MET ELISA Kit for Human(Homo sapiens) | EIAab.comMET ELISA Kit for Human(Homo sapiens)

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Index > Protein center > MET(Gene name) > Human

MET (Gene name),

Hepatocyte growth factor receptor (Protein name ), MET_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Citations (1)

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Gene name:

MET;

Protein name:

Hepatocyte growth factor receptor(HGF receptor);

Alternative:

Proto-oncogene c-Met;HGF/SF receptor;Tyrosine-protein kinase Met;Scatter factor receptor(SF receptor);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Heterodimer formed of an alpha chain (50 kDa) and a beta chain (145 kDa) which are disulfide linked. Binds PLXNB1 and GRB2. Interacts with SPSB1, SPSB2 and SPSB4 (By similarity). Interacts with INPP5D/SHIP1. When phosphorylated at Tyr-1356, interacts with INPPL1/SHIP2. Interacts with RANBP9 and RANBP10, as well as SPSB1, SPSB2, SPSB3 and SPSB4. SPSB1 binding occurs in the presence and in the absence of HGF, however HGF treatment has a positive effect on this interaction. Interacts with MUC20; prevents interaction with GRB2 and suppresses hepatocyte growth factor-induced cell proliferation. Interacts with GRB10.

Function:

Receptor for hepatocyte growth factor and scatter factor. Has a tyrosine-protein kinase activity. Functions in cell proliferation, scattering, morphogenesis and survival.

Subcellular Location:

Membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

1390

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

900:

950:

1000:

1050:

1100:

1150:

1200:

1250:

1300:

1350:

1390:

HVNATYVNVK | CVAPYPSLLS | SEDNADDEVD | TRPASFWETS |

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

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Related Databases

Pfam:

PF07714

String:

P08581

MIM:

114550

SMR:

P08581

UniGene:

Hs.132966

KEGG:

hsa:4233

STRING:

9606.ENSP00000317272

Uniprot:

P08581

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ELISA Kit for Human HGF receptor

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ELISA Kit for Human HGF receptor

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E9559m

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96T

ELISA Kit for Human HGF receptor

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E9559r

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ELISA Kit for Human HGF receptor

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E9559h

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ELISA Kit for Human HGF receptor

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ELISA Kit for Human HGF receptor

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E9559p

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ELISA Kit for Human HGF receptor

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E9559b

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96T

CLIA Kit for Human HGF receptor

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U9559m

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96T

CLIA Kit for Human HGF receptor

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U9559b

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96T

CLIA Kit for Human HGF receptor

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U9559h

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CLIA Kit for Human HGF receptor

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U9559r

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96T

CLIA Kit for Human HGF receptor

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U9559p

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CLIA Kit for Human HGF receptor

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CLIA Kit for Human HGF receptor

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Polyclonal Antibody for Human HGF receptor

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P9559Rb-m

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Polyclonal Antibody for Human HGF receptor

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P9559Rb-h

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Polyclonal Antibody for Human HGF receptor

Monoclonal Antibody for Human HGF receptor

Protein for Human HGF receptor

R&D Technical Data

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Precision

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Citations

[1].

"Salivary levels and immunohistochemical expression of selected angiogenic factors in benign and malignant parotid gland tumours"

J Sokalski, D Trzybulska, M Bodnar, et al.

From:Clinical Oral Investigations

References

1.

"Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors."
Park M. , Dean M. , Kaul K. , Braun M.J. , Gonda M.A. , Vande Woude G.
Proc. Natl. Acad. Sci. U.S.A.84:6379-6383(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
2.

Giordano S.
Submitted (1990-11) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
3.

"Novel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritis."
Jin P. , Zhang J. , Sumariwalla P.F. , Ni I. , Jorgensen B. , Crawford D. , Phillips S. , Feldmann M. , Shepard H.M. , Paleolog E.M.
Arthritis Res. Ther.10:R73-R73(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3);ALTERNATIVE SPLICING
4.

"The DNA sequence of human chromosome 7."
Hillier L.W. , Fulton R.S. , Fulton L.A. , Graves T.A. , Pepin K.H. , Wagner-McPherson C. , Layman D. , Maas J. , Jaeger S. , Walker R. , Wylie K. , Sekhon M. , Becker M.C. , O'Laughlin M.D. , Schaller M.E. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , more...
Nature424:157-164(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"Human chromosome 7: DNA sequence and biology."
Scherer S.W. , Cheung J. , MacDonald J.R. , Osborne L.R. , Nakabayashi K. , Herbrick J.-A. , Carson A.R. , Parker-Katiraee L. , Skaug J. , Khaja R. , Zhang J. , Hudek A.K. , Li M. , Haddad M. , Duggan G.E. , Fernandez B.A. , Kanematsu E. , Gentles S. , more...
Science300:767-772(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

Mural R.J. , Istrail S. , Sutton G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Cerebellum.
8.

"Primary structure of the met protein tyrosine kinase domain."
Chan A.M.-L. , King H.W.S. , Tempest P.R. , Deakin E.A. , Cooper C.S. , Brookes P.
Oncogene1:229-233(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1010-1390
9.

"A survey of protein tyrosine kinase mRNAs expressed in normal human melanocytes."
Lee S.-T. , Strunk K.M. , Spritz R.A.
Oncogene8:3403-3410(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1206-1264
10.

"The human met oncogene is related to the tyrosine kinase oncogenes."
Dean M. , Park M. , le Beau M.M. , Robins T.S. , Diaz M.O. , Rowley J.D. , Blair D.G. , Vande Woude G.F.
Nature318:385-388(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1267-1390
11.

"The receptor encoded by the human c-MET oncogene is expressed in hepatocytes, epithelial cells and solid tumors."
Prat M. , Narsimhan R.P. , Crepaldi T. , Nicotra M.R. , Natali P.G. , Comoglio P.M.
Int. J. Cancer49:323-328(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
12.

"The tyrosine-phosphorylated hepatocyte growth factor/scatter factor receptor associates with phosphatidylinositol 3-kinase."
Graziani A. , Gramaglia D. , Cantley L.C. , Comoglio P.M.
J. Biol. Chem.266:22087-22090(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PIK3R1
13.

"Expression of the Met/HGF receptor in normal and neoplastic human tissues."
Di Renzo M.F. , Narsimhan R.P. , Olivero M. , Bretti S. , Giordano S. , Medico E. , Gaglia P. , Zara P. , Comoglio P.M.
Oncogene6:1997-2003(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
14.

"Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product."
Bottaro D.P. , Rubin J.S. , Faletto D.L. , Chan A.M.-L. , Kmiecik T.E. , Vande Woude G.F. , Aaronson S.A.
Science251:802-804(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
15.

"Identification of the major autophosphorylation site of the Met/hepatocyte growth factor receptor tyrosine kinase."
Ferracini R. , Longati P. , Naldini L. , Vigna E. , Comoglio P.M.
J. Biol. Chem.266:19558-19564(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT TYR-1235;ATP-BINDING SITE LYS-1110
16.

"A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family."
Ponzetto C. , Bardelli A. , Zhen Z. , Maina F. , dalla Zonca P. , Giordano S. , Graziani A. , Panayotou G. , Comoglio P.M.
Cell77:261-271(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT TYR-1349 AND TYR-1356;INTERACTION WITH SRC; PLCG1 AND GRB2
17.

"Hepatocyte growth factor/scatter factor effects on epithelia. Regulation of intercellular junctions in transformed and nontransformed cell lines, basolateral polarization of c-met receptor in transformed and natural intestinal epithelia, and induction of rapid wound repair in a transformed model epithelium."
Nusrat A. , Parkos C.A. , Bacarra A.E. , Godowski P.J. , Delp-Archer C. , Rosen E.M. , Madara J.L.
J. Clin. Invest.93:2056-2065(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN WOUND HEALING
18.

"Induction of epithelial tubules by growth factor HGF depends on the STAT pathway."
Boccaccio C. , Ando M. , Tamagnone L. , Bardelli A. , Michieli P. , Battistini C. , Comoglio P.M.
Nature391:285-288(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH STAT3
19.

"Grb10, a positive, stimulatory signaling adapter in platelet-derived growth factor BB-, insulin-like growth factor I-, and insulin-mediated mitogenesis."
Wang J. , Dai H. , Yousaf N. , Moussaif M. , Deng Y. , Boufelliga A. , Swamy O.R. , Leone M.E. , Riedel H.
Mol. Cell. Biol.19:6217-6228(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH GRB10
20.

"Activation of Ras/Erk pathway by a novel MET-interacting protein RanBPM."
Wang D. , Li Z. , Messing E.M. , Wu G.
J. Biol. Chem.277:36216-36222(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RANBP9
21.

"c-Cbl is involved in Met signaling in B cells and mediates hepatocyte growth factor-induced receptor ubiquitination."
Taher T.E. , Tjin E.P. , Beuling E.A. , Borst J. , Spaargaren M. , Pals S.T.
J. Immunol.169:3793-3800(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: UBIQUITINATION
22.

"The semaphorin 4D receptor controls invasive growth by coupling with Met."
Giordano S. , Corso S. , Conrotto P. , Artigiani S. , Gilestro G. , Barberis D. , Tamagnone L. , Comoglio P.M.
Nat. Cell Biol.4:720-724(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PLXNB1
23.

"Hepatocyte growth factor receptor tyrosine kinase met is a substrate of the receptor protein-tyrosine phosphatase DEP-1."
Palka H.L. , Park M. , Tonks N.K.
J. Biol. Chem.278:5728-5735(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT TYR-1230; TYR-1234; TYR-1235; TYR-1349 AND TYR-1365;DEPHOSPHORYLATION AT TYR-1349 AND TYR-1365 BY PTPRJ
24.

"A novel MET-interacting protein shares high sequence similarity with RanBPM, but fails to stimulate MET-induced Ras/Erk signaling."
Wang D. , Li Z. , Schoen S.R. , Messing E.M. , Wu G.
Biochem. Biophys. Res. Commun.313:320-326(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RANBP9 AND RANBP10
25.

"MUC20 suppresses the hepatocyte growth factor-induced Grb2-Ras pathway by binding to a multifunctional docking site of met."
Higuchi T. , Orita T. , Katsuya K. , Yamasaki Y. , Akiyama K. , Li H. , Yamamoto T. , Saito Y. , Nakamura M.
Mol. Cell. Biol.24:7456-7468(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH MUC20
26.

"The SH2-domain-containing inositol 5-phosphatase (SHIP)-2 binds to c-Met directly via tyrosine residue 1356 and involves hepatocyte growth factor (HGF)-induced lamellipodium formation, cell scattering and cell spreading."
Koch A. , Mancini A. , El Bounkari O. , Tamura T.
Oncogene24:3436-3447(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT TYR-1356;INTERACTION WITH INPPL1
27.

"Invasive growth: a MET-driven genetic programme for cancer and stem cells."
Boccaccio C. , Comoglio P.M.
Nat. Rev. Cancer6:637-645(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON FUNCTION IN ANGIOGENESIS
28.

"Regulation of the Met receptor-tyrosine kinase by the protein-tyrosine phosphatase 1B and T-cell phosphatase."
Sangwan V. , Paliouras G.N. , Abella J.V. , Dube N. , Monast A. , Tremblay M.L. , Park M.
J. Biol. Chem.283:34374-34383(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION;DEPHOSPHORYLATION BY PTPN1 AND PTPN2;INTERACTION WITH PTPN1 AND PTPN2;MUTAGENESIS OF TYR-1234 AND TYR-1235
29.

"Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
Daub H. , Olsen J.V. , Bairlein M. , Gnad F. , Oppermann F.S. , Korner R. , Greff Z. , Keri G. , Stemmann O. , Mann M.
Mol. Cell31:438-448(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-977 AND TYR-1003;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
30.

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-990; SER-997 AND SER-1000;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
31.

"Identification of N-glycosylation sites on secreted proteins of human hepatocellular carcinoma cells with a complementary proteomics approach."
Cao J. , Shen C. , Wang H. , Shen H. , Chen Y. , Nie A. , Yan G. , Lu H. , Liu Y. , Yang P.
J. Proteome Res.8:662-672(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-106
tissue: Hepatoma.
32.

"Large-scale proteomics analysis of the human kinome."
Oppermann F.S. , Gnad F. , Olsen J.V. , Hornberger R. , Greff Z. , Keri G. , Mann M. , Daub H.
Mol. Cell. Proteomics8:1751-1764(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-1003 AND THR-1289;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
33.

"The HGF/MET pathway as target for the treatment of multiple myeloma and B-cell lymphomas."
Mahtouk K. , Tjin E.P. , Spaargaren M. , Pals S.T.
Biochim. Biophys. Acta1806:208-219(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON FUNCTION
34.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
35.

"Distinct involvement of the Gab1 and Grb2 adaptor proteins in signal transduction by the related receptor tyrosine kinases RON and MET."
Chaudhuri A. , Xie M.H. , Yang B. , Mahapatra K. , Liu J. , Marsters S. , Bodepudi S. , Ashkenazi A.
J. Biol. Chem.286:32762-32774(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH GAB1
36.

"Dimer formation through domain swapping in the crystal structure of the Grb2-SH2-Ac-pYVNV complex."
Schiering N. , Casale E. , Caccia P. , Giordano P. , Battistini C.
Biochemistry39:13376-13382(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) OF 1356-1359 IN COMPLEX WITH GRB2
37.

"Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met and its complex with the microbial alkaloid K-252a."
Schiering N. , Knapp S. , Marconi M. , Flocco M.M. , Cui J. , Perego R. , Rusconi L. , Cristiani C.
Proc. Natl. Acad. Sci. U.S.A.100:12654-12659(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS) OF 1049-1360 IN COMPLEX WITH INHIBITOR
38.

"Insights into function of PSI domains from structure of the Met receptor PSI domain."
Kozlov G. , Perreault A. , Schrag J.D. , Park M. , Cygler M. , Gehring K. , Ekiel I.
Biochem. Biophys. Res. Commun.321:234-240(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 519-562;DISULFIDE BONDS
39.

"Crystal structure of the HGF beta-chain in complex with the Sema domain of the Met receptor."
Stamos J. , Lazarus R.A. , Yao X. , Kirchhofer D. , Wiesmann C.
EMBO J.23:2325-2335(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.22 ANGSTROMS) OF 25-567 IN COMPLEX WITH HGF;DISULFIDE BONDS
40.

"Structure of the human receptor tyrosine kinase met in complex with the Listeria invasion protein InlB."
Niemann H.H. , Jager V. , Butler P.J. , van den Heuvel J. , Schmidt S. , Ferraris D. , Gherardi E. , Heinz D.W.
Cell130:235-246(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF 25-740 IN COMPLEX WITH L.MONOCYTOGENES INLB;DISULFIDE BONDS
41.

"Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas."
Schmidt L. , Duh F.-M. , Chen F. , Kishida T. , Glenn G. , Choyke P. , Scherer S.W. , Zhuang Z. , Lubensky I. , Dean M. , Allikmets R. , Chidambaram A. , Bergerheim U.R. , Feltis J.T. , Casadevall C. , Zamarron A. , Bernues M. , Richard S. , more...
Nat. Genet.16:68-73(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS RCCP THR-1131; LEU-1188; VAL-1195; ILE-1220; HIS-1228; ASN-1228; CYS-1230; HIS-1230 AND THR-1250;VARIANT VAL-320
42.

"Two North American families with hereditary papillary renal carcinoma and identical novel mutations in the MET proto-oncogene."
Schmidt L. , Junker K. , Weirich G. , Glenn G. , Choyke P. , Lubensky I. , Zhuang Z. , Jeffers M. , Vande Woude G. , Neumann H. , Walther M. , Linehan W.M. , Zbar B.
Cancer Res.58:1719-1722(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT RCCP ARG-1094;CHARACTERIZATION OF VARIANT RCCP ARG-1094
43.

"Hereditary and sporadic papillary renal carcinomas with c-met mutations share a distinct morphological phenotype."
Lubensky I.A. , Schmidt L. , Zhuang Z. , Weirich G. , Pack S. , Zambrano N. , Walther M.M. , Choyke P. , Linehan W.M. , Zbar B.
Am. J. Pathol.155:517-526(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS RCCP ILE-1092; ARG-1094; ASP-1106; THR-1131; LEU-1188; ASP-1230; CYS-1230 AND THR-1250
44.

"Somatic mutations in the kinase domain of the Met/hepatocyte growth factor receptor gene in childhood hepatocellular carcinomas."
Park W.S. , Dong S.M. , Kim S.Y. , Na E.Y. , Shin M.S. , Pi J.H. , Kim B.J. , Bae J.H. , Hong Y.K. , Lee K.S. , Lee S.H. , Yoo N.J. , Jang J.J. , Pack S. , Zhuang Z. , Schmidt L. , Zbar B. , Lee J.Y.
Cancer Res.59:307-310(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS HCC ILE-1173; ARG-1244 AND ILE-1250
45.

"Novel mutation in the ATP-binding site of the MET oncogene tyrosine kinase in a HPRCC family."
Olivero M. , Valente G. , Bardelli A. , Longati P. , Ferrero N. , Cracco C. , Terrone C. , Rocca-Rossetti S. , Comoglio P.M. , Di Renzo M.F.
Int. J. Cancer82:640-643(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT RCCP ILE-1092;CHARACTERIZATION OF VARIANT RCCP ILE-1092
46.

"Novel mutations of the MET proto-oncogene in papillary renal carcinomas."
Schmidt L. , Junker K. , Nakaigawa N. , Kinjerski T. , Weirich G. , Miller M. , Lubensky I. , Neumann H.P.H. , Brauch H. , Decker J. , Vocke C. , Brown J.A. , Jenkins R. , Richard S. , Bergerheim U. , Gerrard B. , Dean M. , Linehan W.M. , more...
Oncogene18:2343-2350(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS RCCP ILE-1092; LEU-1094; TYR-1094; ASP-1106 AND ASP-1230;CHARACTERIZATION OF VARIANTS RCCP ILE-1092; LEU-1094; TYR-1094; ASP-1106 AND ASP-1230
47.

"A novel germ line juxtamembrane Met mutation in human gastric cancer."
Lee J.-H. , Han S.-U. , Cho H. , Jennings B. , Gerrard B. , Dean M. , Schmidt L. , Zbar B. , Vande Woude G.F.V.
Oncogene19:4947-4953(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT GASTRIC CANCER SER-991;VARIANT ILE-992;CHARACTERIZATION OF VARIANT GASTRIC CANCER SER-991;CHARACTERIZATION OF VARIANT ILE-992
48.

"A novel germline mutation in the MET extracellular domain in a Korean patient with the diffuse type of familial gastric cancer."
Kim I.-J. , Park J.-H. , Kang H.C. , Shin Y. , Lim S.-B. , Ku J.-L. , Yang H.-K. , Lee K.U. , Park J.-G.
J. Med. Genet.40:E97-E97(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT GASTRIC CANCER LEU-773
49.

"The SPRY domain-containing SOCS box protein 1 (SSB-1) interacts with MET and enhances the hepatocyte growth factor-induced Erk-Elk-1-serum response element pathway."
Wang D. , Li Z. , Messing E.M. , Wu G.
J. Biol. Chem.280:16393-16401(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SPSB1; SPSB2; SPSB3 AND SPSB4
50.

"A genetic variant that disrupts MET transcription is associated with autism."
Campbell D.B. , Sutcliffe J.S. , Ebert P.J. , Militerni R. , Bravaccio C. , Trillo S. , Elia M. , Schneider C. , Melmed R. , Sacco R. , Persico A.M. , Levitt P.
Proc. Natl. Acad. Sci. U.S.A.103:16834-16839(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: POSSIBLE INVOLVEMENT IN SUSCEPTIBILITY TO AUTS9;VARIANTS CYS-970 AND ILE-992
51.

"Patterns of somatic mutation in human cancer genomes."
Greenman C. , Stephens P. , Smith R. , Dalgliesh G.L. , Hunter C. , Bignell G. , Davies H. , Teague J. , Butler A. , Stevens C. , Edkins S. , O'Meara S. , Vastrik I. , Schmidt E.E. , Avis T. , Barthorpe S. , Bhamra G. , Buck G. , more...
Nature446:153-158(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS [LARGE SCALE ANALYSIS] GLN-143; LEU-156; ASP-168; SER-375; CYS-970 AND ILE-992
52.

"MET mutations in cancers of unknown primary origin (CUPs)."
Stella G.M. , Benvenuti S. , Gramaglia D. , Scarpa A. , Tomezzoli A. , Cassoni P. , Senetta R. , Venesio T. , Pozzi E. , Bardelli A. , Comoglio P.M.
Hum. Mutat.32:44-50(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS TYR-150; ASP-168; TYR-385; ILE-992 AND ILE-1294;CHARACTERIZATION OF VARIANTS TYR-150; ASP-168; TYR-385; ILE-992 AND ILE-1294;POSSIBLE INVOLVEMENT IN CUP

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