MAP1LC3A ELISA Kit for Human(Homo sapiens) | EIAab.comMAP1LC3A ELISA Kit for Human(Homo sapiens)

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Index > Protein center > MAP1LC3A(Gene name) > Human

MAP1LC3A (Gene name),

Microtubule-associated proteins 1A/1B light chain 3A (Protein name ), MLP3A_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

MAP1LC3A;

Protein name:

Microtubule-associated proteins 1A/1B light chain 3A;

Alternative:

Autophagy-related ubiquitin-like modifier LC3 A;Autophagy-related protein LC3 A;MAP1A/MAP1B light chain 3 A(MAP1A/MAP1B LC3 A);MAP1 light chain 3-like protein 1;Microtubule-associated protein 1 light chain 3 alpha;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins.

Function:

Probably involved in formation of autophagosomal vacuoles (autophagosomes).

Subcellular Location:

Cytoplasm cytoskeleton Endomembrane system Lipid-anchor Cytoplasmic vesicle autophagosome membrane Lipid-anchor LC3-II binds to the autophagic membranes.

Protein Attributes:

Sequence length:

121

Sequence:

50:

100:

121:

QEKDEDGFLY | MVYASQETFG | F

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q9H492

KEGG:

hsa:84557

UniGene:

Hs.632273

SMR:

Q9H492

MIM:

601242

Pfam:

PF02991

STRING:

9606.ENSP00000363970

Uniprot:

Q9H492

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ELISA Kit for Human Microtubule-associated proteins 1A/1B light chain 3A

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E2879h

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96T

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ELISA Kit for Human Microtubule-associated proteins 1A/1B light chain 3A

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E2879m

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ELISA Kit for Human Microtubule-associated proteins 1A/1B light chain 3A

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E2879r

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ELISA Kit for Human Microtubule-associated proteins 1A/1B light chain 3A

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E2879b

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96T

CLIA Kit for Human Microtubule-associated proteins 1A/1B light chain 3A

Cat.:

U2879b

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96T

CLIA Kit for Human Microtubule-associated proteins 1A/1B light chain 3A

Cat.:

U2879h

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MSDS:

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Packing:

96T

CLIA Kit for Human Microtubule-associated proteins 1A/1B light chain 3A

Cat.:

U2879r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Microtubule-associated proteins 1A/1B light chain 3A

Cat.:

U2879m

Price:

Please sign in first.

MSDS:

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Packing:

96T

Polyclonal Antibody for Human Microtubule-associated proteins 1A/1B light chain 3A

Cat.:

P2879Rb-h

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40ug/0.2ml

Polyclonal Antibody for Human Microtubule-associated proteins 1A/1B light chain 3A

Cat.:

P2879Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Microtubule-associated proteins 1A/1B light chain 3A

Cat.:

P2879Rb-r

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Microtubule-associated proteins 1A/1B light chain 3A

Protein for Human Microtubule-associated proteins 1A/1B light chain 3A

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"Post-translational modifications of three members of the human MAP1LC3 family and detection of a novel type of modification for MAP1LC3B."
He H. , Dang Y. , Dai F. , Guo Z. , Wu J. , She X. , Pei Y. , Chen Y. , Ling W. , Wu C. , Zhao S. , Liu J.O. , Yu L.
J. Biol. Chem.278:29278-29287(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);SUBCELLULAR LOCATION;TISSUE SPECIFICITY;MUTAGENESIS OF GLY-120
2.

"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
Submitted (2003-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
3.

"The full-ORF clone resource of the German cDNA consortium."
Bechtel S. , Rosenfelder H. , Duda A. , Schmidt C.P. , Ernst U. , Wellenreuther R. , Mehrle A. , Schuster C. , Bahr A. , Bloecker H. , Heubner D. , Hoerlein A. , Michel G. , Wedler H. , Koehrer K. , Ottenwaelder B. , Poustka A. , Wiemann S. , more...
BMC Genomics8:399-399(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Amygdala.
4.

"The DNA sequence and comparative analysis of human chromosome 20."
Deloukas P. , Matthews L.H. , Ashurst J.L. , Burton J. , Gilbert J.G.R. , Jones M. , Stavrides G. , Almeida J.P. , Babbage A.K. , Bagguley C.L. , Bailey J. , Barlow K.F. , Bates K.N. , Beard L.M. , Beare D.M. , Beasley O.P. , Bird C.P. , Blakey S.E. , more...
Nature414:865-871(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] (ISOFORMS 1 AND 2)
5.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Uterus.
7.

"The human homolog of Saccharomyces cerevisiae Apg7p is a Protein-activating enzyme for multiple substrates including human Apg12p, GATE-16, GABARAP, and MAP-LC3."
Tanida I. , Tanida-Miyake E. , Ueno T. , Kominami E.
J. Biol. Chem.276:1701-1706(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ATG7
8.

"Human Apg3p/Aut1p homologue is an authentic E2 enzyme for multiple substrates, GATE-16, GABARAP, and MAP-LC3, and facilitates the conjugation of hApg12p to hApg5p."
Tanida I. , Tanida-Miyake E. , Komatsu M. , Ueno T. , Kominami E.
J. Biol. Chem.277:13739-13744(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ATG3
9.

"HsAtg4B/HsApg4B/autophagin-1 cleaves the carboxyl termini of three human Atg8 homologues and delipidates microtubule-associated protein light chain 3- and GABAA receptor-associated protein-phospholipid conjugates."
Tanida I. , Sou Y.-S. , Ezaki J. , Minematsu-Ikeguchi N. , Ueno T. , Kominami E.
J. Biol. Chem.279:36268-36276(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: LIPIDATION AT GLY-120;CLEAVAGE BY APG4B
10.

"p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy."
Pankiv S. , Clausen T.H. , Lamark T. , Brech A. , Bruun J.A. , Outzen H. , Overvatn A. , Bjorkoy G. , Johansen T.
J. Biol. Chem.282:24131-24145(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SQSTM1;SUBCELLULAR LOCATION
11.

"The TP53INP2 protein is required for autophagy in mammalian cells."
Nowak J. , Archange C. , Tardivel-Lacombe J. , Pontarotti P. , Pebusque M.J. , Vaccaro M.I. , Velasco G. , Dagorn J.C. , Iovanna J.L.
Mol. Biol. Cell20:870-881(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;INTERACTION WITH TP53INP2
12.

"Regulation of the autophagy protein LC3 by phosphorylation."
Cherra S.J. III , Kulich S.M. , Uechi G. , Balasubramani M. , Mountzouris J. , Day B.W. , Chu C.T.
J. Cell Biol.190:533-539(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-12 BY PKA;FUNCTION
13.

"TP53INP1, a tumor suppressor, interacts with LC3 and ATG8-family proteins through the LC3-interacting region (LIR) and promotes autophagy-dependent cell death."
Seillier M. , Peuget S. , Gayet O. , Gauthier C. , N'guessan P. , Monte M. , Carrier A. , Iovanna J.L. , Dusetti N.J.
Cell Death Differ.19:1525-1535(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
14.

"ATG8 family proteins act as scaffolds for assembly of the ULK complex: sequence requirements for LC3-interacting region (LIR) motifs."
Alemu E.A. , Lamark T. , Torgersen K.M. , Birgisdottir A.B. , Larsen K.B. , Jain A. , Olsvik H. , Overvatn A. , Kirkin V. , Johansen T.
J. Biol. Chem.287:39275-39290(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ATG13 AND ULK1
15.

"Rab GTPase-activating proteins in autophagy: regulation of endocytic and autophagy pathways by direct binding to human ATG8 modifiers."
Popovic D. , Akutsu M. , Novak I. , Harper J.W. , Behrends C. , Dikic I.
Mol. Cell. Biol.32:1733-1744(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TBC1D5
16.

"DOR/Tp53inp2 and Tp53inp1 constitute a metazoan gene family encoding dual regulators of autophagy and transcription."
Sancho A. , Duran J. , Garcia-Espana A. , Mauvezin C. , Alemu E.A. , Lamark T. , Macias M.J. , Desalle R. , Royo M. , Sala D. , Chicote J.U. , Palacin M. , Johansen T. , Zorzano A.
PLoS ONE7:E34034-E34034(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TP53INP1 AND TP53INP2
17.

"The Legionella effector RavZ inhibits host autophagy through irreversible Atg8 deconjugation."
Choy A. , Dancourt J. , Mugo B. , O'Connor T.J. , Isberg R.R. , Melia T.J. , Roy C.R.
Science338:1072-1076(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DECONJUGATION BY LEGIONELLA RAVZ

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