MERTK ELISA Kit for Human(Homo sapiens) | EIAab.comMERTK ELISA Kit for Human(Homo sapiens)

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Index > Protein center > MERTK(Gene name) > Human

MERTK (Gene name),

Tyrosine-protein kinase Mer (Protein name ), MERTK_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

MERTK(MER);

Protein name:

Tyrosine-protein kinase Mer;

Alternative:

Receptor tyrosine kinase MerTK;Proto-oncogene c-Mer;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts (upon activation) with TNK2; stimulates TNK2 autophosphorylation.

Function:

In case of filovirus infection, seems to function as a cell entry factor.

Subcellular Location:

Membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

999

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

900:

950:

999:

AEKNSVLPGE | RLVRNGVSWS | HSSMLPLGSS | LPDELLFADD | SSEGSEVLM

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q12866

MIM:

604705

SMR:

Q12866

STRING:

9606.ENSP00000295408

KEGG:

hsa:10461

Pfam:

PF00041

UniGene:

Hs.306178

Uniprot:

Q12866

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ELISA Kit for Human Tyrosine-protein kinase Mer

Cat.:

E1419h

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96T

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ELISA Kit for Human Tyrosine-protein kinase Mer

Cat.:

E1419r

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96T

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ELISA Kit for Human Tyrosine-protein kinase Mer

Cat.:

E1419m

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Packing:

96T

CLIA Kit for Human Tyrosine-protein kinase Mer

Cat.:

U1419r

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96T

CLIA Kit for Human Tyrosine-protein kinase Mer

Cat.:

U1419h

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96T

CLIA Kit for Human Tyrosine-protein kinase Mer

Cat.:

U1419m

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96T

Polyclonal Antibody for Human Tyrosine-protein kinase Mer

Cat.:

P1419Rb-m

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40ug/0.2ml

Polyclonal Antibody for Human Tyrosine-protein kinase Mer

Cat.:

P1419Rb-h

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40ug/0.2ml

Polyclonal Antibody for Human Tyrosine-protein kinase Mer

Cat.:

P1419Rb-r

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40ug/0.2ml

Monoclonal Antibody for Human Tyrosine-protein kinase Mer

Protein for Human Tyrosine-protein kinase Mer

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Cloning and mRNA expression analysis of a novel human protooncogene, c-mer."
Graham D.K. , Dawson T.L. , Mullaney D.L. , Snodgrass H.R. , Earp H.S.
Cell Growth Differ.5:647-657(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT ASN-118
tissue: Peripheral blood leukocyte.
2.

Graham D.K. , Dawson T.L. , Mullaney D.L. , Snodgrass H.R. , Earp H.S.
Cell Growth Differ.5:1022-1022(1994)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
3.

"Mutations in MERTK, the human orthologue of the RCS rat retinal dystrophy gene, cause retinitis pigmentosa."
Gal A. , Li Y. , Thompson D.A. , Weir J. , Orth U. , Jacobson S.G. , Apfelstedt-Sylla E. , Vollrath D.
Nat. Genet.26:270-271(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 22-999;VARIANTS RP38 LYS-540; CYS-661 AND THR-871;VARIANTS SER-20; ASN-118; THR-282; HIS-293; LYS-466; SER-498; VAL-518 AND VAL-871
4.

"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"Identification of the major autophosphorylation sites of Nyk/Mer, an NCAM-related receptor tyrosine kinase."
Ling L. , Templeton D. , Kung H.J.
J. Biol. Chem.271:18355-18362(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT TYR-749; TYR-753 AND TYR-754
6.

"Identification of Gas6 as a ligand for Mer, a neural cell adhesion molecule related receptor tyrosine kinase implicated in cellular transformation."
Chen J. , Carey K. , Godowski P.J.
Oncogene14:2033-2039(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH GAS6
7.

"An SH2 domain-dependent, phosphotyrosine-independent interaction between Vav1 and the Mer receptor tyrosine kinase: a mechanism for localizing guanine nucleotide-exchange factor action."
Mahajan N.P. , Earp H.S.
J. Biol. Chem.278:42596-42603(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH VAV1
8.

"Activated tyrosine kinase Ack1 promotes prostate tumorigenesis: role of Ack1 in polyubiquitination of tumor suppressor Wwox."
Mahajan N.P. , Whang Y.E. , Mohler J.L. , Earp H.S.
Cancer Res.65:10514-10523(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TNK2
9.

"Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
Liu T. , Qian W.-J. , Gritsenko M.A. , Camp D.G. II , Monroe M.E. , Moore R.J. , Smith R.D.
J. Proteome Res.4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-442
tissue: Plasma.
10.

"Signalling and functional diversity within the Axl subfamily of receptor tyrosine kinases."
Hafizi S. , Dahlback B.
Cytokine Growth Factor Rev.17:295-304(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON FUNCTION
11.

"Tyro3 family-mediated cell entry of Ebola and Marburg viruses."
Shimojima M. , Takada A. , Ebihara H. , Neumann G. , Fujioka K. , Irimura T. , Jones S. , Feldmann H. , Kawaoka Y.
J. Virol.80:10109-10116(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS CELL ENTRY FACTOR IN FILOVIRUS INFECTION
12.

"Immunobiology of the TAM receptors."
Lemke G. , Rothlin C.V.
Nat. Rev. Immunol.8:327-336(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON FUNCTION
13.

"Large-scale proteomics analysis of the human kinome."
Oppermann F.S. , Gnad F. , Olsen J.V. , Hornberger R. , Greff Z. , Keri G. , Mann M. , Daub H.
Mol. Cell. Proteomics8:1751-1764(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-543 AND SER-935;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
14.

"Galectin-3 is a new MerTK-specific eat-me signal."
Caberoy N.B. , Alvarado G. , Bigcas J.L. , Li W.
J. Cell. Physiol.227:401-407(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH LGALS3
15.

"Solution structures of the FN3 domain of human proto-oncogene tyrosine-protein kinase MER precursor."
RIKEN structural genomics initiative (RSGI)
Submitted (2006-12) to the PDB data bank

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 366-483
16.

"Patterns of somatic mutation in human cancer genomes."
Greenman C. , Stephens P. , Smith R. , Dalgliesh G.L. , Hunter C. , Bignell G. , Davies H. , Teague J. , Butler A. , Stevens C. , Edkins S. , O'Meara S. , Vastrik I. , Schmidt E.E. , Avis T. , Barthorpe S. , Bhamra G. , Buck G. , more...
Nature446:153-158(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS [LARGE SCALE ANALYSIS] SER-20; ASN-118; MET-185; THR-282; LYS-289; HIS-293; GLY-446; LEU-452; LYS-466; SER-498; VAL-518; GLU-662; SER-708; GLN-823; TRP-865 AND ILE-870
17.

"Detection of variants in 15 genes in 87 unrelated Chinese patients with Leber congenital amaurosis."
Li L. , Xiao X. , Li S. , Jia X. , Wang P. , Guo X. , Jiao X. , Zhang Q. , Hejtmancik J.F.
PLoS ONE6:E19458-E19458(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS VAL-214 AND LEU-958

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