MED31 ELISA Kit for Human(Homo sapiens) | EIAab.comMED31 ELISA Kit for Human(Homo sapiens)

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MED31 (Gene name),

Mediator of RNA polymerase II transcription subunit 31 (Protein name ), MED31_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

MED31(CGI-125;SOH1);

Protein name:

Mediator of RNA polymerase II transcription subunit 31;

Alternative:

Mediator complex subunit SOH1(hSOH1);Mediator complex subunit 31;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.

Function:

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

131

Sequence:

50:

100:

131:

QILHWQHYSR | KRMRLQQALA | EQQQQNNTSG | K

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q9Y3C7

STRING:

9606.ENSP00000225728

SMR:

Q9Y3C7

KEGG:

hsa:51003

Pfam:

PF05669

UniGene:

Hs.567493

Uniprot:

Q9Y3C7

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ELISA Kit for Human Mediator of RNA polymerase II transcription subunit 31

Cat.:

E11531h

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Manual:

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Packing:

96T

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ELISA Kit for Human Mediator of RNA polymerase II transcription subunit 31

MSDS:

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ELISA Kit for Human Mediator of RNA polymerase II transcription subunit 31

Cat.:

E11531m

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MSDS:

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Packing:

96T

CLIA Kit for Human Mediator of RNA polymerase II transcription subunit 31

Cat.:

U11531m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Mediator of RNA polymerase II transcription subunit 31

MSDS:

Please sign in first.

CLIA Kit for Human Mediator of RNA polymerase II transcription subunit 31

Cat.:

U11531h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

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Polyclonal Antibody for Human Mediator of RNA polymerase II transcription subunit 31

Cat.:

P11531Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Mediator of RNA polymerase II transcription subunit 31

Monoclonal Antibody for Human Mediator of RNA polymerase II transcription subunit 31

Protein for Human Mediator of RNA polymerase II transcription subunit 31

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics."
Lai C.-H. , Chou C.-Y. , Ch'ang L.-Y. , Liu C.-S. , Lin W.-C.
Genome Res.10:703-713(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
2.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
3.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Prostate.
5.

"A novel human SRB/MED-containing cofactor complex, SMCC, involved in transcription regulation."
Gu W. , Malik S. , Ito M. , Yuan C.-X. , Fondell J.D. , Zhang X. , Martinez E. , Qin J. , Roeder R.G.
Mol. Cell3:97-108(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY;IDENTIFICATION IN THE SMCC COMPLEX
6.

Gu W. , Malik S. , Ito M. , Yuan C.-X. , Fondell J.D. , Zhang X. , Martinez E. , Qin J. , Roeder R.G.
Mol. Cell3:541-541(1999)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
7.

"The TRAP/Mediator coactivator complex interacts directly with estrogen receptors alpha and beta through the TRAP220 subunit and directly enhances estrogen receptor function in vitro."
Kang Y.K. , Guermah M. , Yuan C.-X. , Roeder R.G.
Proc. Natl. Acad. Sci. U.S.A.99:2642-2647(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY;IDENTIFICATION IN THE MEDIATOR COMPLEX;INTERACTION OF THE MEDIATOR COMPLEX WITH ESR1 AND ESR2
8.

"Identification of mammalian Mediator subunits with similarities to yeast Mediator subunits Srb5, Srb6, Med11, and Rox3."
Sato S. , Tomomori-Sato C. , Banks C.A.S. , Sorokina I. , Parmely T.J. , Kong S.E. , Jin J. , Cai Y. , Lane W.S. , Brower C.S. , Conaway R.C. , Conaway J.W.
J. Biol. Chem.278:15123-15127(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MED19
9.

"A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology."
Sato S. , Tomomori-Sato C. , Parmely T.J. , Florens L. , Zybailov B. , Swanson S.K. , Banks C.A.S. , Jin J. , Cai Y. , Washburn M.P. , Conaway J.W. , Conaway R.C.
Mol. Cell14:685-691(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY;IDENTIFICATION IN THE MEDIATOR COMPLEX
10.

"MED1/TRAP220 exists predominantly in a TRAP/Mediator subpopulation enriched in RNA polymerase II and is required for ER-mediated transcription."
Zhang X. , Krutchinsky A. , Fukuda A. , Chen W. , Yamamura S. , Chait B.T. , Roeder R.G.
Mol. Cell19:89-100(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY;IDENTIFICATION IN THE MEDIATOR COMPLEX;ASSOCIATION OF THE MEDIATOR COMPLEX WITH RNA POLYMERASE II
11.

"Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
Daub H. , Olsen J.V. , Bairlein M. , Gnad F. , Oppermann F.S. , Korner R. , Greff Z. , Keri G. , Stemmann O. , Mann M.
Mol. Cell31:438-448(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
12.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
13.

"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Van Damme P. , Lasa M. , Polevoda B. , Gazquez C. , Elosegui-Artola A. , Kim D.S. , De Juan-Pardo E. , Demeyer K. , Hole K. , Larrea E. , Timmerman E. , Prieto J. , Arnesen T. , Sherman F. , Gevaert K. , Aldabe R.
Proc. Natl. Acad. Sci. U.S.A.109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]

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