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Index > Protein center > MAT2A(Gene name) > Human
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  • MAT2A (Gene name),
  • S-adenosylmethionine synthase isoform type-2 (Protein name ),  METK2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    MAT2A(AMS2;MATA2);
    Protein name:
    S-adenosylmethionine synthase isoform type-2(AdoMet synthase 2);
    Alternative:
    Methionine adenosyltransferase II(MAT-II);Methionine adenosyltransferase 2(MAT 2);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Heterotetramer composed of 2 catalytic alpha subunits (alpha and alpha') (MAT2A) and 1 copy of beta subunit (MAT2B).
    Function:
    Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    395
    Sequence:
    50:
    MNGQLNGFHE | AFIEEGTFLF | TSESVGEGHP | DKICDQISDA | VLDAHLQQDP | 
    100:
    DAKVACETVA | KTGMILLAGE | ITSRAAVDYQ | KVVREAVKHI | GYDDSSKGFD | 
    150:
    YKTCNVLVAL | EQQSPDIAQG | VHLDRNEEDI | GAGDQGLMFG | YATDETEECM | 
    200:
    PLTIVLAHKL | NAKLAELRRN | GTLPWLRPDS | KTQVTVQYMQ | DRGAVLPIRV | 
    250:
    HTIVISVQHD | EEVCLDEMRD | ALKEKVIKAV | VPAKYLDEDT | IYHLQPSGRF | 
    300:
    VIGGPQGDAG | LTGRKIIVDT | YGGWGAHGGG | AFSGKDYTKV | DRSAAYAARW | 
    350:
    VAKSLVKGGL | CRRVLVQVSY | AIGVSHPLSI | SIFHYGTSQK | SERELLEIVK | 
    395:
    KNFDLRPGVI | VRDLDLKKPI | YQRTAAYGHF | GRDSFPWEVP | KKLKY
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    UniGene:
    KEGG:
    String:
    MIM:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human AdoMet synthase 2
    Cat.:
    E12626h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human AdoMet synthase 2
    Cat.:
    E12626m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human AdoMet synthase 2
    Cat.:
    E12626r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human AdoMet synthase 2
    Cat.:
    U12626m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human AdoMet synthase 2
    Cat.:
    U12626h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human AdoMet synthase 2
    Cat.:
    U12626r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human AdoMet synthase 2
    Polyclonal Antibody for Human AdoMet synthase 2
    Polyclonal Antibody for Human AdoMet synthase 2
    Cat.:
    P12626Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human AdoMet synthase 2
    Monoclonal Antibody for Human AdoMet synthase 2
    Monoclonal Antibody for Human AdoMet synthase 2
    Protein for Human AdoMet synthase 2
    Protein for Human AdoMet synthase 2
    Protein for Human AdoMet synthase 2

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    References
    1. 1.
      "Molecular cloning and developmental expression of a human kidney S-adenosylmethionine synthetase."
      Horikawa S. , Tsukada K.
      FEBS Lett.312:37-41(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Kidney.
    2. 2.
      "Activation of a novel isoform of methionine adenosyl transferase 2A and increased S-adenosylmethionine turnover in lung epithelial cells exposed to hyperoxia."
      Panayiotidis M.I. , Stabler S.P. , Ahmad A. , Pappa A. , Legros L.H. Jr. , Hernandez-Saavedra D. , Schneider B.K. , Allen R.H. , Vasiliou V. , McCord J.M. , Kotb M. , White C.W.
      Free Radic. Biol. Med.40:348-358(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Lung.
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Testis.
    4. 4.
      "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
      Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Muscle.
    7. 7.
      "Cloning, expression, and functional characterization of the beta regulatory subunit of human methionine adenosyltransferase (MAT II)."
      LeGros H.L. , Halim A.-B. , Geller A.M. , Kotb M.
      J. Biol. Chem.275:2359-2366(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-114;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    9. 9.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-81;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    10. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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