Gene name:
Sell (Lnhr;Ly-22) ;
Protein name:
L-selectin ;
Alternative:
Leukocyte adhesion molecule 1 (LAM-1) ;CD62 antigen-like family member L ;Lymph node homing receptor ;Leukocyte-endothelial cell adhesion molecule 1 (LECAM1) ;Lymphocyte surface MEL-14 antigen ;Lymphocyte antigen 22 (Ly-22) ;
CD:
CD62L ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Interaction with PSGL1/SELPLG and PODXL2 is required for promoting recruitment and rolling of leukocytes. This interaction is dependent on the sialyl Lewis X glycan modification of PSGL1 and PODXL2, and tyrosine sulfation modifications of PSGL1. Sulfation on Y-51 of PSGL1 is important for L-selectin binding.
Function:
Cell surface adhesion protein. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MVFPWRCQSA | QRGSWSFLKL | WIRTLLCCDL | LPHHGTHCWT | YHYSERSMNW |
100:
ENARKFCKHN | YTDLVAIQNK | REIEYLEKTL | PKNPTYYWIG | IRKIGKTWTW |
150:
VGTNKTLTKE | AENWGTGEPN | NKKSKEDCVE | IYIKRERDSG | KWNDDACHKR |
200:
KAALCYTASC | QPESCNRHGE | CVETINNNTC | ICDPGYYGPQ | CQYVIQCEPL |
250:
KAPELGTMNC | IHPLGDFSFQ | SQCAFNCSEG | SELLGNAKTE | CGASGNWTYL |
300:
EPICQVIQCM | PLAAPDLGTM | ECSHPLANFS | FTSACTFTCS | EETDLIGERK |
350:
TVCRSSGSWS | SPSPICQKTK | RSFSKIKEGD | YNPLFIPVAV | MVTAFSGLAF |
372:
IIWLARRLKK | GKKSQERMDD | PY
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Bovine
Mouse
ELISA Kit for Rat L-selectin
ELISA Kit for Rat L-selectin
ELISA Kit for Rat L-selectin
ELISA Kit for Rat L-selectin
CLIA Kit for Rat L-selectin
CLIA Kit for Rat L-selectin
CLIA Kit for Rat L-selectin
CLIA Kit for Rat L-selectin
Polyclonal Antibody for Rat L-selectin
Polyclonal Antibody for Rat L-selectin
Polyclonal Antibody for Rat L-selectin
Polyclonal Antibody for Rat L-selectin
Monoclonal Antibody for Rat L-selectin
Monoclonal Antibody for Rat L-selectin
Monoclonal Antibody for Rat L-selectin
Monoclonal Antibody for Rat L-selectin
Protein for Rat L-selectin
Protein for Rat L-selectin
Protein for Rat L-selectin
Protein for Rat L-selectin
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [MRNA];INDUCTION;TISSUE SPECIFICITY