Gene name:
LPCAT3 (MBOAT5;OACT5) ;
Protein name:
Lysophospholipid acyltransferase 5 (LPLAT 5) ;
Alternative:
2.3.1.n6;1-acylglycerophosphoserine O-acyltransferase ) ;2.3.1.23;1-acylglycerophosphocholine O-acyltransferase ) ;Lysophosphatidylcholine acyltransferase 3 (Lyso-PC acyltransferase 3) ;Lysophosphatidylcholine acyltransferase (LPCAT;Lyso-PC acyltransferase) ;Membrane-bound O-acyltransferase domain-containing protein 5 (O-acyltransferase domain-containing protein 5) ;Lysophosphatidylserine acyltransferase (LPSAT;Lyso-PS acyltransferase) ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Acyltransferase which mediates the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC) (LPCAT activity). Catalyzes also the conversion of lysophosphatidylserine (1-acyl-2-hydroxy-sn-glycero-3-phospho-L-serine or LPS) into phosphatidylserine (1,2-diacyl-sn-glycero-3-phospho-L-serine or PS) (LPSAT activity). Has also weak lysophosphatidylethanolamine acyltransferase activity (LPEAT activity). Favors polyunsaturated fatty acyl-CoAs as acyl donors compared to saturated fatty acyl-CoAs. Seems to be the major enzyme contributing to LPCAT activity in the liver. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle.
Subcellular Location:
Endoplasmic reticulum membrane
Multi-pass membrane protein
Protein Attributes:
50:
MASSAEGDEG | TVVALAGVLQ | SGFQELSLNK | LATSLGASEQ | ALRLIISIFL |
100:
GYPFALFYRH | YLFYKETYLI | HLFHTFTGLS | IAYFNFGNQL | YHSLLCIVLQ |
150:
FLILRLMGRT | ITAVLTTFCF | QMAYLLAGYY | YTATGNYDIK | WTMPHCVLTL |
200:
KLIGLAVDYF | DGGKDQNSLS | SEQQKYAIRG | VPSLLEVAGF | SYFYGAFLVG |
250:
PQFSMNHYMK | LVQGELIDIP | GKIPNSIIPA | LKRLSLGLFY | LVGYTLLSPH |
300:
ITEDYLLTED | YDNHPFWFRC | MYMLIWGKFV | LYKYVTCWLV | TEGVCILTGL |
350:
GFNGFEEKGK | AKWDACANMK | VWLFETNPRF | TGTIASFNIN | TNAWVARYIF |
400:
KRLKFLGNKE | LSQGLSLLFL | ALWHGLHSGY | LVCFQMEFLI | VIVERQAARL |
450:
IQESPTLSKL | AAITVLQPFY | YLVQQTIHWL | FMGYSMTAFC | LFTWDKWLKV |
487:
YKSIYFLGHI | FFLSLLFILP | YIHKAMVPRK | EKLKKME
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Human
Bovine
Mouse
ELISA Kit for Human LPLAT 5
ELISA Kit for Human LPLAT 5
ELISA Kit for Human LPLAT 5
ELISA Kit for Human LPLAT 5
CLIA Kit for Human LPLAT 5
CLIA Kit for Human LPLAT 5
CLIA Kit for Human LPLAT 5
CLIA Kit for Human LPLAT 5
Polyclonal Antibody for Human LPLAT 5
Polyclonal Antibody for Human LPLAT 5
Polyclonal Antibody for Human LPLAT 5
Polyclonal Antibody for Human LPLAT 5
Monoclonal Antibody for Human LPLAT 5
Monoclonal Antibody for Human LPLAT 5
Monoclonal Antibody for Human LPLAT 5
Monoclonal Antibody for Human LPLAT 5
Protein for Human LPLAT 5
Protein for Human LPLAT 5
Protein for Human LPLAT 5
Protein for Human LPLAT 5
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
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[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Colon .
tissue :
Pancreas .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] OF 50-487 (ISOFORM 1)
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Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 107-487 (ISOFORM 1/2)
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION;FUNCTION;SUBCELLULAR LOCATION;BIOPHYSICOCHEMICAL PROPERTIES;TISSUE SPECIFICITY
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;TISSUE SPECIFICITY;SUBSTRATE SPECIFICITY