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Index > Protein center > MOCOS(Gene name) > Human
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  • MOCOS (Gene name),
  • Molybdenum cofactor sulfurase (Protein name ),  MOCOS_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    MOCOS;
    Protein name:
    Molybdenum cofactor sulfurase(MCS;MOS;MoCo sulfurase;hMCS);
    Alternative:
    Molybdenum cofactor sulfurtransferase;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    888
    Sequence:
    50:
    MAGAAAESGR | ELWTFAGSRD | PSAPRLAYGY | GPGSLRELRA | REFSRLAGTV | 
    100:
    YLDHAGATLF | SQSQLESFTS | DLMENTYGNP | HSQNISSKLT | HDTVEQVRYR | 
    150:
    ILAHFHTTAE | DYTVIFTAGS | TAALKLVAEA | FPWVSQGPES | SGSRFCYLTD | 
    200:
    SHTSVVGMRN | VTMAINVIST | PVRPEDLWSA | EERSASASNP | DCQLPHLFCY | 
    250:
    PAQSNFSGVR | YPLSWIEEVK | SGRLHPVSTP | GKWFVLLDAA | SYVSTSPLDL | 
    300:
    SAHQADFVPI | SFYKIFGFPT | GLGALLVHNR | AAPLLRKTYF | GGGTASAYLA | 
    350:
    GEDFYIPRQS | VAQRFEDGTI | SFLDVIALKH | GFDTLERLTG | GMENIKQHTF | 
    400:
    TLAQYTYVAL | SSLQYPNGAP | VVRIYSDSEF | SSPEVQGPII | NFNVLDDKGN | 
    450:
    IIGYSQVDKM | ASLYNIHLRT | GCFCNTGACQ | RHLGISNEMV | RKHFQAGHVC | 
    500:
    GDNMDLIDGQ | PTGSVRISFG | YMSTLDDVQA | FLRFIIDTRL | HSSGDWPVPQ | 
    550:
    AHADTGETGA | PSADSQADVI | PAVMGRRSLS | PQEDALTGSR | VWNNSSTVNA | 
    600:
    VPVAPPVCDV | ARTQPTPSEK | AAGVLEGALG | PHVVTNLYLY | PIKSCAAFEV | 
    650:
    TRWPVGNQGL | LYDRSWMVVN | HNGVCLSQKQ | EPRLCLIQPF | IDLRQRIMVI | 
    700:
    KAKGMEPIEV | PLEENSERTQ | IRQSRVCADR | VSTYDCGEKI | SSWLSTFFGR | 
    750:
    PCHLIKQSSN | SQRNAKKKHG | KDQLPGTMAT | LSLVNEAQYL | LINTSSILEL | 
    800:
    HRQLNTSDEN | GKEELFSLKD | LSLRFRANII | INGKRAFEEE | KWDEISIGSL | 
    850:
    RFQVLGPCHR | CQMICIDQQT | GQRNQHVFQK | LSESRETKVN | FGMYLMHASL | 
    888:
    DLSSPCFLSV | GSQVLPVLKE | NVEGHDLPAS | EKHQDVTS
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    KEGG:
    MIM:
    UniGene:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human MCS
    Cat.:
    E13459h
    Price:
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human MCS
    MSDS:
    Please sign in first.
    ELISA Kit for Human MCS
    Cat.:
    E13459m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human MCS
    Cat.:
    U13459m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human MCS
    MSDS:
    Please sign in first.
    CLIA Kit for Human MCS
    Cat.:
    U13459h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human MCS
    Polyclonal Antibody for Human MCS
    Polyclonal Antibody for Human MCS
    Monoclonal Antibody for Human MCS
    Monoclonal Antibody for Human MCS
    Monoclonal Antibody for Human MCS
    Protein for Human MCS
    Protein for Human MCS
    Protein for Human MCS

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Mutation of human molybdenum cofactor sulfurase gene is responsible to classical xanthinuria type II."
      Ichida K. , Matsumura T. , Sakuma R. , Hosoya T. , Nishino T.
      Biochem. Biophys. Res. Commun.282:1194-1200(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];INVOLVEMENT IN XU2;VARIANTS ARG-225 AND ASN-703
    2. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANTS ILE-170; GLY-184; ARG-225; MET-358 AND ASN-703
      tissue: Liver.
    3. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANTS ILE-170; GLY-184; ARG-225 AND MET-358
      tissue: Lung.
    4. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 95-888;VARIANTS ILE-170 GLY-184; ARG-225 AND MET-358
      tissue: Melanoma.
    5. 6.
      "Identification of the missing component in the mitochondrial benzamidoxime prodrug converting system as a novel molybdenum enzyme."
      Havemeyer A. , Bittner F. , Wollers S. , Mendel R. , Kunze T. , Clement B.
      J. Biol. Chem.281:34796-34802(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;COFACTOR;BIOPHYSICOCHEMICAL PROPERTIES
    6. 7.
      "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."
      Beausoleil S.A. , Villen J. , Gerber S.A. , Rush J. , Gygi S.P.
      Nat. Biotechnol.24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-528 AND SER-530;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    7. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-528 AND SER-530;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    8. 9.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    9. 10.
      "Classical xanthinuria type 2 associated with a missense mutation in HMCS, the gene encoding molybdenum cofactor sulfurase."
      Finckh U. , Haddad M. , Lukacs Z. , Wagener C. , Gal A.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT XU2 ILE-294
    10. 11.
      "Identification of a new point mutation in the human molybdenum cofactor sulferase gene that is responsible for xanthinuria type II."
      Yamamoto T. , Moriwaki Y. , Takahashi S. , Tsutsumi Z. , Tuneyoshi K. , Matsui K. , Cheng J. , Hada T.
      Metabolism52:1501-1504(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT XU2 PRO-57
    11. 12.
      "Identification and characterization of the first mutation (Arg776Cys) in the C-terminal domain of the human molybdenum cofactor sulfurase (HMCS) associated with type II classical xanthinuria."
      Peretz H. , Naamati M.S. , Levartovsky D. , Lagziel A. , Shani E. , Horn I. , Shalev H. , Landau D.
      Mol. Genet. Metab.91:23-29(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT XU2 CYS-776
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