LRP2 ELISA Kit for Human(Homo sapiens) | EIAab.comLRP2 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > LRP2(Gene name) > Human

LRP2 (Gene name),

Low-density lipoprotein receptor-related protein 2 (Protein name ), LRP2_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

LRP2;

Protein name:

Low-density lipoprotein receptor-related protein 2(LRP-2);

Alternative:

Megalin;Glycoprotein 330(gp330);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Binds plasminogen, extracellular matrix components, plasminogen activator-plasminogen activator inhibitor type I complex, apolipoprotein E-enriched beta-VLDL, lipoprotein lipase, lactoferrin, CLU/clusterin and calcium. Forms a multimeric complex together with a receptor-associated protein (RAP). Binds to ankyrin-repeat family A protein 2 (ANKRA2). Interacts with LRP2BP.

Function:

Acts together with cubilin to mediate HDL endocytosis (By similarity). May participate in regulation of parathyroid-hormone and para-thyroid-hormone-related protein release.

Subcellular Location:

Membrane Single-pass type I membrane protein Membrane coated pit

Protein Attributes:

Sequence length:

4655

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EDSEV

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF07645

STRING:

9606.ENSP00000263816

Pfam:

PF12662

KEGG:

hsa:4036

MIM:

222448

UniGene:

Hs.657729

SMR:

P98164

String:

P98164

Uniprot:

P98164

FOR

ELISA Kit for Human LRP-2

Cat.:

E0001r

Price:

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Packing:

96T

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ELISA Kit for Human LRP-2

Cat.:

E0001m

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Packing:

96T

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ELISA Kit for Human LRP-2

Cat.:

E0001h

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Human LRP-2

Cat.:

U0001h

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Manual:

Looking for manual.

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Packing:

96T

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CLIA Kit for Human LRP-2

Cat.:

U0001m

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MSDS:

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Packing:

96T

CLIA Kit for Human LRP-2

Cat.:

U0001r

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human LRP-2

Cat.:

P0001Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human LRP-2

Cat.:

P0001Rb-r

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human LRP-2

Cat.:

P0001Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human LRP-2

Protein for Human LRP-2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Cloning and sequencing of human gp330, a Ca(2+)-binding receptor with potential intracellular signaling properties."
Hjaelm G. , Murray E. , Crumley G. , Harazim W. , Lundgren S. , Onyango I. , Ek B. , Larsson M. , Juhlin C. , Hellman P. , Davis H. , Aekerstroem G. , Rask L. , Morse B.
Eur. J. Biochem.239:132-137(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT SER-83
tissue: Kidney.
2.

"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
3.

"Chromosomal localization of human genes for the LDL receptor family member glycoprotein 330 (LRP2) and its associated protein RAP (LRPAP1)."
Korenberg J.R. , Argraves K.M. , Chen X.N. , Tran H. , Strickland D.K. , Argraves W.S.
Genomics22:88-93(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 2705-4453;VARIANTS GLU-4094 AND LEU-4210
tissue: Kidney.
4.

"A protein involved in calcium sensing of the human parathyroid and placental cytotrophoblast cells belongs to the LDL-receptor protein superfamily."
Lundgren S. , Hjaelm G. , Hellman P. , Ek B. , Juhlin C. , Rastad J. , Klareskog L. , Aakerstroem G. , Rask L.
Exp. Cell Res.212:344-350(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 4139-4406
5.

"Identification of glycoprotein 330 as an endocytic receptor for apolipoprotein J/clusterin."
Kounnas M.Z. , Loukinova E.B. , Stefansson S. , Harmony J.A.K. , Brewer B.H. , Strickland D.K. , Argraves W.S.
J. Biol. Chem.270:13070-13075(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CLU
6.

"Cytosolic adaptor protein Dab2 is an intracellular ligand of endocytic receptor gp600/megalin."
Oleinikov A.V. , Zhao J. , Makker S.P.
Biochem. J.347:613-621(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DAB2
7.

"Functional interaction of megalin with the megalin-binding protein (MegBP), a novel tetratrico peptide repeat-containing adaptor molecule."
Petersen H.H. , Hilpert J. , Militz D. , Zandler V. , Jacobsen C. , Roebroek A.J.M. , Willnow T.E.
J. Cell Sci.116:453-461(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH LRP2BP
8.

"The adaptor disabled-2 binds to the third psi xNPxY sequence on the cytoplasmic tail of megalin."
Gallagher H. , Oleinikov A.V. , Fenske C. , Newman D.J.
Biochimie86:179-182(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DAB2
9.

"The consensus coding sequences of human breast and colorectal cancers."
Sjoeblom T. , Jones S. , Wood L.D. , Parsons D.W. , Lin J. , Barber T.D. , Mandelker D. , Leary R.J. , Ptak J. , Silliman N. , Szabo S. , Buckhaults P. , Farrell C. , Meeh P. , Markowitz S.D. , Willis J. , Dawson D. , Willson J.K.V. , more...
Science314:268-274(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] VAL-4272
10.

"Mutations in LRP2, which encodes the multiligand receptor megalin, cause Donnai-Barrow and facio-oculo-acoustico-renal syndromes."
Kantarci S. , Al-Gazali L. , Hill R.S. , Donnai D. , Black G.C.M. , Bieth E. , Chassaing N. , Lacombe D. , Devriendt K. , Teebi A. , Loscertales M. , Robson C. , Liu T. , MacLaughlin D.T. , Noonan K.M. , Russell M.K. , Walsh C.A. , Donahoe P.K. , more...
Nat. Genet.39:957-959(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT DBS HIS-2522
11.

"Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma."
Varela I. , Tarpey P. , Raine K. , Huang D. , Ong C.K. , Stephens P. , Davies H. , Jones D. , Lin M.L. , Teague J. , Bignell G. , Butler A. , Cho J. , Dalgliesh G.L. , Galappaththige D. , Greenman C. , Hardy C. , Jia M. , more...
Nature469:539-542(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT ARG-103

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