ALOX15B ELISA Kit for Human(Homo sapiens) | EIAab.comALOX15B ELISA Kit for Human(Homo sapiens)

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ALOX15B (Gene name),

Arachidonate 15-lipoxygenase B (Protein name ), LX15B_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

ALOX15B;

Protein name:

Arachidonate 15-lipoxygenase B(15-LOX-B);

Alternative:

Arachidonate 15-lipoxygenase type II;15-lipoxygenase 2(15-LOX-2);1.13.11.-;Linoleate 13-lipoxygenase 15-LOb);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while linoleic acid is less well metabolized.

Subcellular Location:

Cytoplasm

Protein Attributes:

Sequence length:

676

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

676:

IQERNQGLVL | PYTYLDPPLI | ENSVSI

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

hsa:247

String:

O15296

Pfam:

PF00305

UniGene:

Hs.111256

SMR:

O15296

STRING:

9606.ENSP00000369530

MIM:

603697

Uniprot:

O15296

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ELISA Kit for Human 15-LOX-B

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E1356h

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96T

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ELISA Kit for Human 15-LOX-B

Cat.:

E1356r

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96T

ELISA Kit for Human 15-LOX-B

Cat.:

E1356m

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96T

CLIA Kit for Human 15-LOX-B

Cat.:

U1356r

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96T

CLIA Kit for Human 15-LOX-B

Cat.:

U1356m

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96T

CLIA Kit for Human 15-LOX-B

Cat.:

U1356h

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96T

Polyclonal Antibody for Human 15-LOX-B

Cat.:

P1356Rb-m

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40ug/0.2ml

Polyclonal Antibody for Human 15-LOX-B

Cat.:

P1356Rb-h

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40ug/0.2ml

Polyclonal Antibody for Human 15-LOX-B

Cat.:

P1356Rb-r

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40ug/0.2ml

Monoclonal Antibody for Human 15-LOX-B

Protein for Human 15-LOX-B

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Discovery of a second 15S-lipoxygenase in humans."
Brash A.R. , Boeglin W.E. , Chang M.S.
Proc. Natl. Acad. Sci. U.S.A.94:6148-6152(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM A);VARIANT ARG-656;CATALYTIC ACTIVITY;TISSUE SPECIFICITY
tissue: Skin.
2.

"A gene cluster encoding human epidermis-type lipoxygenases at chromosome 17p13.1: cloning, physical mapping, and expression."
Krieg P. , Marks F. , Fuerstenberger G.
Genomics73:323-330(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT ARG-656;TISSUE SPECIFICITY
3.

"Evidence that arachidonate 15-lipoxygenase 2 is a negative cell cycle regulator in normal prostate epithelial cells."
Tang S. , Bhatia B. , Maldonado C.J. , Yang P. , Newman R.A. , Liu J. , Chandra D. , Traag J. , Klein R.D. , Fischer S.M. , Chopra D. , Shen J. , Zhau H.E. , Chung L.W.K. , Tang D.G.
J. Biol. Chem.277:16189-16201(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS A; B; C AND D);VARIANTS HIS-486 AND ARG-656;FUNCTION IN CELL CYCLE PROGRESSION
4.

"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
Zody M.C. , Garber M. , Adams D.J. , Sharpe T. , Harrow J. , Lupski J.R. , Nicholson C. , Searle S.M. , Wilming L. , Young S.K. , Abouelleil A. , Allen N.R. , Bi W. , Bloom T. , Borowsky M.L. , Bugalter B.E. , Butler J. , Chang J.L. , more...
Nature440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM A);VARIANT ARG-656
tissue: Skin.
7.

"Differential characteristics of human 15-lipoxygenase isozymes and a novel splice variant of 15S-lipoxygenase."
Kilty I. , Logan A. , Vickers P.J.
Eur. J. Biochem.266:83-93(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 337-484;ALTERNATIVE SPLICING (ISOFORMS A AND D);CATALYTIC ACTIVITY;BIOPHYSICOCHEMICAL PROPERTIES;KINETIC PARAMETERS;PATHWAY;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
8.

"Identification of amino acid determinants of the positional specificity of mouse 8S-lipoxygenase and human 15S-lipoxygenase-2."
Jisaka M. , Kim R.B. , Boeglin W.E. , Brash A.R.
J. Biol. Chem.275:1287-1293(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS A 15S-LIPOXYGENASE;CATALYTIC ACTIVITY;MUTAGENESIS OF ASP-602 AND VAL-603
9.

"Subcellular localization and tumor-suppressive functions of 15-lipoxygenase 2 (15-LOX2) and its splice variants."
Bhatia B. , Maldonado C.J. , Tang S. , Chandra D. , Klein R.D. , Chopra D. , Shappell S.B. , Yang P. , Newman R.A. , Tang D.G.
J. Biol. Chem.278:25091-25100(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN CELL PROLIFERATION;SUBCELLULAR LOCATION
10.

"Double dioxygenation by mouse 8S-lipoxygenase: specific formation of a potent peroxisome proliferator-activated receptor alpha agonist."
Jisaka M. , Iwanaga C. , Takahashi N. , Goto T. , Kawada T. , Yamamoto T. , Ikeda I. , Nishimura K. , Nagaya T. , Fushiki T. , Yokota K.
Biochem. Biophys. Res. Commun.338:136-143(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
11.

"15-Lipoxygenase-2 expression in human macrophages induces chemokine secretion and T cell migration."
Danielsson K.N. , Rydberg E.K. , Ingelsten M. , Akyuerek L.M. , Jirholt P. , Ullstroem C. , Forsberg G.B. , Boren J. , Wiklund O. , Hulten L.M.
Atherosclerosis199:34-40(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN CYTOKINE SECRETION
12.

"Reciprocal regulation of 12- and 15-lipoxygenases by UV-irradiation in human keratinocytes."
Yoo H. , Jeon B. , Jeon M.S. , Lee H. , Kim T.Y.
FEBS Lett.582:3249-3253(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION BY UV
13.

"Arachidonate 15-lipoxygenase type B knockdown leads to reduced lipid accumulation and inflammation in atherosclerosis."
Magnusson L.U. , Lundqvist A. , Karlsson M.N. , Skalen K. , Levin M. , Wiklund O. , Boren J. , Hulten L.M.
PLoS ONE7:E43142-E43142(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
14.

"The structure of human 15-lipoxygenase-2 with a substrate mimic."
Kobe M.J. , Neau D.B. , Mitchell C.E. , Bartlett S.G. , Newcomer M.E.
J. Biol. Chem.289:8562-8569(2014) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.63 ANGSTROMS) IN COMPLEX WITH CALCIUM AND IRON;CATALYTIC ACTIVITY;COFACTOR;FUNCTION;SUBCELLULAR LOCATION;MUTAGENESIS OF ASP-39; GLU-44 AND ASP-85

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