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Index > Protein center > MMP24(Gene name) > Human
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  • MMP24 (Gene name),
  • Matrix metalloproteinase-24 (Protein name ),  MMP24_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    MMP24(MT5MMP);
    Protein name:
    Matrix metalloproteinase-24(MMP-24);
    Alternative:
    Membrane-type-5 matrix metalloproteinase(MT5-MMP;MT5MMP);Membrane-type matrix metalloproteinase 5(MT-MMP 5;MTMMP5);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Activates progelatinase A. May also be a proteoglycanase involved in degradation of proteoglycans, such as dermatan sulfate and chondroitin sulfate proteoglycans. Cleaves partially fibronectin, but not collagen type I, nor laminin.
    Subcellular Location:
    Processed matrix metalloproteinase-24 Secreted extracellular space extracellular matrix Also shed from cell surface as soluble proteinase, by a proteolytic cleavage.
    Protein Attributes:
    Sequence length:
    645
    Sequence:
    50:
    MPRSRGGRAA | PGPPPPPPPP | GQAPRWSRWR | VPGRLLLLLL | PALCCLPGAA | 
    100:
    RAAAAAAGAG | NRAAVAVAVA | RADEAEAPFA | GQNWLKSYGY | LLPYDSRASA | 
    150:
    LHSAKALQSA | VSTMQQFYGI | PVTGVLDQTT | IEWMKKPRCG | VPDHPHLSRR | 
    200:
    RRNKRYALTG | QKWRQKHITY | SIHNYTPKVG | ELDTRKAIRQ | AFDVWQKVTP | 
    250:
    LTFEEVPYHE | IKSDRKEADI | MIFFASGFHG | DSSPFDGEGG | FLAHAYFPGP | 
    300:
    GIGGDTHFDS | DEPWTLGNAN | HDGNDLFLVA | VHELGHALGL | EHSSDPSAIM | 
    350:
    APFYQYMETH | NFKLPQDDLQ | GIQKIYGPPA | EPLEPTRPLP | TLPVRRIHSP | 
    400:
    SERKHERQPR | PPRPPLGDRP | STPGTKPNIC | DGNFNTVALF | RGEMFVFKDR | 
    450:
    WFWRLRNNRV | QEGYPMQIEQ | FWKGLPARID | AAYERADGRF | VFFKGDKYWV | 
    500:
    FKEVTVEPGY | PHSLGELGSC | LPREGIDTAL | RWEPVGKTYF | FKGERYWRYS | 
    550:
    EERRATDPGY | PKPITVWKGI | PQAPQGAFIS | KEGYYTYFYK | GRDYWKFDNQ | 
    600:
    KLSVEPGYPR | NILRDWMGCN | QKEVERRKER | RLPQDDVDIM | VTINDVPGSV | 
    645:
    NAVAVVIPCI | LSLCILVLVY | TIFQFKNKTG | PQPVTYYKRP | VQEWV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    MIM:
    Pfam:
    SMR:
    KEGG:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human MMP-24
    Cat.:
    E0555m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human MMP-24
    Cat.:
    E0555r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human MMP-24
    Cat.:
    E0555h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human MMP-24
    Cat.:
    U0555m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human MMP-24
    Cat.:
    U0555h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human MMP-24
    Cat.:
    U0555r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human MMP-24
    Cat.:
    P0555Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human MMP-24
    Cat.:
    P0555Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human MMP-24
    Cat.:
    P0555Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human MMP-24
    Monoclonal Antibody for Human MMP-24
    Monoclonal Antibody for Human MMP-24
    Protein for Human MMP-24
    Protein for Human MMP-24
    Protein for Human MMP-24

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    References
    1. 1.
      "Identification and characterization of human MT5-MMP, a new membrane-bound activator of progelatinase a overexpressed in brain tumors."
      Llano E. , Pendas A.M. , Freije J.P. , Nakano A. , Knaeuper V. , Murphy G. , Lopez-Otin C.
      Cancer Res.59:2570-2576(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
      tissue: Brain.
    2. 2.
      "Identification of a new membrane-type matrix metalloproteinase, MT5-MMP, that is expressed predominantly in cerebellum."
      Seiki M.
      Submitted (1998-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "The DNA sequence and comparative analysis of human chromosome 20."
      Deloukas P. , Matthews L.H. , Ashurst J.L. , Burton J. , Gilbert J.G.R. , Jones M. , Stavrides G. , Almeida J.P. , Babbage A.K. , Bagguley C.L. , Bailey J. , Barlow K.F. , Bates K.N. , Beard L.M. , Beare D.M. , Beasley O.P. , Bird C.P. , Blakey S.E. , more...
      Nature414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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