Lrp2 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comLrp2 ELISA Kit for Rat(Rattus norvegicus)

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Lrp2 (Gene name),

Low-density lipoprotein receptor-related protein 2 (Protein name ), LRP2_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Lrp2;

Protein name:

Low-density lipoprotein receptor-related protein 2(LRP-2);

Alternative:

Megalin;Glycoprotein 330(gp330);

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Binds plasminogen, extracellular matrix components, plasminogen activator-plasminogen activator inhibitor type I complex, apolipoprotein E-enriched beta-VLDL, lipoprotein lipase, lactoferrin, CLU/clusterin and calcium. Forms a multimeric complex together with a receptor-associated protein (RAP). Binds to ankyrin-repeat family A protein 2 (ANKRA2). Interacts with LRP2BP.

Function:

Acts together with cubilin to mediate HDL endocytosis (By similarity). Receptor-mediated uptake of polybasic drugs such as aprotinin, aminoglycosides and polymyxin B.

Subcellular Location:

Cell membrane Single-pass type I membrane protein Membrane clathrin-coated pit Cytoplasm Expressed in clathrin-coated pits, a soluble form is possibly derived by cleavage at the cell surface.

Protein Attributes:

Sequence length:

4660

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ANLVKEDSDV |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P98158

Pfam:

PF07645

SMR:

P98158

Pfam:

PF12662

UniGene:

Rn.26430

KEGG:

rno:29216

STRING:

10116.ENSRNOP00000043580

Uniprot:

P98158

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ELISA Kit for Rat LRP-2

Cat.:

E0001r

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Packing:

96T

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ELISA Kit for Rat LRP-2

Cat.:

E0001m

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96T

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ELISA Kit for Rat LRP-2

Cat.:

E0001h

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Looking for manual.

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Packing:

96T

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CLIA Kit for Rat LRP-2

Cat.:

U0001h

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Looking for manual.

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Packing:

96T

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CLIA Kit for Rat LRP-2

Cat.:

U0001m

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MSDS:

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Packing:

96T

CLIA Kit for Rat LRP-2

Cat.:

U0001r

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MSDS:

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Packing:

96T

Polyclonal Antibody for Rat LRP-2

Cat.:

P0001Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat LRP-2

Cat.:

P0001Rb-r

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat LRP-2

Cat.:

P0001Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat LRP-2

Protein for Rat LRP-2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Complete cloning and sequencing of rat gp330/'megalin,' a distinctive member of the low density lipoprotein receptor gene family."
Saito A. , Pietromonaco S. , Loo A.K.C. , Farquhar M.G.
Proc. Natl. Acad. Sci. U.S.A.91:9725-9729(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: Sprague-Dawley.
tissue: Kidney.
2.

"Evidence that epithelial glycoprotein 330/megalin mediates uptake of polybasic drugs."
Moestrup S.K. , Cui S. , Vorum H. , Bregengaard C. , Bjorn S.E. , Norris K. , Gliemann J. , Christensen E.I.
J. Clin. Invest.96:1404-1413(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN UPTAKE OF POLYBASIC DRUGS
3.

"Organ distribution in rats of two members of the low-density lipoprotein receptor gene family, gp330 and LRP/alpa 2MR, and the receptor-associated protein (RAP)."
Zheng G. , Bachinsky D.R. , Stamenkovic I. , Strickland D.K. , Brown D. , Andres G. , McCluskey R.T.
J. Histochem. Cytochem.42:531-542(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
4.

"Solution structure of the twelfth cysteine-rich ligand-binding repeat in rat megalin."
Wolf C.A. , Dancea F. , Shi M. , Bade-Noskova V. , Ruterjans H. , Kerjaschki D. , Lucke C.
J. Biomol. NMR37:321-328(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 1185-1229;CALCIUM-BINDING SITE;DISULFIDE BONDS

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