Protein name:
P-selectin ;
Alternative:
Granule membrane protein 140 (GMP-140) ;CD62 antigen-like family member P ;Platelet activation dependent granule-external membrane protein (PADGEM) ;Leukocyte-endothelial cell adhesion molecule 3 (LECAM3) ;
CD:
CD62P ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with SNX17. Interacts with PSGL1/SEPL and PODXL2 and mediates neutrophil adhesion and leukocyte rolling. This interaction requires the sialyl-Lewis X epitope of PSGL1 and PODXL2, and specific tyrosine sulfation on PSGL1.
Function:
Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with PSGL1.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MAGCPKGSWT | PRLRSVILGG | AQLIWFSALI | SELVNQKEVA | AWTYNYSTKA |
100:
YSWNNSRVFC | RRHFTDLVAI | QNKNEIAHLN | DVIPFFNSYY | WIGIRKINNK |
150:
WTWVGTNKTL | TEEAENWADN | EPNNKKNNQD | CVEIYIKSNS | APGKWNDEPC |
200:
FKRKRALCYT | ASCQDMSCSN | QGECIETIGS | YTCSCYPGFY | GPECEYVKEC |
250:
GKVNIPQHVL | MNCSHPLGEF | SFNSQCTFSC | AEGYELDGPG | ELQCLASGIW |
300:
TNNPPKCDAV | QCQSLEAPPH | GTMACMHPIA | AFAYDSSCKF | ECQPGYRARG |
350:
SNTLHCTGSG | QWSEPLPTCE | AIACEPPEIP | IHGSMDCVPS | TGTFGYNSSC |
400:
TFLCAEGFVL | KGNDAIQCAD | SGQWTAPAPF | CEALQCPEFP | VPSKAQVNCS |
450:
DPFGTLTYQS | VCSFSCDEGS | LLVGASVIRC | LATGHWNGAP | PECQAVSCAP |
500:
MLSPENGSMT | CVQPLGNSTY | KSTCQFMCDE | GFYLSGPERL | DCSPSGHWTG |
550:
TPPTCEAIKC | PGIFAPEQGN | LDCSHVHGEF | GVGSICHFSC | NEDFELLGSE |
600:
NVECTVSGRW | SAPPPTCKGI | TSLPAPAVRC | PALTTPGQGT | MSCQHHLGSF |
650:
GPNTTCYFGC | KTGFTLRGAN | SLRCRASGQW | TAVTPMCRAV | KCSELHMDTA |
700:
VAMNCSNPWG | NFSYGSTCTF | QCPEGQSLNG | SVRATCREDG | HWSDAMPTCQ |
750:
AGTLTIQEAL | TYLGGAVAST | TGLAVGGTLL | ALLRKRLRKK | DDGKCPLNPH |
768:
SHLGTYGVFT | NAAYDPTP
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
Bovine
ELISA Kit for Mouse P-selectin
ELISA Kit for Mouse P-selectin
ELISA Kit for Mouse P-selectin
ELISA Kit for Mouse P-selectin
CLIA Kit for Mouse P-selectin
CLIA Kit for Mouse P-selectin
CLIA Kit for Mouse P-selectin
CLIA Kit for Mouse P-selectin
Polyclonal Antibody for Mouse P-selectin
Polyclonal Antibody for Mouse P-selectin
Polyclonal Antibody for Mouse P-selectin
Polyclonal Antibody for Mouse P-selectin
Monoclonal Antibody for Mouse P-selectin
Monoclonal Antibody for Mouse P-selectin
Monoclonal Antibody for Mouse P-selectin
Monoclonal Antibody for Mouse P-selectin
Protein for Mouse P-selectin
Protein for Mouse P-selectin
Protein for Mouse P-selectin
Protein for Mouse P-selectin
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];INDUCTION
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];INDUCTION
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH SELPLG