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Index > Protein center > Selp(Gene name) > Mouse
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  • Selp (Gene name),
  • P-selectin (Protein name ),  LYAM3_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Selp(Grmp);
    Protein name:
    P-selectin;
    Alternative:
    Granule membrane protein 140(GMP-140);CD62 antigen-like family member P;Platelet activation dependent granule-external membrane protein(PADGEM);Leukocyte-endothelial cell adhesion molecule 3(LECAM3);
    CD:
    CD62P;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with SNX17. Interacts with PSGL1/SEPL and PODXL2 and mediates neutrophil adhesion and leukocyte rolling. This interaction requires the sialyl-Lewis X epitope of PSGL1 and PODXL2, and specific tyrosine sulfation on PSGL1.
    Function:
    Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with PSGL1.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    768
    Sequence:
    50:
    MAGCPKGSWT | PRLRSVILGG | AQLIWFSALI | SELVNQKEVA | AWTYNYSTKA | 
    100:
    YSWNNSRVFC | RRHFTDLVAI | QNKNEIAHLN | DVIPFFNSYY | WIGIRKINNK | 
    150:
    WTWVGTNKTL | TEEAENWADN | EPNNKKNNQD | CVEIYIKSNS | APGKWNDEPC | 
    200:
    FKRKRALCYT | ASCQDMSCSN | QGECIETIGS | YTCSCYPGFY | GPECEYVKEC | 
    250:
    GKVNIPQHVL | MNCSHPLGEF | SFNSQCTFSC | AEGYELDGPG | ELQCLASGIW | 
    300:
    TNNPPKCDAV | QCQSLEAPPH | GTMACMHPIA | AFAYDSSCKF | ECQPGYRARG | 
    350:
    SNTLHCTGSG | QWSEPLPTCE | AIACEPPEIP | IHGSMDCVPS | TGTFGYNSSC | 
    400:
    TFLCAEGFVL | KGNDAIQCAD | SGQWTAPAPF | CEALQCPEFP | VPSKAQVNCS | 
    450:
    DPFGTLTYQS | VCSFSCDEGS | LLVGASVIRC | LATGHWNGAP | PECQAVSCAP | 
    500:
    MLSPENGSMT | CVQPLGNSTY | KSTCQFMCDE | GFYLSGPERL | DCSPSGHWTG | 
    550:
    TPPTCEAIKC | PGIFAPEQGN | LDCSHVHGEF | GVGSICHFSC | NEDFELLGSE | 
    600:
    NVECTVSGRW | SAPPPTCKGI | TSLPAPAVRC | PALTTPGQGT | MSCQHHLGSF | 
    650:
    GPNTTCYFGC | KTGFTLRGAN | SLRCRASGQW | TAVTPMCRAV | KCSELHMDTA | 
    700:
    VAMNCSNPWG | NFSYGSTCTF | QCPEGQSLNG | SVRATCREDG | HWSDAMPTCQ | 
    750:
    AGTLTIQEAL | TYLGGAVAST | TGLAVGGTLL | ALLRKRLRKK | DDGKCPLNPH | 
    768:
    SHLGTYGVFT | NAAYDPTP
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    Pfam:
    String:
    UniGene:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse P-selectin
    Cat.:
    E0115h
    Price:
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Mouse P-selectin
    Cat.:
    E0115m
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
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    Please sign in first.
    ELISA Kit for Mouse P-selectin
    Cat.:
    E0115r
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse P-selectin
    Cat.:
    E0115b
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse P-selectin
    Cat.:
    U0115m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse P-selectin
    Cat.:
    U0115h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse P-selectin
    Cat.:
    U0115r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse P-selectin
    Cat.:
    U0115b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse P-selectin
    Cat.:
    P0115Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse P-selectin
    Cat.:
    P0115Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse P-selectin
    Cat.:
    P0115Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse P-selectin
    Monoclonal Antibody for Mouse P-selectin
    Monoclonal Antibody for Mouse P-selectin
    Monoclonal Antibody for Mouse P-selectin
    Monoclonal Antibody for Mouse P-selectin
    Protein for Mouse P-selectin
    Protein for Mouse P-selectin
    Protein for Mouse P-selectin
    Protein for Mouse P-selectin

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    Linearity
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    References
    1. 1.
      "Cloning of the mouse endothelial selectins. Expression of both E- and P-selectin is inducible by tumor necrosis factor alpha."
      Weller A. , Isenmann S. , Vestweber D.
      J. Biol. Chem.267:15176-15183(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];INDUCTION
    2. 2.
      "Molecular cloning and analysis of in vivo expression of murine P-selectin."
      Sanders W.E. Jr. , Wilson R.W. , Ballantyne C.M. , Beaudet A.L.
      Blood80:795-800(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];INDUCTION
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    4. 4.
      "P-, E-, and L-selectin mediate migration of activated CD8+ T lymphocytes into inflamed skin."
      Hirata T. , Furie B.C. , Furie B.
      J. Immunol.169:4307-4313(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    5. 5.
      "N-terminal residues in murine P-selectin glycoprotein ligand-1 required for binding to murine P-selectin."
      Xia L. , Ramachandran V. , McDaniel J.M. , Nguyen K.N. , Cummings R.D. , McEver R.P.
      Blood101:552-559(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SELPLG
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