESIS OF HIS-252
      tissue: Brain.
    2. 2.
      "Lipid phosphate phosphatase related proteins."
      Morris A.J. , Sigal Y.J. , McDermott M. , Sciorra V.A.
      Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    3. 3.
      "Characterization of cDNA clones in size-fractionated cDNA libraries from human brain."
      Seki N. , Ohira M. , Nagase T. , Ishikawa K. , Miyajima N. , Nakajima D. , Nomura N. , Ohara O.
      DNA Res.4:345-349(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Brain.
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 15-763 (ISOFORM 1)
      tissue: Brain.
    5. 5.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "A new brain specific member of the PAP-2 family."
      Ninnemann O. , Brauer A.U. , Savaskan N. , Nitsch R.
      Submitted (2001-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 24-763 (ISOFORM 1)
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 111-763 (ISOFORM 1)
      tissue: Amygdala.
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