Mmp2 ELISA Kit for Mouse(Mus musculus) | EIAab.comMmp2 ELISA Kit for Mouse(Mus musculus)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > Mmp2(Gene name) > Mouse

Mmp2 (Gene name),

72 kDa type IV collagenase (Protein name ), MMP2_MOUSE from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

Mmp2;

Protein name:

72 kDa type IV collagenase;

Alternative:

Gelatinase A;72 kDa gelatinase;Matrix metalloproteinase-2(MMP-2);

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts (via the C-terminal hemopexin-like domains-containing region) with the integrin alpha-V/beta-3; the interaction promotes vascular invasion in angiogenic vessels and melamoma cells. Interacts (via the C-terminal PEX domain) with TIMP2 (via the C-terminal); the interaction inhibits the degradation activity. Interacts with GSK3B.

Function:

PEX, the C-terminal non-catalytic fragment of MMP2, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin. Ligand for integrin alpha-v/beta-3 on the surface of blood vessels.

Subcellular Location:

Secreted extracellular space extracellular matrix Membrane Nucleus Colocalizes with integrin alphaV/beta3 at the membrane surface in angiogenic blood vessels and melanomas. Found in mitochondria, along microfibrils, and in nuclei of cardiomyocytes.

Protein Attributes:

Sequence length:

662

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

662:

KFGSIKSDWL | GC

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

KEGG:

mmu:17390

SMR:

P33434

UniGene:

Mm.29564

Pfam:

PF00040

String:

P33434

Uniprot:

P33434

FOR

ELISA Kit for Mouse 72 kDa type IV collagenase

Cat.:

E0100m

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Mouse 72 kDa type IV collagenase

Cat.:

E0100h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Mouse 72 kDa type IV collagenase

Cat.:

E0100r

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Mouse 72 kDa type IV collagenase

MSDS:

Please sign in first.

ELISA Kit for Mouse 72 kDa type IV collagenase

Cat.:

E0100c

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Mouse 72 kDa type IV collagenase

Cat.:

E0100b

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Mouse 72 kDa type IV collagenase

MSDS:

Please sign in first.

CLIA Kit for Mouse 72 kDa type IV collagenase

Cat.:

U0100r

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Mouse 72 kDa type IV collagenase

Cat.:

U0100h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Mouse 72 kDa type IV collagenase

Cat.:

U0100m

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Mouse 72 kDa type IV collagenase

Cat.:

U0100b

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Mouse 72 kDa type IV collagenase

Cat.:

U0100c

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Mouse 72 kDa type IV collagenase

Cat.:

P0100Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse 72 kDa type IV collagenase

Cat.:

P0100Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse 72 kDa type IV collagenase

Cat.:

P0100Rb-r

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse 72 kDa type IV collagenase

Protein for Mouse 72 kDa type IV collagenase

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Molecular cloning of murine 72-kDa type IV collagenase and its expression during mouse development."
Reponen P. , Sahlberg C. , Huhtala P. , Hurskainen T. , Thesleff I. , Tryggvason K.
J. Biol. Chem.267:7856-7862(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
strain: C57BL/6.
tissue: Brain.
3.

"Genes for extracellular-matrix-degrading metalloproteinases and their inhibitor, TIMP, are expressed during early mammalian development."
Brenner C.A. , Adler R.R. , Rappolee D.A. , Pedersen R.A. , Werb Z.
Genes Dev.3:848-859(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DEVELOPMENTAL STAGE
tissue: Embryo.
4.

"A novel intracellular isoform of matrix metalloproteinase-2 induced by oxidative stress activates innate immunity."
Lovett D.H. , Mahimkar R. , Raffai R.L. , Cape L. , Maklashina E. , Cecchini G. , Karliner J.S.
PLoS ONE7:E34177-E34177(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ALTERNATIVE SPLICING (ISOFORM 2);FUNCTION;SUBCELLULAR LOCATION

Product Feedback Wall

* Email:
*Comments: